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Sudjarwo, Indrati
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The effectiveness of propolis on the healing period of recurrent aphthous stomatitis Han, Foo You; Setiadhi, Riani; Sudjarwo, Indrati
Padjadjaran Journal of Dentistry Vol 24, No 3 (2012): November 2012
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol24no3.26844

Abstract

Introduction: Propolis®, also known as bee glue, is a substance acquired from the bee hive, which contain antimicrobial, antiviral and antifungal properties. The aim of this research was to identify the best concentration of propolis® that is effective for healing period of Recurrent Aphthous Stomatitis (RAS). Methods: This research was experimental study and the sample are patients who have Recurrent Aphthous Stomatitis during the extent of the research at Rumah Sakit Gigi dan Mulut, Bandung, Indonesia. the patients were given Propolis® of either 0.5% or 1.0% concentration randomly. Results: Using the Kolmogorov-Smirnov test, the data is tested for normality of patients whom are applying Propolis® cream at concentration of 0.5% and 1%. The average time taken for the subject with 0.5% Propolis® cream to fully heal were 5 days, while those with 1.0% Propolis® cream required 6 days. From the t-test for equality of means, where 0.140 > 0.05, we can conclude that the difference is not significant between subjects that were given Propolis® cream at 0.5% concentration compared with subject given with 1.0% concentration of Propolis® cream.The result shows that Propolis at 0.5% concentration provides an average healing period of 5 days while propolis at 1.0% on an average of 6 days for the healing of RAS. Conclusion: Propolis at 0.5% is more effective compared to 1.0% for healing period of Recurrent Aphthous Stomatitis.
The antimicrobial efficacy of siwak (Salvadora persica) extract towards Streptococcus sanguis Bohari, Nurul Iradah; Hardjawinata, Karlina; Sudjarwo, Indrati
Padjadjaran Journal of Dentistry Vol 22, No 2 (2010): July 2010
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol22no2.26848

Abstract

Introduction: Siwak (Salvadora persica) has been used for good oral hygiene maintenance purposes by the Babylonians since 7000 years ago and also by the Greek, Roman, Egyptian, and Arabian. The aim of this study is to assess the antimicrobial efficacy of siwak extract towards Streptococcus sanguis as the oral-plaque-inducer, by determining the Minimum Inhibitory Concentration (MIC) and exposure time, to determine whether siwak extract could be chosen as an alternative ingredient for plaque control. Methods: Type of research is experimental laboratory. The MIC test were conducted based on a serial dilution of 64%, 32%, 16%, 8%, 4%, 2%, 1%, 0.5%, 0.25%, and 0.125% concentration of siwak extract respectively, against 5 samples of Streptococcus sanguis within three repetitions. The exposure time test has been performed within 30 seconds, 1’, 2’, 3’, and 4’ with 0.25%, 0.5%, and 1.0% concentration of siwak extract. Results: The siwak extract can inhibit Streptococcus sanguis at the concentration of 0.25% to 0.125%. There is no antimicrobial effect towards Streptococcus sanguis until 4 minutes of exposure time. Conclusion: Siwak extract had the antimicrobial effect towards Streptococcus sanguis in minimum concentration between 0.25% - 0.125% with the exposure time more than 4 minutes.
Inhibitory concentrations of gambier (Uncaria gambir Roxb.) catechins extract against Streptococcus mutans Inmawaty, Jesieca; Sudjarwo, Indrati; Satari, Mieke Hemiawati
Padjadjaran Journal of Dentistry Vol 24, No 3 (2012): November 2012
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol24no3.26832

Abstract

Introduction: Catechin which extracted from gambir (Uncaria gambir  Roxb) is a major component of polyphenol compounds. The catechins compound acts as an antibacterial. The study was to analyze the inhibitory concentration gambir catechin extract against Streptococcus mutans as the bacteria that play a role in the formation of dental caries. Methods: The study was conducted in a laboratory experiment by testing inhibitory concentration gambir catechin extract, through Kirby Bauer disk diffusion method on plates TYCSB for 1 x 24 hours. Test bacteria Streptococcus mutans isolated from saliva. The used suspension of bacteria was made according to the standard turbidity of Mc Farland 0.5 are each 1 ml suspension containing 1.5 x 108 bacteria. The powder obtained from catechin gambir extract through freezing method. Results: Catechins concentrations of 20% produces the lowest inhibition, with an inhibitory diameter of 0,615 cm. The largest inhibition produces by the concentration of catechins with 80% inhibition at 1,085 cm inhibitory diameter. Conclusion: The higher concentration of catechins, the greater inhibition produces. Conversely, the lower concentration of catechins will be lower inhibition produces. the resulting zone of inhibition will be smaller.
Co-Authors Bohari, Nurul Iradah Han, Foo You Inmawaty, Jesieca Karlina Hardjawinata, Karlina Mieke Hemiawati Satari Riani Setiadhi