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RADIATION THERAPY FOR ENDOMETRIAL STROMAL SARCOMA: A LITERATURE REVIEW Kusumaningrum, Nadia Nita; Dyarma, Kadiota Rasika; Nugroho, Rafiq Sulistyo; Petrarizky, Alfred Julius
International Journal of Radiology and Imaging Vol. 3 No. 02 (2024): International Journal of Radiology and Imaging
Publisher : Department of Radiology, Medical Faculty, University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.ijri.2024.003.02.6

Abstract

Background: Endometrial Stromal Sarcoma (ESS) is a part of uterine sarcoma that can clinically manifest with abnormal vaginal bleeding, postmenopausal bleeding, uterine enlargement or mass, dysmenorrhea, pelvic pressure, or pain. ESS is divided into four main categories: endometrial stromal nodule, low-grade ESS, high-grade ESS, and undifferentiated uterine sarcoma. Management for ESS includes surgery, chemotherapy, radiotherapy, and hormone therapy. We want to review the role of radiation therapy for endometrial stromal sarcoma, from several pieces of literature. Material and Methods: We are conducting a literature review to describe the role of radiation therapy for ESS. Results: Radiotherapy serves as an adjuvant treatment in ESS, potentially improving prognosis and survival rates. While early-stage ESS may not necessitate radiotherapy, it can be considered for ESS cases with metastasis or when surgery is not an option. Conclusion: According to previous studies, radiotherapy for ESS can improve disease-free survival and increase patient survival. On the other hand, there are studies that still require large-scale prospective studies to validate the effectiveness of radiotherapy for ESS. Keywords: Endometrial Stromal Sarcoma, Radiotherapy, Effectiveness
The Correlation Between Cervical Provocation Tests and Compression Severity in EMG Findings of Cervical Root Syndrome Patients Zahra, Farah Shabri Alifia; Kurniawan, Shahdevi Nandar; Petrarizky, Alfred Julius
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.939

Abstract

Background: Medical professionals are often found using cervical provocation tests and Electromyography (EMG) examination to diagnose Cervical Root Syndrome (CRS). Although EMG examinations are unavailable in primary health care facilities due to the lack of equipment, the results of cervical provocation tests are expected to correlate with the findings of the EMG examination. Objective: This study aimed to investigate the correlation between cervical provocation tests (Lhermitte and Spurling) and compression severity of CRS. Methods: 85 medical records that met the inclusion and exclusion criteria were selected using a stratified random sampling method. Subsequently, cervical provocation tests were scaled ordinal, stratified into negative, positive 1, and positive 2, while compression severity was grouped into mild, moderate, and severe. The data obtained was analyzed using SPSS, and correlation analysis was conducted using the Spearman method. Results: The result showed that cervical provocation tests had a very weak negative correlation with the CRS compression severity, and the values obtained were not statistically significant (R = -0.105 and p = 0.341). Conclusion: The results showed that there was no significant correlation between cervical provocation tests and CRS compression severity. Therefore, cervical provocation tests cannot be depended on as a representation of CRS compression severity.
IMPLEMENTATION OF AAPM TG-218 FOR PATIENT SPECIFIC QUALITY ASSURANCE (PSQA) IN THE CASE OF THORACIC TARGET REGION USING IMRT RADIOTHERAPY TECHNIQUE WITH EPID aSi-1200 Listiono, Firza Indrastata; Noor, Johan Andoyo Effendi; Herwiningsih, Sri; Dwiyono, Agustinus Gatot; Martono, Sri; Nugroho, Rafiq Sulistyo; Petrarizky, Alfred Julius
Indonesian Physical Review Vol. 8 No. 3 (2025)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ipr.v8i3.502

Abstract

The implementation of Patient-Specific Quality Assurance (PSQA) is crucial for ensuring the accuracy and safety of Intensity-Modulated Radiation Therapy (IMRT). This study evaluates the application of AAPM TG-218 recommendations in PSQA for thoracic region treatment using the IMRT technique. The study compares two PSQA methods, Perpendicular Composite (PC) and Perpendicular Field-by-Field (PFF), using Electronic Portal Imaging Device (EPID). Measurements were conducted on 10 IMRT patients using a Varian TrueBeam Linac and Eclipse TPS. The Gamma Index (GI) analysis with criteria 3%/3 mm, 3%/2 mm, and 2%/2 mm was used to assess dose distribution accuracy. The results indicate that the average Gamma Passing Rate (GPR) for 3%/2 mm criteria exceeded 95%, which is appropriate with AAPM TG-218 standards. However, stricter criteria (2%/2 mm) did not reach the minimum recommended values. The study suggests that PSQA using EPID with the PFF method under rotational gantry conditions is the most suitable approach for thoracic IMRT treatment verification. The local standardization recommendations from the results of this study can be used as a reference for determining methodological standards in cases of the thoracic region in the IMRT technique to increase efficiency in clinical applications with similar PSQA dosimetry.
INCIDENTAL BONE METASTASIS FINDING FROM CT SIMULATION FOR BREAST CANCER RADIOTHERAPY Nugroho, Rafiq Sulistyo; Amalia, Fini; Bayhaqi Nashir Aslam, Achmad; Petrarizky, Alfred Julius
International Journal of Radiology and Imaging Vol. 3 No. 01 (2024): International Journal of Radiology and Imaging
Publisher : Department of Radiology, Medical Faculty, University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776//ub.ijri.2024.003.01.1

Abstract

Breast cancer has the highest tendency for bone metastasis. This study aimed to evaluate bone metastasis using computed tomography (CT) simulation for breast cancer radiotherapy. We retrospectively reviewed the patient's CT images from September 2022 to February 2023. The median age was 48 (34–80), and almost half of the patients had T3-4 and N2-3 disease. Nine out of 53 patients (17%) had bone metastasis, and 8 had multiple lesions. The vertebral spine was the predominant site of bone metastasis. Due to the high rate of bone spreading, bone evaluation is mandatory during CT simulation for more appropriate treatment. Keywords: Bone metastasis, computed tomography, breast cancer