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All Journal Jurnal Respirologi Indonesia Respiratory Science
Aniwidyaningsih, Wahju
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Health Professions Medicine & Pharmacology

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SUCCESSFUL TREATMENT OF ENDOBRONCHIAL TUBERCULOSIS IN PERSAHABATAN NATIONAL RESPIRATORY REFERRAL HOSPITAL Sari, Adistya; Aniwidyaningsih, Wahju; Burhan, Erlina
Jurnal Respirologi Indonesia Vol 40, No 2 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i2.102

Abstract

Backgrounds: Endobronchial tuberculosis (EBTB) is a special form of respiratory tuberculosis that continues to be a health problem because bronchostenosis may develop as a serious complication despite efficacious antituberculosis chemotherapy. The EBTB has nonspesific signs and symptoms, therefor it may cause misdiagnosis and delayed diagnosis. Persahabatan National Respiratory Referral Hospital doesn?t have data about successful treatment of EBTB Methods: This was a retrospective study of EBTB patients based from the medical record and confirm with bronchoscopy data from January 2013 to December 2017. Endobronchial tuberculosis diagnosed based from microbiology, histopathology examination or based on combination of clinical symptoms, radiology and bronchoscopy lesion appearance. Endobronchial tuberculosis treatment considered successful if there is improvement in clinical symptoms, microbiological conversion, accompanied by improvement or no change in the number of lesions or the radiological appearance. Results: The study sample consisted of 30 subjects. Majority of the subjects were female (86,7%), age
Positivity Rates of Histology Results Based on Lesion Size and Bronchus Sign in Lung Cancer Navratilova, Melfia; Aniwidyaningsih, Wahju; Soehardiman, Dicky; Prasenohadi, Prasenohadi; Alatas, Muhamad Fahmi; Elhidsi, Mia; Desiyanti, Ginanjar Arum; Reisa, Tina; Martini, Ni Putu Laksmi Ananda
Respiratory Science Vol. 5 No. 3 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i3.175

Abstract

Background: Lung cancer continues to be a major cause of cancer-related deaths globally. Bronchoscopy serves as a key diagnostic tool, allowing histological sampling through transbronchial biopsy (TBB). The bronchus sign, identified on pre-biopsy CT scans, is associated with improved diagnostic yield in TBB. Method: A retrospective study was conducted between October and December 2023 at Persahabatan Hospital, Jakarta, analyzing 88 patients suspected of lung cancer. Data collected comprised patient demographics, lesion size as determined by CT scans, and the presence or absence of the bronchus sign. Fisher’s exact test was applied for statistical analysis, with a predetermined significance level of P<0.05. Results: Positive histology results were identified in 38 cases (55.07%) for lesions ≥3 cm and 9 cases (47.39%) for <3 cm(P=0.607). In lesions ≥3 cm, the positivity rate was similar between those with the presence (55.81%) and absence (53.85%) of a bronchus sign (P>0.99). In lesions <3 cm, positivity was higher with a bronchus sign (60%) than without (25%) (P=0.55). Conclusion: The bronchus sign appears to increase TBB positivity, especially in peripheral lesions <3 cm. Lesion size also appears to influence TBB yield. However, the findings were not statistically significant, likely due to small sample size and missing CT data.
Dry Pleuroscopy as a Diagnostic Tool for Lung Cancer with Minimal Pleural Effusion Putra, Muhammad Ryan Adi; Aniwidyaningsih, Wahju; Martini, Ni Putu Laksmi Ananda
Respiratory Science Vol. 6 No. 1 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i1.178

Abstract

Dry pleuroscopy is a minimally invasive procedure used to evaluate and manage pleural conditions, particularly in cases of minimal pleural effusion (mini-PE) or dry pleural dissemination (DPD). This procedure involves the induction of artificial pneumothorax to create a workspace, allowing for direct access to the pleura without relying on a significant pleural effusion, unlike wet pleuroscopy. The key advantages of dry pleuroscopy include the elimination of the need for general anesthesia, mechanical ventilation, or specialized operating rooms, thereby reducing the risk of complications and associated costs. With a sensitivity of 94.4% and a specificity of 92.8%, dry pleuroscopy is highly effective for diagnosing lung cancer and pleural metastases in cases of minimal effusion. It also aids in lung cancer staging, minimizing the need for invasive procedures like lobectomy in complex cases. Artificial pneumothorax is a key step in dry pleuroscopy. It can be achieved through blunt dissection, optical trocars, or specialized tools such as the Boutin needle or Veress cannula. Ultrasound (USG) guidance further enhances procedural accuracy and safety by reducing complications. Dry pleuroscopy provides a safe, effective, and cost-efficient diagnostic and therapeutic solution, making it preferable to methods such as video-assisted thoracoscopic surgery (VATS), especially in patients unfit for invasive procedures.
Co-Authors Alatas, Muhamad Fahmi Desiyanti, Ginanjar Arum Elhidsi, Mia Erlina Burhan Martini, Ni Putu Laksmi Ananda Navratilova, Melfia Prasenohadi, Prasenohadi Putra, Muhammad Ryan Adi Reisa, Tina Sari, Adistya Soehardiman, Dicky