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All Journal Buletin Ilmiah Nagari Membangun Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Kefarmasian Indonesia
Srangenge, Yoneta
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Agriculture, Biological Sciences & Forestry Humanities Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Pengaruh Penghambatan Enzim Siklooksigenase-2 dan Aktivitas Antiinflamasi dari Ekstrak Daun Ketumbar (Coriandrum sativum L.) Ifora, Ifora; Sintia, Bella; Srangenge, Yoneta
Jurnal Kefarmasian Indonesia VOLUME 11, NOMOR 1, FEBRUARI 2021
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v11i1.3487

Abstract

Inflammation is a normal protective response to tissue damage that mediated by Cyclooxygenase-2 (COX-2) enzyme. The enhancement incidence and impact of inflammatory diseases have encouraged the search for new pharmacological strategies to overcome the problem. Ketumbar (Coriandrumsativum L.) has been traditionally used as an anti-inflammatory and antioxidant, thus giving chance for anti-inflammatory studies. This study aims to determine the ethanol extract of Ketumbar (Coriandrumsativum L.) leaves anti-inflammatory activity and inhibitory effect on COX-2 enzyme. This study uses male wistar rats with 180–220 g body weights. The rats is divided into six groups by the dose of 125 mg/kg BW, 250 mg/kg BW, and 500 mg/kg BW; positive control (Carrageenan 1%); negative control (Na. CMC 0,5%); and comparative group (Celecoxib 9 mg/kg BW). Determining the anti-inflammatory activity, the oedema formation is measured using a plethysmometer and the inhibition activity is determined by ELISA methods. The results showed that the ethanol extract of Ketumbar leaves by the dose of 125 mg/kg BW, 250 mg/kg BW, and 500 mg/kg BW was significantly inhibitted COX-2 valued 65,61%, 76,83%, and 62,93%. The anti-inflammatory activity was shown by inhibiting oedema valued of 62.26%, 70.59%, and 54.90% respectively. These findings suggested that the ethanol extract of Ketumbar leaves had anti-inflammatory activity, that was possibly mediated through inhibition of COX-2 enzymes
EDUKASI PENYULUHAN OBAT DAN PENGOBATAN GRATIS BAGI MASYARAKAT DI DESA PERKAMPUNGAN ADAT SIJUNJUNG Dillasamola, Dwisari; Srangenge, Yoneta; Ardiansyah, Aan; Aldi, Yufri; Wahyuni, Fatma Sri; Husni, Elidahanum; Abdillah, Rahmad; Julmiza, Adinny; Benardo, Benardo
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 7 No. 2 (2024)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i2.600

Abstract

Community health education is crucial, including education on the rational use of antibiotics, as well as halal food and medicine. Additionally, providing free medical treatment has a significant impact, encouraging the community to prioritize health and maintain it as a primary concern. This community service project was conducted in the Desa Perkampungan Adat Sijunjung. The objective of this activity is to maintain and improve the community's health status. One way to achieve this is through community service activities. The service involved educational sessions on medicines and health, as well as free medical treatment, in collaboration with the Faculty of Pharmacy and the Faculty of Medicine at Universitas Andalas. The education targeted pregnant women and the elderly, focusing on proper medication selection, rational use of antibiotics, and education on halal medicines and food. Free medical treatment involved specialist doctors and pharmacists, who also provided counseling on medications to patients. The results of the activity showed high community enthusiasm, with more than 100 prescriptions filled. The education on the rational use of medications, particularly antibiotics, is expected to increase community awareness and knowledge. This activity also highlights the importance of pharmacists in providing patient-oriented pharmaceutical services, as well as the importance of promotional and preventive efforts in maintaining public health. It can be concluded that free medical treatment is expected to encourage the community to be more health-conscious and less fearful of seeking medical care.
Utilization of Unprocessed Sugarcane Bagasse and Coffee Waste into Soap Products Rachmaini, Fitri; Abdillah, Rahmad; Gumala, Azhoma; Srangenge, Yoneta
Warta Pengabdian Andalas Vol 32 No 4 (2025)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.32.04.473-479.2025

Abstract

The increasing by-products from sugarcane and coffee consumption have resulted in a greater volume of sugarcane bagasse and coffee waste with potential environmental impacts. Physically and chemically, coffee and sugarcane waste can be processed into soap products without further processing. This community service activity aimed to provide education and practical skills in utilising coffee and sugarcane waste as raw materials for hand soap production. The activity was conducted at the Baitussalam Mosque in Gadut, Padang City, with 20 participants. The implementation methods included material presentation, demonstrations, and hands-on practice in liquid soap formulation. The soap formula used sugarcane and coffee waste as the main ingredients with additional components including Texapon as a surfactant, EDTA as a chelating agent, salt as a viscosity regulator, warm water, and fragrance. The findings indicated that participants comprehended the potential of utilising sugarcane and coffee waste, allowing them to produce a basic liquid soap product for daily usage. Soap made from sugarcane and coffee waste has the potential to become an organic product with antioxidant and antimicrobial benefits for the skin. This activity aims to increase public awareness of the importance of waste management and promote the development of environmentally friendly, nature-based creative enterprises.
Co-Authors Ardiansyah, Aan Azhoma Gumala Benardo, Benardo Dwisari Dillasamola Fatma Sri Wahyuni Ifora, Ifora Julmiza, Adinny Rachmaini, Fitri Rahmad Abdillah Sintia, Bella Yufri Aldi