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All Journal Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter Jurnal Ilmiah Ilmu Terapan Universitas Jambi
Abdullah Azmy
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Anti-bacterial activity of rosella flowers extract (Hibiscus sabdariffa linn) in inhibiting bacterial growth methicillin-resistant Staphylococcus aureus Zinatul Hayati; Winda Yulia; T. Fadrial Karmil; Abdullah Azmy
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 2, No 1 (2012): Life Sciences
Publisher : Syiah Kuala University

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Abstract

Infections caused by bacteria Methycillin Resistant Staphylococcus aureus (MRSA) has become a worldwide health problem because of its increasing incidence. Rosella flower (Hibiscus sabdariffa Linn) has been known to have efficacy as an antibacterial. The purpose of this study is to determine the antibacterial activity of rosella flower extract in inhibiting the growth of MRSA. This study is an experimental research laboratory using rosella flower extract as a treatment, vancomycin as a positive control and distilled water as negative control. Fresh and dried rosella flowers crushed and then macerated with 96% ethanol for 24 hours. The filtrate obtained was concentrated by rotary evaporator at a temperature of 35 ˚ C-40 ˚ C and then diluted to a concentration of 12.5%, 25%, 50% and 75%. Phytochemical test is then performed. S.aureus bacteria isolated from clinical specimens in RSUDZA. Test of the antibacterial activity of rosella flower extract performed using Kirby Bauer disc diffusion method. Parameters on the disc were measured in millimeters MRSA. The data obtained were statistically analyzed and grouped into categories of Greenwood (1995). Phytochemical test results indicate the presence of rosella flower extract contains flavonoids, tannins, saponins, triterpenoids and alkaloids. Test results of the inhibition of rosella flower extract concentration of 12.5%, 25%, 50% and 75% of the growth of MRSA each inhibitory zone formed with an average diameter of 14.2 mm, 19.2 mm, 22.8 mm and 24.18 mm, whereas the positive control and negative control respectively of 19.8 mm and 5 mm. The results of data analysis showed that the ethanol extract of rosella flowers significant effect in inhibiting the growth of MRSA by the value of p 0.05. Based on the criteria of Greenwood, rosella flower extract ethanol concentration of 50% and 75% belong to the category of strong inhibitory power in inhibiting the growth of MRSA, a concentration of 25% falls into the category of being and the concentration of 12.5% falls into the category of weak. The results can be concluded that rosella flower ethanol extract can inhibit the growth of MRSA.
THE RELATIONSHIP BETWEEN SPINOPELVIC PARAMETERS ON RADIOGRAPHY AND THE DEGREE OF LUMBOSACRAL INTERVERTEBRAL DISC HERNIATION ON MRI Nasrizarni, Nasrizarni; Darinafitri, Irma; Azmy, Abdullah
Jurnal Ilmiah Ilmu Terapan Universitas Jambi Vol. 9 No. 4 (2025): Volume 9, Nomor 4, December 2025
Publisher : LPPM Universitas Jambi

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Background: The orientation and morphology of the sacropelvic can lead to structural changes and disc herniation, resulting in low back pain. Objective: To analyze the relationship between spinopelvic parameters and the degree of lumbosacral intervertebral disc herniation. Methods: This research is a retrospective analytic observational study with a cross-sectional design. The study included 52 patients with low back pain who underwent lumbosacral radiography and MRI at Saiful Anwar General Hospital in 2022–2023. The degree of disc herniation was assessed on sagittal and axial lumbosacral MRI, and pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT), lumbar lordosis (LL), lumbosacral angle (LSA), sacral table angle (STA), and sacral kyphosis (SK) were measured on lumbosacral radiographs. Statistical tests were conducted on four groups (normal, bulging, protrusion, and extrusion). Results: Lumbosacral disc herniation occurred most frequently in patients aged 51–60 years (30.76%), was more common in females (53.8%), and was most prevalent at levels L4–L5 and L5–S1. Using Spearman’s test, a correlation was found between lumbar lordosis angle and the degree of lumbosacral intervertebral disc herniation, with p=0.011 (p<0.05). One-way ANOVA showed a significant difference in lumbar lordosis across herniation grades, with p=0.028 (p<0.05). A smaller lumbar lordosis angle was associated with a higher risk of lumbosacral intervertebral disc herniation. Conclusion: Lumbar lordosis, as one of the spinopelvic parameters, may be considered a predictive factor for degenerative lumbosacral disc herniation.
Co-Authors Darinafitri, Irma Nasrizarni, Nasrizarni T. Fadrial Karmil Winda Yulia Zinatul Hayati