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ANALISIS POTENSI TERJADINYA MEDICATION ERROR PADA RESEP PASIEN RAWAT JALAN DI RUMAH SAKIT “X” KABUPATEN MALANG Hardani, Ika; Setiadi, Antonius Adji Prayitno; Wibowo, Yosi Irawati; Susanti, Erna
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 13 No 1 (2024): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v13i1.315

Abstract

Medication error adalah setiap kejadian yang menyebabkan pelayanan obat tidak tepat atau membahayakan pasien yang dapat dihindari. Tujuan penelitian untuk mengetahui prevalensi terjadinya medication error pada tahap prescribing dan transcribing pasien Rawat Jalan poli Interna, Saraf dan Anak. Penelitian dilakukan secara cross-sectional, pengambilan data dilakukan secara retrospektif dari data sekunder dengan melihat resep yang masuk ke Instalasi Farmasi Rawat Jalan Rumah Sakit “X” Kabupaten Malang sejumlah 375 sampel resep pada periode bulan Juni – Agustus 2023. Dari penelitian ini didapatkan analisis kelengkapan resep yang berpotensi menjadi penyebab medication error pada tahap prescribing penulisan resep tidak jelas sebesar 7,47%, diikuti kelengkapan identitas pasien yang tidak tepat sebesar 3,74%. Sedangkan tahap transcribing adanya duplikasi obat pada penulisan resep sebesar 5,07%, diikuti adanya interaksi obat dalam penulisan resep sebesar 29,33%. Kategori Interaksi obat berdasarkan hasil keparahan interaksi obat dari 375 resep terdapat 110 resep yang memiliki interaksi obat dengan persentase sebesar 29,33%. Dari 110 resep yang teridentifikasi interaksi obat, didapatkan interaksi mayor pada 10 resep dengan persentase 9,09%, interaksi moderate pada 96 resep dengan persentase 87,27% dan interaksi minor pada 4 resep dengan persentase 3,64%. Berdasarkan data disimpulkan bahwa masih terjadi medication error pada tahap prescribing dan transcribing di Rumah Sakit “X” Kabupaten Malang
Penggunaan DAPT (Dual Antiplatelet) Pada CVA (Cerebrovascular Accident) Trombosis atau Stroke Iskemik dengan Riwayat PJK (Penyakit Jantung Koroner) Putri, Rizky Ayu Artama; Badriah, Rani Nur; Anggraeni, Reta; Pratama, Jainuri Erik; Setiadi, Antonius Adji Prayitno; Herawati, Fauna; Gondokesumo, Marisca Evalina
MAHESA : Malahayati Health Student Journal Vol 4, No 12 (2024): Volume 4 Nomor 12 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i12.16289

Abstract

ABSTRACT Ischemic stroke is the sudden development of focal neurological deficit due to inadequate blood supply to an area of the brain, which can be thrombotic or embolic. CAD (Coronary Artery Disease) is pathological process characterized by the formation of atherosclerotic plaque followed by rupture, ulceration, or erosion. CAD can take the form of CCS (Chronic Coronary Syndrome). The 2018 AHA/ASA Guidline Antiplatelet Therapy used for ischemic stroke is Aspirin at a dose of 160mg-300mg 1x1. In the 2019 ESC Guidline, CCS patient therapy uses DAPT (Dual antiplatelet). In a 2021 AHA meta-analysis compared with aspirin alone, short-term DAPT within 24 hours after mild-moderate ischemic stroke reduced the risk of recurrent stroke at the expense of a higher risk of major bleeding. Here we present a case of a 76 year old female patient with ischemic stroke and CCS who used DAPT. Complaints of sluggishness, weakness in the left half of the body, acute dysarthria onset on the first day, when waking up. Hemiplegia S 1 week ago onset of waking up and being treated at Mataram Regional Hospital. The patient received the antiplatelet Aspirin 160mg 1x1 a day then switched DAPT (Aspirin 80mg 1x1 and Clopidogrel 75mg 1x1) due to a history of CCS. Keywords: CVA Thrombosis, Ischemic stroke, Aspilet, Clopidogrel, Coronary Artery Disease  ABSTRAK Stroke iskemik adalah perkembangan fokal yang tiba-tiba terjadi defisit neurologis akibat suplai oksigen tidak memadai ke suatu area pada otak, dapat bersifat trombotik atau emboli. PJK (Penyakit Jantung Koroner) atau CAD (Coronary Artery Disease) adalah proses patologis ditandai dengan terbentuknya plak aterosklerotik diikuti dengan pecah, ulserasi, atau erosi. PJK dapat berupa penyakit CCS (Chronic Coronary Syndrome). Terapi Antiplatelet Guidline AHA/ASA 2018 yang digunakan pada stroke iskemik adalah Aspirin dosis 160mg-300mg 1x1. Pada Guidline ESC 2019 terapi pasien CCS digunakan DAPT (Dual antiplatelet). Pada meta analisis AHA 2021 dibandingkan dengan aspirin saja, DAPT jangka pendek dalam waktu 24 jam setelah stroke iskemik ringan-sedang mengurangi risiko stroke berulang dengan mengorbankan risiko perdarahan besar yang lebih tinggi. Berikut kami presentasikan sebuah kasus pasien Perempuan 76 tahun dengan Stroke Iskemik dan CCS yang menggunakan DAPT. Keluhann pelo, kelemahan separuh badan kiri, acute disartria onset hari pertama, saat bangun tidur. Hemiplegia S 1 minggu lalu onset bangun tidur di rawat di RSUD Mataram. Pasien menerima antiplatelet Aspirin 160mg 1x1 sehari lalu switch DAPT (Aspirin 80mg 1x1 dan Clopidogrel 75mg 1x1) karena Riwayat CCS.  Kata Kunci: CVA trombosis, Ischemic stroke, Aspilet, Clopidogrel, Penyakit Jantung Koroner.
PATTERNS OF DRUG ABUSE AND PREVALENCE OF DEPENDENCE IN SURABAYA CITY Gresika, Ade Marda; Setiadi, Antonius Adji Prayitno
HEARTY Vol 13 No 3 (2025): JUNI
Publisher : Fakultas Ilmu Kesehatan, Universitas Ibn Khaldun, Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/hearty.v13i3.20046

Abstract

The negative effects of improper use of drugs have also been increasingly reported. Physical effects experienced by drug users include heart problems, disturbances in the brain's work, disorders of the nervous system, infection with dangerous infectious diseases such as HIV / AIDS and others. Meanwhile, the psychological or mental effects that will be experienced by abusers are attitude and mental changes. The purpose of this study was to obtain a percentage of grouping individual characteristics, patterns of abuse and prevalence of drug dependence. The type of research used is descriptive method with quantitative data collection and presentation. The research design used was an ex-post facto research design. In the ex-post facto study there were no control groups or pre-test activities. The sampling technique that will be used in this study is purposive sampling technique. Data collection methods used are questionnaire and interview methods. This study was dominated by men (83.78%), the highest age range was at the age of 16 25 years (37.84%), the latest education was dominated by high school graduates / equivalent (54.05%), dominated by entrepreneurs (51.35%), with part time work time (43.24%), living together with the nuclear family (86.49%). Environmental factors are the most factors which cause respondents to use drugs (86.50%). The methadone maintenance program is only known to heroin users.
Kajian Literatur : Harapan Pasien Terhadap Layanan Konseling di Apotek Auliyana, Iftitah Putri; Setiadi, Antonius Adji Prayitno; Wibowo, Yosi Irawati; Gondokesumo, Marisca Evalina
MAHESA : Malahayati Health Student Journal Vol 5, No 6 (2025): Volume 5 Nomor 6 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i6.18098

Abstract

ABSTRACT Drug Counseling is an interactive process between pharmacists and patients/families to increase knowledge, understanding, awareness and compliance so that changes in behavior in drug use occur and resolve problems faced by the patients. This literature review aims to look at the expectations that affect patient or consumer involvement in counseling at the pharmacy. The articles in this literature review use one database, namely Pubmed. Search results using the keyword combination (community pharmacy) AND (counseling OR communication OR patient counseling factors OR patient participation) AND (patient expectations) yielded 408 articles that met the inclusion criteria in this study are 13 articles. The results of the literature review show that the expectations that affects the patient or consumer involvement in counseling at the pharmacy are providing good information with appropriate communication skills, the layout of the pharmacy and the relationship between the pharmacist or pharmacist staff and the patient being good, friendly and polite. Keywords: Community Pharmacy, Counseling, Patient Counseling, Patient Expectations, Patient Participation. ABSTRACT Konseling Obat merupakan proses interaktif antara apoteker dengan pasien/keluarga untuk meningkatkan pengetahuan, pemahaman, kesadaran dan kepatuhan sehingga terjadi perubahan perilaku dalam penggunaan obat dan menyelesaikan masalah yang dihadapi pasien. Kajian literatur ini bertujuan untuk melihat harapan yang mempengaruhi keterlibatan pasien atau konsumen dalam konseling di Apotek.  Artikel pada kajian literatur ini menggunakan satu database yaitu Pubmed. Hasil pencarian dengan kombinasi kata kunci (community pharmacy) AND (counseling OR communication OR patient counseling factors OR patient participation) AND (patient expectations) menghasilkan 408 artikel yang memenuhi kriteria inklusi dalam kajian ini yaitu sebanyak 13 artikel. Hasil kajian literatur menunjukkan bahwa harapan yang mempengaruhi keterlibatan pasien atau konsumen dalam konseling di Apotek yaitu pemberian informasi yang baik dengan keterampilan komunikasi yang tepat, tata letak apotek dan hubungan apoteker atau staf apoteker dengan pasien baik, ramah dan sopan. Kata Kunci: Farmasi Komunitas, Konseling, Konseling Pasien, Harapan Pasien, Partisipasi Pasien
Laporan Kasus: Keamanan Kombinasi Terapi Nimodipine dan Nicardipine pada Pasien Cerebrovascular Accident Subarachnoid Hemorrhage (CVA SAH) Hayati, Syafira Nur; Badriah, Rani Nur; Widya, Reta Anggraeni; Pratama, Jainuri Erik; Setiadi, Antonius Adji Prayitno; Herawati, Fauna; Gondokesumo, Marisca Evalina
MAHESA : Malahayati Health Student Journal Vol 4, No 10 (2024): Volume 4 Nomor 10 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i10.15815

Abstract

ABSTRACT Hemorrhage stroke is caused by injury due to acute extravasation of blood into the brain parenchyma from rupture of small cerebral blood vessels. One of the etiologies of hemorrhage stroke is hypertension. Hypertension is a disease in which the blood pressure value exceeds normal, namely if the systolic blood pressure value is ≥ 140mmHg and/or the diastolic blood pressure value is ≥ 90mmHg. Giving calcium channel blocker drugs has good benefits. This research is a descriptive case study, namely describing the problem of the safety of using a combination of Nimodipine and Nicardipine therapy in Cerebrovascular Accident Subarachnoid Hemorrhage (CVA SAH) patients. Below we present a case of hypertension in a 59 year old female patient who was admitted to hospital with complaints of decreased consciousness, a history of diabetes mellitus, and a history of hypertension. The patient received combination therapy of Nicardipine (drip) 5-15mg and Nimodipine PO 4x60mg. For five days the patient was treated in hospital with the administration of two anti-hypertension drugs from the same class, namely the calcium channel blocker class. It can be seen from the patient's blood pressure profile that the patient's blood pressure tends to be stable so it is safe not to cause hypotension side effects that are harmful to the patient. Keywords: Case Report, Hypertension, Nimodipine, Nicardipine  ABSTRAK Stroke hemorrhage atau stroke perdarahan disebabkan oleh cedera karena ekstravasasi darah akut ke dalam parenkim otak dari pecahnya pembuluh darah otak kecil. Salah satu etiologi dari munculnya stroke hemorrhage adalah kondisi hipertensi. Hipertensi merupakan penyakit yang mana nilai tekanan darah melebihi normal, yaitu apabila nilai tekanan darah sistolik ≥ 140mmHg dan/atau nilai tekanan darah diastolik ≥ 90mmHg. Pemberian obat golongan calcium channel blocker memiliki manfaat yang baik. Penelitian ini merupakan studi kasus deskriptif mendeskripsikan kasus dari keamanan penggunaan kombinasi terapi Nimodipine dan Nicardipine pada pasien Cerebrovascular Accident Subarachnoid Hemorrhage (CVA SAH). Berikut ini kami presentasikan sebuah kasus hipertensi pada pasien perempuan berusia 59 tahun yang masuk rumah sakit dengan keluhan penurunan kesadaran, riwayat penyakit diabetes mellitus, dan riwayat penyakit hipertensi. Pasien mendapat terapi kombinasi Nicardipine (drip) 5-15mg dan Nimodipine PO 4x60mg. Selama lima hari pasien dirawat di rumah sakit dengan pemberian dua obat anti hipertensi dari golongan yang sama yaitu golongan calcium channel blocker, maka dapat dilihat dari profil tekanan darah pasien bahwa tekanan darah pasien cenderung stabil sehingga aman tidak menyebabkan munculnya efek samping hipotensi yang membahayakan pasien. Kata Kunci: Motivasi, Gaya Kepemimpinan, Perilaku Perawat, Sampah Medis
Knowledge On Drug Safety and Drug Utilization During Pregnancy: A Review of Systematic Reviews and Meta- Analyses Samudra, Anshar Timur; Setiadi, Antonius Adji Prayitno; Irawati, Sylvi
Malahayati Nursing Journal Vol 7, No 6 (2025): Volume 7 Nomor 6 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i6.20651

Abstract

ABSTRACT Drug use all through pregnancy can be beneficial or dangerous to the expectant mother, her fetus, and the baby. Some drugs have a risk of causing disability or death. Pregnant women's lack of knowledge about the harms of drug use during pregnancy can affect the use of these drugs during pregnancy. This study aims to review systematic reviews and meta-analyses regarding knowledge and use of medications during pregnancy in pregnant women. The design of this study is a scoping review using the PubMed database. The studies reviewed are systematic reviews and meta-analyses published in 2014-2024. Of the 1658 search results, five studies met the inclusion criteria. Four systematic reviews discussed drug utilization during pregnancy, and one systematic review addressed the knowledge of pregnant women regarding the use of drugs during pregnancy. The prevalence of antibiotic consumption during pregnancy ranges from 0.04 to 90%. While the prevalence of herbal medicine use in pregnant women varies between 12% and 93%. As many as 93.3% of pregnant women do not know enough about medicines and have gaps in knowledge or information about medicines, whether prescription drugs, over-the-counter drugs, or herbal medicines. Pregnant women's knowledge is also limited about the risks associated with polypharmacy in the first trimester of pregnancy, and there is a relationship between polypharmacy during pregnancy and an increased risk of congenital malformations. In conclusion, the prevalence of herbal medicine and antibiotic use during pregnancy is still relatively high. Most pregnant women do not have a good level of knowledge regarding the use of these medicines during pregnancy. Keywords: Drug Utilization, Knowledge, Pregnancy
Self-Medication Practices among University Students during the COVID-19 Pandemic Halim, Steven Victoria; Kumala, Stefany Marcellia; Sharifah, Fatichatus; Setiawan, Eko; Setiadi, Antonius Adji Prayitno
Sciences of Pharmacy Volume 4 Issue 4
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Self-medication is a treatment effort often undertaken by students, especially when the burden on healthcare services increases due to the coronavirus disease 2019 (COVID-19) pandemic. Nevertheless, up to five years after the onset of the global pandemic caused by the SARS-CoV-2 virus, no empirical evidence has been found to elucidate the self-medication practice among students in Indonesia. This observational study with a cross-sectional design aimed to identify students' self-medication practices at a university during the second wave of the COVID-19 pandemic. The research data was collected online using a questionnaire (Google Form). The questionnaire used consisted of two parts: student characteristics and student self-medication practices. A total of 1,019 students were involved in this study. The most used drugs for self-medication by students were vitamins/multivitamins (91.66%) and analgesics (64.57%). Most medicines used by students were obtained from pharmacies (88.71%), while information related to drugs was obtained from recommendations from friends and family members (72.72%). The primary consideration that prompted students to self-medicate during the COVID-19 era was the easy access to medicines (83.81%). Students' self-medication practices during a health service delivery crisis can be irrational. As this study was conducted within a single institution using a specific sampling approach, the findings should be regarded as context-specific rather than broadly generalizable.