Garuda - Garba Rujukan Digital

Surface Contamination Of Covid-19: How Long Can The Virus Last? Yusnianingsih, Cuay; Evangelina, Shannon Marcella
Medicinus Vol 8, No 3 (2019): June 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2468

The novel coronavirus, which is now known as COVID-19, has caused a global pandemic. It is known that the main transmission routes of the novel coronavirus are through droplets, close human-to-human contact, and contact with inanimate surfaces contaminated by the virus. Thus, it is important to find out how long SARS-CoV-2 can remain viable on different surfaces. A study by van Doremalen et al. (2020) found that SARS-CoV-2 can remain viable for up to 72 hours on plastic and stainless steel surfaces, 4 hours on copper, and 24 hours on cardboard. Chin et al. (2020) reported that SARS-CoV-2 could persist on wood and cloth for 2 days, and could last for 4 days on glass and banknotes. These findings indicate that viral contamination of object surfaces is an important and dangerous factor in spread of disease, emphasizing the urgent need for prevention strategies against transmission of infection through contact with inanimate surfaces.

The Anti-Viral and Cognitive Enhancement Properties of Edible Bird's Nest: A Narrative Review Yusnianingsih, Cuay
Bali Medical and Wellness Journal Vol. 1 No. 3 (2024): Bali Medical and Wellness Journal
Publisher : PT BMW Journal Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71341/bmwj.v1i3.22

Background: Edible bird's nest has been used as a traditional Chinese medicine since the 7th century. It is rich in protein, carbohydrates, moisture, ash, and fat. Recent research has focused on its potential health benefits, such as anti-viral properties, cognitive enhancement, and roles as an immunomodulator and antioxidant. Objective: This review explores the anti-viral and cognitive enhancement properties of edible bird's nest. Methods: This review followed the PRISMA Scoping Review (PRISMA ScR) guidelines. Relevant studies were systematically identified using PubMed and Google Scholar with keywords such as "edible bird's nest," "anti-viral," "cognitive enhancer," and "Alzheimer's disease." In vitro and in vivo studies published in peer-reviewed journals that focused on the anti-viral and cognitive effects of edible bird's nest were included. Articles were initially screened through titles and abstracts, and relevant studies were reviewed in full to extract key data on study design, methods, and outcomes. Results: Edible bird's nest enhances cell functions by increasing the density and number of lysosomes, reducing Rab5 protein activity, enhancing mucin production, and modulating Rhoa expression, which regulates actin cytoskeleton dynamics. These mechanisms inhibit the attachment, endocytosis, maturation, and release of influenza A virus particles. As a cognitive enhancer, edible bird's nest significantly improves memory and neuroprotective functions by inhibiting neuroinflammatory processes and oxidative stress. Additionally, it may enhance mitochondrial function and increase the number of active mitochondria. Conclusion: Edible bird's nest demonstrates anti-viral and cognitive enhancement effects with no reported side effects in vitro and in vivo. Further research should aim at clinical trials to establish effective and optimal dosages.

Surface Contamination Of Covid-19: How Long Can The Virus Last? Yusnianingsih, Cuay; Evangelina, Shannon Marcella
Medicinus Vol. 8 No. 3 (2019): June 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2468

The novel coronavirus, which is now known as COVID-19, has caused a global pandemic. It is known that the main transmission routes of the novel coronavirus are through droplets, close human-to-human contact, and contact with inanimate surfaces contaminated by the virus. Thus, it is important to find out how long SARS-CoV-2 can remain viable on different surfaces. A study by van Doremalen et al. (2020) found that SARS-CoV-2 can remain viable for up to 72 hours on plastic and stainless steel surfaces, 4 hours on copper, and 24 hours on cardboard. Chin et al. (2020) reported that SARS-CoV-2 could persist on wood and cloth for 2 days, and could last for 4 days on glass and banknotes. These findings indicate that viral contamination of object surfaces is an important and dangerous factor in spread of disease, emphasizing the urgent need for prevention strategies against transmission of infection through contact with inanimate surfaces.

The Role of Omega-3 Fatty Acids in Mitigating Metabolic Risk Factors Associated with Alzheimer's Disease: A Systematic Review and Meta-Analysis Harimawan, Agustinus I Wayan; Yusnianingsih, Cuay; Prabandari, Anak Agung Sagung Mirah
Bali Medical and Wellness Journal Vol. 2 No. 2 (2025): Bali Medical and Wellness Journal
Publisher : PT BMW Journal Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71341/bmwj.v2i2.42

Background: Alzheimer’s disease (AD) is linked to metabolic conditions like obesity and hypertension, which share inflammation and oxidative stress as common factors. Omega-3 fatty acids (EPA and DHA) may have neuroprotective and anti-inflammatory benefits. Objective: This study aims to review the effectiveness of omega-3 supplements in reducing metabolic risk factors and slowing cognitive decline in people with AD. Methods: Following PRISMA guidelines, a comprehensive search was conducted in PubMed, ScienceDirect, and Google Scholar for randomized controlled trials (RCTs) published until July 2025. Eligible studies included older adults (≥65 years) with AD or mild cognitive impairment (MCI) and assessed the impact of omega-3 supplements on cognitive and/or metabolic outcomes. The risk of bias was evaluated using the Cochrane ROB-2 tool. Data were analyzed with Review Manager 5.4 using fixed-effects models for continuous outcomes. Results: Five RCTs with a total of 490 participants were included. Meta-analysis of four trials (326 participants) revealed that omega-3 supplementation significantly improved Mini-Mental State Examination (MMSE) scores compared to placebo (mean difference: 0.21; 95% CI: 0.02–0.41; P = 0.03; I² = 0%). No significant effects were found for ADAS-Cog scores (mean difference: 0.11; 95% CI: –0.40 to 0.62; P = 0.68; I² = 46%) or IADL scores (mean difference: 0.48; 95% CI: –0.17 to 1.13; P = 0.15; I² = 36%). Conclusion: Omega-3 fatty acids may offer modest cognitive benefits in AD, though heterogeneity among studies limits general conclusions. Future well-designed RCTs should consider metabolic profiles and standardized dosing to identify populations most likely to benefit from omega-3 supplementation.

Title

Found 4 Documents
Search

Abstract

Abstract

Abstract

Abstract

Title Search

Found 4 Documents Search

Abstract

Abstract

Abstract

Abstract

Title

Found 4 Documents
Search