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All Journal The Journal of Society Medicine (JSOCMED)
Hutagalung, Haflin Soraya
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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The Association Between Degree of Severity and Number of Medications with Quality of Life in Parkinson's Disease Patients Heidiyana, Marisa; Surbakti, Khairul Putra; Hutagalung, Haflin Soraya
Journal of Society Medicine Vol. 2 No. 4 (2023): April
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i4.48

Abstract

Introduction: Quality of life is an important parameter to be assessed, especially in progressive chronic diseases such as patients with Parkinson's Disease (PD). Parkinson's Disease Questionnaire-39 (PDQ-39) is the most widely used measurement tool in assessing the quality of life of PD patients. In PD, a series of features can affect the quality of life including the degree of disease severity and the number of medications. The aim of this study is to determine the relationship between the severity of the disease and the number of medications with the quality of life of people with PD so that it is hoped that it can help improve the quality of life of PD patients. Method: This study used a cross-sectional design. The research subjects were PD patients at the Neurology Polyclinic at Haji Adam Malik Hospital Medan from April - November 2020 who met the inclusion criteria. Assessing the severity of the disease using the Hoehn and Yahr and measuring the quality of life using the PDQ 39. Data analysis used the Spearman correlation test for the degree of severity and the Mann- Whitney test for the number of medications. Results: Of the 47 subjects who met the inclusion criteria, most were males (68.1%), with a mean age of 64.82 ± 9.52 years old, with University graduates as the majority of education level (46.8%) and the civil servant as the majority of a profession (34.0%). Stage 2 on Hoehn and Yahr Scales is the most common severity level of disease (55.3%), and polytherapy is the majority of the number of medications (74.5%). The median value of quality of life is 35, with the lowest score being 10 and the highest score being 98. From the results of the bivariate analysis, it was found that there was a very strong, significant association between the degree of disease severity and the quality of life (p <0.001 r=0.872), and there was a significant difference between the number of medications with the quality of life of Parkinson's disease patients (p=0.041). Conclusion: There is a very strong association between the degree of severity and the quality of life of people with Parkinson's disease and there is a difference in the quality of life of PD patients between those who receive monotherapy and polytherapy so there is an effect of the number of medication given on the quality of life of Parkinson's disease patients.
Relationship between Homeostatic Model Assessment for Insulin Resistance and Waist Hip Ratio with Cognitive Function in Type 2 Diabetes Mellitus Fitri, Fasihah Irfani; Novita, Oriza; Hutagalung, Haflin Soraya
Journal of Society Medicine Vol. 2 No. 7 (2023): July
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i7.60

Abstract

Introduction: Cognitive impairment is a common complication of Type 2 Diabetes Mellitus (T2DM) in which the underlying mechanism are insulin resistance and associated central obesity. Homeostatic model assessment of insulin resistance (HOMA-IR) and waist-hip ratio (WHR) have been used as markers for insulin resistance and central obesity, respectively, but their direct association with cognition remains unclear. This study was conducted to determine the relationship between HOMA-IR and WHR with cognitive function in T2DM patients. Method: This was a correlative analytic study with a cross sectional design involving T2DM pateints. The HOMA-IR was assessed based on blood laboratory results, the WHR was measured by dividing circumference of the waist by the circumference of the hips and cognitive function was assessed using the Montreal Cognitive Assessment Indonesian Version (MoCA-INA). Results: : There were 56 patients included in the study. There was no significant relationship between HOMA-IR and cognitive function in T2DM patients (p=0.276; r=0.148). There was also no significant relationship between WHR and cognitive function (p = 0.499; r = 0.092). Conclusion: The HOMA-IR and WHR were not correlated with cognitive function in T2DM.
Association between Clinical Stage of HIV and Peripheral Sensory Neuropathy Sibarani, Riris; Fitri, Aida; Hutagalung, Haflin Soraya
Journal of Society Medicine Vol. 3 No. 1 (2024): January
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i1.119

Abstract

Introduction: Several factors that contributed in the incidence of peripheral sensory neuropathy in HIV patients, including the number of Cluster of Differentiation 4 (CD4) lymphocytes, high HIV viral load, opportunistic infections and clinical stage of HIV.5 The aim of this study was to analyze the association between clinical stage of HIV to peripheral sensory neuropathy. Method: This research was a descriptive study with a cross-sectional design, conducted in General Hospital of Haji Adam Malik Medan during June to October 2023. Brief Peripheral Neuropathy Screening tool validated by AIDs Clinical trial group was used for screening peripheral sensory neuropathy. The variable to be analyzed in this study was clinical stage of HIV disease. Research data were analyzed using the SPSS (Statistical Product and Science Service) program for Windows, version 26. Univariate, bivariate, and multivariate analyses were conducted. Univariate analysis aimed to obtain the characteristics of the study subjects. The chi square test was used to determine the association between clinical stage of HIV to peripheral sensory neuropathy. Results: There were 83 subjects eligible for this study, in which 62,7% were males, with the mean age of the patients was 39,4+9,6 years. A total of 47 subjects (56.6%) were stage III and 36 subjects (43.4%) were stage IV. There was a significant association between clinical stage of HIV and peripheral sensory neuropathy in HIV positive patients with p value <0.001. Conclusion: There was a significant association between clinical stage of HIV to sensory peripheral neuropathy.
Factors Affecting Malnutrition in Parkinson's Disease Patients Using Mini Nutritional Assessment at H. Adam Malik Hospital and Network Hospitals Dwi Putri, Sabrina; Kadri, Alfansuri; Hutagalung, Haflin Soraya
Journal of Society Medicine Vol. 3 No. 11 (2024): November
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i11.174

Abstract

Introduction: Parkinson's Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of motor control due to the degeneration of dopamine neurons in the brain and the formation of Lewy bodies. The exact cause of PD is still unknown, but factors such as free radicals, mitochondrial dysfunction, and protein degradation are believed to play a role. To identify the factors that influence malnutrition in patients with Parkinson's disease. Method: This study is an observational analytical study with a cross-sectional design, conducted at RSUP H. Adam Malik Medan and its hospital network. The subjects were 45 Parkinson's patients selected consecutively from March to June 2024. The data in this study used primary data using the Mini Nutritional Assessment (MNA) questionnaire obtained from anamnesis, physical examination and nutritional status examination using body weight, height, calf circumference and upper arm circumference. Results: Statistical analysis showed no significant results between gender, therapy regimen, and symptoms such as bradykinesia, rigidity, hyposmia, and dysphagia on malnutrition with values of p = 0.157, p = 0.377, p = 0.173, p = 0.173, p = 0.264, and p = 0.154, respectively. However, the results of the statistical analysis showed significant results between age and malnutrition with a p-value of 0.003 and a substantial relationship between disease duration, severity, and symptoms such as postural instability and constipation on malnutrition with the same p-value of p <0.001. Conclusion: There was an association between age, disease duration, severity, and symptoms such as postural instability and constipation in Parkinson's disease patients with malnutrition status.
Relationship Between Sleep Quality and Primary Headache Among Employees of PT. Valeo Ac Indonesia Simanjuntak, Harel Mega Serafine; Hutagalung, Haflin Soraya; Indri Adriztina; Sri Amelia
Journal of Society Medicine Vol. 3 No. 12 (2024): December
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v3i12.186

Abstract

Introduction: Primary headaches, including migraines and tension-type headaches (TTH), are characterized by pain in the head without any underlying health issues. Poor sleep quality is a significant factor contributing to the occurrence of these headaches. Despite the prevalence of these conditions, many individuals neglect them and fail to seek appropriate treatment. This study analyzed the relationship between sleep quality and primary headache. Methods: This analytical research utilized a cross-sectional approach. Primary data were collected directly from respondents using two validated questionnaires: the Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality and the Headache Screening Questionnaire (HSQ) to identify primary headache characteristics. The study included 92 employees of PT. Valeo AC Indonesia as respondents. Results: Among the 92 subjects, 32.6% were found to have poor sleep quality, while 35.9% experienced primary headaches. Tension-type headaches (TTH) were identified as the most common type of primary headache. Primary headaches were predominantly reported by individuals aged <30 years, male respondents, and those who were married. Bivariate analysis revealed a significant relationship between poor sleep quality and the occurrence of primary headaches, with a p-value of 0.015, indicating statistical significance. Conclusion: This study demonstrates a significant relationship between sleep quality and the prevalence of primary headaches among employees of PT. Valeo AC Indonesia. These findings highlight the importance of improving sleep quality as a potential strategy to reduce the occurrence of primary headaches, particularly among at-risk populations.
Co-Authors Dwi Putri, Sabrina Fitri, Aida Fitri, Fasihah Irfani Heidiyana, Marisa Indri Adriztina Kadri, Alfansuri Novita, Oriza Sibarani, Riris Simanjuntak, Harel Mega Serafine Sri Amelia Surbakti, Khairul Putra