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Ekstrak Teh Hijau Mengurangi Luas Area Fibrosis Paru Tikus Desdiani; Iris Rengganis; Samsuridjal Djauzi; Agus Setiyono; Mohammad Sadikin; Sri Widia A. Jusman; Nurjati Chairani Siregar; Suradi; Putri C. Eyanoer
Majalah Patologi Indonesia Vol 29 No 1 (2020): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Indonesia (IAPI)

BackgroundPulmonary fibrosis is often found in infectious diseases and chemical exposure in the work environment. Antifibrotic effects can befibropreventive and fibrolysis. Bleomycin can cause inflammation and pulmonary fibrosis. Catechin is proven can repair liverdamages due to alcohol induction. The aim of this study is to examine the effect of antifibrotic green tea catechin on reducing thearea of rat lung fibrotic.MethodsThis research was carried out in vivo experimentally in the Laboratory Animal Management Unit at Faculty of Veterinary MedicineIPB in 4 groups of rat experiments, consisting of 3 rats in the negative control group, 3 rats in the positive control group, 3 rats in thegroup of rats given bleomycin on the 8th day and 28thwith green tea extract every day from day 0 to 49 days (fibropreventive), 3groups of rats given bleomycin days 0 and 21 with green tea extract every day from day 15 to 49 (fibrolysis). Histopathologicalexamination was performe for all groups of rats.ResultsThis study showed that administration of green tea extract in fibropreventive groups and fibrolysis groups could reduce the fibrosisarea in rat lungs based on Aschroft's modified scale.ConclusionBased on the results of this study it was found that the anti-fibrotic activity of green tea extract was proven to be able to suppressthe development of pulmonary fibrosis both by fibropreventive and fibrolysis

Pengaruh Strategi Dan Praktik Supply Chain Management Terhadap Kinerja Operasional Perusahaan (Studi Kasus : Beton Precast dan Readymix di Daerah Banten) Andi Maddeppungeng; Desdiani Desdiani; Wiguna Mangun Kusuma
Jurnal Fondasi Vol 8, No 2 (2019)
Publisher : JURUSAN TEKNIK SIPIL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36055/jft.v8i2.7335

Pembangunan infrastruktur yang begitu masif membuat permintaan akan material konstruksi terus bertumbuh tidak terkecuali beton precast dan readymix. Penelitian ini bertujuan untuk menganalisis pengaruh strategi supply chain management (SCM) terhadap praktik perusahaan beton precast dan readymix, menganalisis pengaruh strategi SCM terhadap kinerja operasional perusahaan beton precast dan readymix, menganalisis pengaruh praktik SCM terhadap kinerja operasional perusahaan beton precast dan readymix. Penelitian ini merupakan eksplantori dengan pengolahan data Smart PLS 3.2.8 (30 Day Trial) SEM untuk mengevaluasi outer model dan inner model. Penelitian dilakukan pada 100 pekerja dari 4 perusahaan beton precast dan readymix diwilayah Banten menggunakan teknik stratified random sampling.Dari hasil penelitian menunjukan terdapat pengaruh antara strategi SCM terhadap praktik SCM sebesar 64,5 %, terdapat pengaruh antara strategi SCM terhadap kinerja operasional sebesar 42,1 %, terdapat pengaruh antara strategi SCM terhadap kinerja operasional melalui praktik SCM sebesar 64,9 %.

Analisis Risiko Biaya Dan Waktu pada Pelaksanaan Pekerjaan Struktur Atas Proyek Gedung Bertingkat Tinggi (Studi Kasus: Proyek Bangunan Gedung Bertingkat Tinggi di DKI Jakarta dan Sekitarnya) Andi Maddeppungeng; Desdiani Desdiani; Rikza Afa Aditya
Jurnal Fondasi Vol 8, No 2 (2019)
Publisher : JURUSAN TEKNIK SIPIL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36055/jft.v8i2.7347

Pengelolaan risiko pada proyek konstruksi gedung bertingkat tinggi sangat penting dilakukan. Dikarenakan proyek bangunan gedung bertingkat tinggi dapat dikatakan memiliki risiko tinggi karena bobot pekerjaan dan tingginya struktur yang akan dibangun. Semakin tinggi gedung yang akan dibangun, maka semakin tinggi pula tingkat risiko pekerjaannya. Maka dari itu, risiko dari suatu kegiatan proyek khususnya gedung bertingkat tinggi perlu dikelola dengan tepat.Jenis penelitian yang digunakan adalah eksplanatori. Sebuah penelitian eksplanatori merupakan penelitian yang menjelaskan hubungan kausal antara variabel penelitian dengan pengujian hipotesis. Di dalam penelitian eksplanatori, pendekatan yang dipakai dalam penelitian ini adalah metode survei dengan menggunakan kuisioner. Untuk analisis data dilakukan dengan menggunakan proses analisis hirarki dibantu dengan SPSS ver. 25 dan Ms. Excel 2016Hasil penelitian menunjukkan bahwa “Terjadinya Angin Kencang” (X3) menjadi risiko paling dominan terhadap kinerja biaya dan waktu pelaksaan pekerjaan struktur atas proyek gedung bertingkat tinggi. Dengan pengaruh terhadap biaya yaitu adanya biaya tambah akibat pekerjaan yang tertunda, dan pengaruh terhadap waktu yaitu terjadinya penambahan waktu pelaksanaan dikarenakan beberapa pekerjaan luar ruangan harus tertunda

PREVALENCE AND CLINICAL CHARACTERISTICS OF ALLERGIC RHINITIS AMONG ASTHMATIC PATIENTS IN THE EMERGENCY DEPARTMENT OF A BHAYANGKARA BRIMOB HOSPITAL IN INDONESIA: PREVALENSI DAN KARAKTERISTIK KLINIS RINITIS ALERGI PADA PASIEN ASMA DI INSTALASI GAWAT DARURAT RUMAH SAKIT BHAYANGKARA BRIMOB DI INDONESIA Winugroho, Mohammad Lukmanul Hakim; Kemuning, Asri Ragil; Rusmajati, Jetty; Desdiani
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Vol. 24 No. 2 (2025): Juli 2025
Publisher : Faculty of Medicine Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/ibnusina.v24i2.930

Introduction: Asthma and allergic rhinitis frequently coexist. Objective: This study aims to characterize adult asthma patients who visited the emergency department (ED) and had allergic rhinitis between June 2023 and December 2024 at Bhayangkara Hospital, Depok City, West Java. Methods: This retrospective study analyzed 144 asthma patients who visited the ED during the specified period. The cohort included 89 females and 55 males. Diagnoses of bronchial Asthma and allergic rhinitis were confirmed through clinical history and physical examination by the attending physician, and all data is obtained from the patient's medical records. Results: Among the study population, 66.66% had coexisting asthma and allergic rhinitis. The majority were female and aged between 18 and 44 years. Chest X-rays revealed no significant abnormalities. Asthma prevalence was higher in females (61.8%) than males (38.19%), with a mean age of 32.53 years. A history of atopy, encompassing conditions like eczema, food allergies, and eye inflammation, was prevalent among 46.52% of patients. Smoking habits varied, with 74.3% being ex-smokers or non-smokers, while 25.69% were current smokers. Passive smoke exposure was noted in 37.5%, and 7.63% had exposure to biomass fuel. About 88.19% of emergency patients visits were classified as moderate asthma attacks, with 66.93% of these patients also having allergic rhinitis. Severe asthma attacks occurred in 11.8% of cases, with 58.82% of these patients also suffering from allergic rhinitis. Conclusions: The high prevalence of allergic rhinitis among asthma patients emphasizes the necessity of early diagnosis and good management to optimize patient outcomes.

Ekstrak Teh Hijau Mengurangi Luas Area Fibrosis Paru Tikus Desdiani; Iris Rengganis; Samsuridjal Djauzi; Agus Setiyono; Mohammad Sadikin; Sri Widia A. Jusman; Nurjati Chairani Siregar; Suradi; Putri C. Eyanoer
Majalah Patologi Indonesia Vol. 29 No. 1 (2020): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v29i1.403

BackgroundPulmonary fibrosis is often found in infectious diseases and chemical exposure in the work environment. Antifibrotic effects can befibropreventive and fibrolysis. Bleomycin can cause inflammation and pulmonary fibrosis. Catechin is proven can repair liverdamages due to alcohol induction. The aim of this study is to examine the effect of antifibrotic green tea catechin on reducing thearea of rat lung fibrotic.MethodsThis research was carried out in vivo experimentally in the Laboratory Animal Management Unit at Faculty of Veterinary MedicineIPB in 4 groups of rat experiments, consisting of 3 rats in the negative control group, 3 rats in the positive control group, 3 rats in thegroup of rats given bleomycin on the 8th day and 28thwith green tea extract every day from day 0 to 49 days (fibropreventive), 3groups of rats given bleomycin days 0 and 21 with green tea extract every day from day 15 to 49 (fibrolysis). Histopathologicalexamination was performe for all groups of rats.ResultsThis study showed that administration of green tea extract in fibropreventive groups and fibrolysis groups could reduce the fibrosisarea in rat lungs based on Aschroft's modified scale.ConclusionBased on the results of this study it was found that the anti-fibrotic activity of green tea extract was proven to be able to suppressthe development of pulmonary fibrosis both by fibropreventive and fibrolysis

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