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All Journal Jurnal Respirologi Indonesia Jurnal Respirasi (JR) JURNAL PENELITIAN KEPERAWATAN MEDIK Respiratory Science
Soehardiman, Dicky
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Health Professions Medicine & Pharmacology Nursing Public Health

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Inflammatory Markers upon Admission as Predictors of Outcome in COVID-19 Patients Budhi Antariksa; Erlina Burhan; Agus Dwi Susanto; Mohamad Fahmi Alatas; Feni Fitriani Taufik; Dewi Yennita Sari; Dicky Soehardiman; Andika Chandra Putra; Erlang Samoedro; Ibrahim Nur Insan Putra Darmawan; Hera Afidjati; Muhammad Alkaff; Rita Rogayah
Jurnal Respirologi Indonesia Vol 41, No 4 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i4.185

Abstract

Background: Coronavirus disease 2019 (COVID-19) may cause dysregulation of the immune system, leading to hyperinflammation. Inflammatory markers can be used to predict in-hospital mortality in COVID-19 patients. This research was aimed to investigate the association between the levels of various inflammatory markers and mortality in COVID-19 patients.Methods: This study was conducted at Persahabatan National Respiratory Referral Hospital, Indonesia. Blood tests were performed upon admission, measuring the C-reactive protein, PCT, leukocyte, differential counts, and platelet count. The outcome measured was the mortality of hospitalized COVID-19 patients. Statistical analysis methods included the Mann–Whitney U test, receiver operating characteristic (ROC) analysis, and area under the curve (AUC) test.Results: Total 110 patients were included, and the laboratory values were analyzed to compare survivors and non-survivors. The non-survivor group had significantly higher leukocyte count, lower lymphocyte count, higher CRP and PCT levels, higher neutrophil-to-lymphocyte ratio (NLR), higher platelet-to-lymphocyte ratio (PLR), and lower lymphocyte-to-CRP ratio. As predictors of mortality, AUC analysis revealed that PCT, CRP, NLR, and PLR had AUCs of 0.867, 0.82, 0.791, and 0.746, respectively.Conclusions: Routine and affordable inflammatory markers tested on admission may be useful as predictors of in-hospital mortality in COVID-19 patients requiring hospitalization.
The Role of Bronchoscopic Cryoablation in Management of Central Airway Obstruction Dicky Soehardiman; Rahma Ayu Indahati; Mia Elhidsi
Jurnal Respirologi Indonesia Vol 41, No 1 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i1.154

Abstract

Central airway obstruction is one of respiratory emergency manifested as dyspnea, stridor and obstructive pneumonia. Most of central airway obstruction cases were treated with resection and surgery. Bronchoscopy is an initial modality to diagnose, stabilize the airway obstruction and evaluate for palliative treatment. Cryoablation is an evolving therapeutic bronchoscopic methods. Through rapid freeze–thaw cycles, cryoablation causes cell death and tissue necrosis or tissue adherence that can be used via the flexible or rigid bronchoscope. Cryoablation can safely restore airway patency and improve symptoms in patients with central airways obstruction from exophytic tumours. It is also used in the treatment of granulation tissue and benign strictures. Clinical studies showed improvement of dyspnea, cough, and hemoptysis with non-significant complications.
Lung Diffusion Capacity of X Fighter Pilot in Madiun Ririn Astuty Ningsih; Faisal Yunus; Triya Damayanti; Flora Ekasari; Sita Laksmi Andarini; Dicky Soehardiman; Ratnawati Ratnawati; Fathiyah Isbaniah; Erlang Samoedro
Jurnal Respirologi Indonesia Vol 40, No 1 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1007.037 KB) | DOI: 10.36497/jri.v40i1.96

Abstract

Background: Pilot works in the high environment that exposed by G force. Increasing G force led to linear decreases in cardiac output and blood oxygenation of the brain. Thus, likely due to decreased lung gas exchange capacity in hypergravity. This study aims to investigate the pulmonary diffusing capacity test among Fighter pilots in Madiun. Methods: This study used cross sectional method conducted on February 2019 in Madiun. The total subjects consist of 44 Fighter pilots based on total sampling. Interview was done to fill out question about sociodemografic and smoking habit, flight hour data and physical fitness. Lung function measurement was done using portable spirometry and DLCO equipment (Easyone TM Pro Lab). Result: Spirometri result was found in the standard normal range in 41 subjects (93,2%) only 3 subject (6,8%) get obstruction abnormalities and none of them get restriction result. Average VEP1 prediction was 103,3±10,60 % and median range for VEP1/KVP was 84,5(63,5-92,5) %. Lung diffusion capacity measurement was found to be normal in 41 subject (93,2%) and to be deficient in 3 subject (6,8%) in smoker. Conclusion: This study demosntrated that diffusion capacity and spirometry test in Fighter pilots generally in normal range. Lung diffusion capacity has no association with age, BMI, flight hour, physical fitness, Brinkman index and spirometry parameters. (J Respir Indo. 2020; 40(1): 39-47)
PENGGUNAAN KATETER INTRAPLEURA (WATER SEALED DRAINAGE, INDWELLING PLEURAL CATHETER, PIGTAIL CATHETER) PADA PENATALAKSANAAN KANKER PARU DENGAN EFUSI PLEURA MASIF Tamam Anugrah TAMSIL; Elisna SYAHRUDDIN; Dicky SOEHARDIMAN
Jurnal Penelitian Keperawatan Medik Vol 1 No 2 (2019): Jurnal Penelitian Keperawatan Medik
Publisher : Fakultas Keperawatan Institut Kesehatan Deli Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpkm.v1i2.115

Abstract

Massive pleural effusion is one of the problems in lung cancer treatment that cause death. The main treatment of cancer patient with massive pleural effusion is the placement of intrapleural catheter. This is a preliminary study which is aimed to assess tolerancies and efficacies of intrapleural catheter (WSD, IPC or pigtail catheter) in lung cancer with massive pleural effusion. This study is a retroscpective observational cohort study. Subjects are lung cancer patients with massive pleural effusion and catheterized with intrapleural catheter (WSD, IPC or pigtail catheter). The datas were taken from medical record at RSUP Persahabatan and assessed for tolerancies (acute or late complication) and efficacies ((length of hospital admission after catheter placement, duration and the reason of retraction) of intrapleural catheter. Tolerancies and efficacies of intrapleural catheter (WSD, IPC or pigtail catheter) in lung cancer patients with massive pleural effusion are quite good and safe. Prospective cohort studies are needed in the future to determine which type of intrapleural catheter is better for the treatment of massive pleural effusion in lung cancer patients.
Chest Wall Syndrome Isti Mardiana Soetartio; Agus Dwi Susanto; Dicky Soehardiman; Budhi Antariksa
Respiratory Science Vol. 2 No. 1 (2021): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i1.34

Abstract

Chest wall syndrome is the most frequent cause of chest pain complained by patients admitted to the physician’s office, in outward as well as in emergency department. It may affect all ages with sex ratio of 1:1 between man and woman. History of illness and sensibility to palpation or tenderness were the keys to the diagnostic approach. Pain was generally moderate, well localized, continuous or intermittent over a number of hours to days or weeks and was amplified by position or movement that was commonly located on the left side of the chest. Chest wall syndrome is usually a common and benign condition, but it leads to anxiety and frequent recurrence. Definitive treatment is not yet confirmed and treatment for the different condition causing isolated musculoskeletal chest pain is poor. Therefore, some options to avoid aggravating physical activities, stretching, and simple analgesics as needed are the best choices of current management.
Preparation and Findings in Diagnostic and Therapeutic Flexible Fiberoptic Bronchoscopy Procedures in Patients with COVID-19 Irandi Putra Pratomo; Hario Baskoro; Dicky Soehardiman; Prasenohadi Prasenohadi; Tutug Kinasih; Ahmad Fauzi; Ike Maretta; Nachita Putri; Kentaro Tokumo
Jurnal Respirasi Vol. 9 No. 1 (2023): January 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.1.2023.72-79

Abstract

The coronavirus disease 2019 (COVID-19), which has raised concerns about infection control for every clinical procedure, including flexible fiberoptic bronchoscopy (FFB), has drawn the attention of clinicians across the globe. A pulmonologist frequently conducts this procedure to diagnose and treat pulmonary diseases like COVID-19. This procedure involves direct airway observation and generates aerosol from the patient. However, it is considered a double-edged sword, as the risk of infection and instrument contamination always haunts its clinical benefit to the patients and the operators. Therefore, a guideline for preparing and indicating FFB in COVID-19 must be addressed appropriately by emphasizing the importance of infection prevention and control. Fortunately, several recommendations and findings have emerged over the past three years, which should support safe FFB procedures for its operators with controlled infection. This study summarizes the indication, objective, contraindication, risk, preparation, and findings in diagnostic and therapeutic FFB patients with COVID-19.
The Evolution of Transbronchial Lung Biopsy Guidance Alatas, Mohammad Fahmi; Bies, Asri Liqditta; Prasenohadi, Prasenohadi; Soehardiman, Dicky; Aniwdyaningsih, Wahju; Elhidsi, Mia; Desianti, Ginanjar Arum; Reisa, Tina; Rasmin, Menaldi
Respiratory Science Vol. 5 No. 2 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i2.170

Abstract

Histological confirmation of lung lesions is necessary prior to determining further management. Imaging preparation is needed to find the biopsy site such as a computed tomography scan. Imaging helps to trace the position of lung lesions that are peripheral and not visualized by bronchoscope. However, along with the discovery of small lesions and peripheral location, two-dimensional imaging alone remains suboptimal. Therefore, to reach lung lesions peripherally would need to a guide through the bronchial. Subsequently, the method of guiding transbronchial biopsy evolved. Namely, real-time fluoroscopy, radial-probe endobronchial ultrasound, virtual bronchoscopy navigation and electromagnetic bronchoscopy navigation are guiding modalities with each of their advantages and disadvantages. Several biopsy modalities are used in combination to increase the accuracy of diagnosis. Careful analysis in planning and an understanding of the limitations and advantages of diagnostic modalities must be considered in deciding which method to choose.
Positivity Rates of Histology Results Based on Lesion Size and Bronchus Sign in Lung Cancer Navratilova, Melfia; Aniwidyaningsih, Wahju; Soehardiman, Dicky; Prasenohadi, Prasenohadi; Alatas, Muhamad Fahmi; Elhidsi, Mia; Desiyanti, Ginanjar Arum; Reisa, Tina; Martini, Ni Putu Laksmi Ananda
Respiratory Science Vol. 5 No. 3 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i3.175

Abstract

Background: Lung cancer continues to be a major cause of cancer-related deaths globally. Bronchoscopy serves as a key diagnostic tool, allowing histological sampling through transbronchial biopsy (TBB). The bronchus sign, identified on pre-biopsy CT scans, is associated with improved diagnostic yield in TBB. Method: A retrospective study was conducted between October and December 2023 at Persahabatan Hospital, Jakarta, analyzing 88 patients suspected of lung cancer. Data collected comprised patient demographics, lesion size as determined by CT scans, and the presence or absence of the bronchus sign. Fisher’s exact test was applied for statistical analysis, with a predetermined significance level of P<0.05. Results: Positive histology results were identified in 38 cases (55.07%) for lesions ≥3 cm and 9 cases (47.39%) for <3 cm(P=0.607). In lesions ≥3 cm, the positivity rate was similar between those with the presence (55.81%) and absence (53.85%) of a bronchus sign (P>0.99). In lesions <3 cm, positivity was higher with a bronchus sign (60%) than without (25%) (P=0.55). Conclusion: The bronchus sign appears to increase TBB positivity, especially in peripheral lesions <3 cm. Lesion size also appears to influence TBB yield. However, the findings were not statistically significant, likely due to small sample size and missing CT data.
Bronchial Artery Embolization in Hemoptysis Audina, Dea Putri; Isbaniah, Fathiyah; Soehardiman, Dicky; Darwis, Andi; Amien, Bagus Radityo
Jurnal Respirasi Vol. 11 No. 2 (2025): May 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.2.2025.174-182

Abstract

Hemoptysis, characterized by bleeding from the lower airways, is classified as mild, moderate, or massive, with massive hemoptysis carrying a mortality rate of 6.5–38%. Tuberculosis (TB) remains the most common cause globally. Management strategies include invasive and noninvasive options, with bronchial artery embolization (BAE) emerging as a cornerstone of noninvasive treatment since its introduction in the 1970s. Bronchial artery embolization provides rapid bleeding control and high success rates for both short- and long-term outcomes. Despite these advantages, recurrence rates range widely from 10–55%, often due to incomplete embolization, vessel recanalization, and collateral vessel development. The procedure employs embolic agents such as polyvinyl alcohol (PVA) particles, gelatin sponges, and tris-acryl gelatin microspheres, with minimal complications such as spinal cord infarction or broncho-esophageal fistulas. Diagnostic tools like computed tomography (CT) and bronchoscopy complement BAE by localizing the bleeding sites, stabilizing the airway, and aiding in definitive management. Bronchoscopy serves diagnostic and therapeutic purposes, employing techniques such as vasoconstrictor instillation, laser therapy, and balloon tamponade to control bleeding. Bronchial artery embolization is particularly effective for patients with life-threatening or recurrent hemoptysis who are unsuitable for surgery, often acting as a bridge to elective interventions. This literature review highlighted the pathophysiology, diagnostic modalities, BAE techniques, outcomes, and challenges involved in managing hemoptysis, emphasizing the role of BAE as a vital, minimally invasive therapeutic option.
Correlation Between Predicted Maximal Oxygen Uptake (VO2 max) from The Six-Minute Walk Test and Reaction Time in Male Security Guards Noor, Amira Ismi; Soehardiman, Dicky; Taufik, Feni Fitriani
Jurnal Respirologi Indonesia Vol 45 No 4 (2025)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v45i4.1015

Abstract

Background: Reaction time, the interval between stimulus and motor response, reflects alertness and is critical in professions such as security guards. Maximal oxygen uptake (VO₂ max), a standard measure of cardiorespiratory fitness, has been linked to improvements in cognitive performance. This study examined the relationship between predicted VO2 max values from the six-minute walk test and reaction time in security guards. Methods: A cross-sectional study was conducted among 33 male security guards at Persahabatan National Respiratory Center between October and November 2024. Participants completed physical activity questionnaires, the six-minute walk test, and audio-visual reaction time assessments. Results: The mean predicted VO2 max was 18.3±2.9 ml/kg/min (metabolic equivalents/METs: 5.2±0.8). Body mass index significantly influenced VO₂ max (p = 0.002). Auditory reaction time was significantly faster than visual reaction time (172.6±25.7 ms vs. 199.8±33.1 ms, p < 0.001). A weak negative correlation was found between predicted VO₂ max and visual reaction time (r = –0.340, p = 0.048), but not with auditory reaction time (r = –0.245, p = 0.169). Conclusion: Higher cardiorespiratory fitness, as reflected by predicted VO₂ max, was not strongly associated with visual reaction time among security guards.
Co-Authors Agus Dwi Susanto Ahmad Fauzi Alatas, Mohammad Fahmi Alatas, Muhamad Fahmi Amien, Bagus Radityo Aniwdyaningsih, Wahju Aniwidyaningsih, Wahju Audina, Dea Putri Bies, Asri Liqditta Budhi Antariksa Darwis, Andi Desianti, Ginanjar Arum Desiyanti, Ginanjar Arum Dewi Yennita Sari Elhidsi, Mia Elisna Syahruddin Erlina Burhan Faisal Yunus Flora Ekasari Hario Baskoro Hera Afidjati Ibrahim Nur Insan Putra Darmawan Ike Maretta Irandi Putra Pratomo Isbaniah, Fathiyah Isti Mardiana Soetartio Kentaro Tokumo Martini, Ni Putu Laksmi Ananda Menaldi Rasmin Mia Elhidsi Mohamad Fahmi Alatas Muhammad Alkaff Nachita Putri Navratilova, Melfia Noor, Amira Ismi Prasenohadi Prasenohadi Prasenohadi, Prasenohadi Putra, Andika Chandra Rahma Ayu Indahati Ratnawati Ratnawati Reisa, Tina Ririn Astuty Ningsih Rita Rogayah Samoedro, Erlang Sita Laksmi Andarini Tamam Anugrah TAMSIL Taufik, Feni Fitriani Triya Damayanti Tutug Kinasih