Article Per Year (5 Year)
p-Index From 2021 - 2026
1.94
P-Index
This Author published in this journals
All Journal Resona : Jurnal Ilmiah Pengabdian Masyarakat JOPS (Journal Of Pharmacy and Science) Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat JURNAL BIOSAINSTEK Jurnal Abdi Insani Jurnal Mandala Pengabdian Masyarakat Jurnal Farmasi Tinctura Jurnal Kesehatan Farmasi Jurnal Farmasi Indonesia Jurnal Sains dan Kesehatan
Eri Marwati
Prodi Farmasi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Khairun
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 11 Documents
Search

 1   2 
Aktivitas Antioksidan Ekstrak Etanol Daun Jarak Pagar (Jatropha curcas L.) Melalui Metode FRAP dan Penambatan Molekuler Sadik, Fahmi; Marwati, Eri
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 16 No. 2 (2024): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v16i2.294

Abstract

This study evaluated the antioxidant activity of Jatropha curcas L. leaf ethanol extract via Ferric Reducing Antioxidant Power (FRAP) assay and molecular docking against Superoxide Dismutase 1 (SOD1) enzyme. Extraction was performed by maceration using 96% ethanol. In vitro results showed the extract possessed moderate antioxidant capacity of 3.52 mg TE/g and contained flavonoids and tannins. In silico analysis revealed that Naringenin-7-O-β-D-glucopyranoside exhibited the highest binding affinity towards SOD1 with a Gibbs free energy of -10.41 kcal/mol, surpassing the co-crystal ligand (-9.05 kcal/mol). Stable interactions were formed through hydrogen bonds at key residues LYS175 and TRP109. This study concludes that J. curcas leaves have dual potential as electron donors and modulators of body defense enzymes for combating oxidative stress.
Co-Authors Abulkhair Abdullah Amran Nur Bambang Tjiroso Bambang Tjiroso Bambang Tjiroso, Bambang Didik Kurniawan Ermalyanti Fiskia Muh Nasir Nindya Prisma Dewi Nurfadilah, Nadia Risaldi Abas Sadik, Fahmi