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All Journal E-Jurnal Medika Udayana World Nutrition Journal Bali Medical and Wellness Journal
Prabandari, Anak Agung Sagung Mirah
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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HUBUNGAN KARAKTERISTIK PASIEN DENGAN DERAJAT KLINIS ASMA DI RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR Prabandari, Anak Agung Sagung Mirah; Suardamana, Ketut; Paramita Ayu, Nyoman
E-Jurnal Medika Udayana Vol 11 No 9 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i9.P14

Abstract

Asma merupakan penyakit tidak menular dengan kasus terbanyak pada anak-anak. Data mengenai karakteristik pasien asma di Indonesia telah banyak ditemukan, namun data hubungan karakteristik pasien tersebut terhadap derajat klinis asma masih jarang dilaporkan, padahal data ini penting untuk perencanaan penanganan dan pencegahan asma yang prevalensinya terus meningkat. Tujuan penelitian ini yaitu untuk mengetahui hubungan karakteristik pasien dengan derajat klinis asma di RSUP Sanglah Denpasar. Penelitian ini merupakan penelitian analitik cross sectional yang dilakukan di Rumah Sakit Umum Pusat (RSUP) Sanglah Denpasar. Sumber data adalah 81 rekam medis pasien asma periode Januari 2016 – Desember 2016. Variabel bebas adalah usia diagnosis, jenis kelamin, tempat tinggal, kegemukan, atopi, dan merokok, sedangkan variabel tergantung adalah derajat klinis asma meliputi intermiten dan persisten. Data dianalisis dengan menggunakan uji chi square. Hasil penelitian menunjukkan adanya hubungan signifikan antara kegemukan (OR=10,96; 95%CI=2,31-52,03; p=0,03), riwayat atopi (OR=6,66; 95%CI=1,39-31,34; p=0,017), dan onset anak-anak (OR=0,22; 95%CI=0,06-0,87; p= 0,03) dengan derajat klinis asma, sedangkan tidak ada hubungan signifikan antara jenis kelamin, tempat tinggal, dan merokok dengan derajat klinis asma. Kata Kunci: karakteristik pasien, asma, derajat klinis, RSUP Sanglah
Micronutrients intake as risk factor of stunting in toddlers aged 6-24 months in Kintamani District, Bali Prabandari, Anak Agung Sagung Mirah; Sirait, Josephine Claudia; Wijanadi, M.Candra; Harimawan, Agustinus I Wayan
World Nutrition Journal Vol. 8 No. S1 (2024): Selected conference proceedings of the Nutri Symposium 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.S1.0028

Abstract

Reducing stunting is a priority program for the Indonesian government. Kintamani District is one of the areas in Bali Province with a stunting prevalence above the provincial average. Micronutrients play an essential role in growth and development, but their intake in children is often overlooked. This study aimed to investigate micronutrient intake as a risk factor for stunting in toddlers aged 6-24 months in the Kintamani district, Bali.
The Importance of Husband Support in Exclusive Breastfeeding: A Cross-Sectional Study Prabandari, Anak Agung Sagung Mirah; Krishnandita, Maria; Yunanda, Suyasa Adryan; Wijaya, Made Indra
Bali Medical and Wellness Journal Vol. 1 No. 1 (2024): Bali Medical and Wellness Journal
Publisher : PT BMW Journal Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71341/bmwj.v1i1.10

Abstract

Introduction: Despite the significant benefits of breastfeeding, the proportion of exclusive breastfeeding in Indonesia remains low. Husbands, being one of the closest persons to breastfeeding mothers, might be an appropriate target for breastfeeding promotion. This study aims to investigate husband support in exclusive breastfeeding. Methods: A cross-sectional study was conducted in the working area of Dawan II Community Health Center from October to December 2018. Data was collected using questionnaires given to mothers with babies aged 6-24 months who had a husband. Analysis was performed using chi-square test and logistic regression on SPSS version 21. Results: The proportion of exclusive breastfeeding was 55.8%. Chi-square test revealed that husband support has a significant association with exclusive breastfeeding, with a PR of 3.6 (p<0.001; 95%CI= 1.48-8.73). Other associated variables were mother's educational level and parity. Multivariate analysis confirmed the association of husband's support with exclusive breastfeeding (AOR=14.22; p=0.004). Conclusion: Husband support is crucial in exclusive breastfeeding, and husbands should also be targeted for health promotion regarding exclusive breastfeeding.
The Potential of Curcumin as Prevention and Alternative Treatment for Helicobacter Pylori Associated Diseases Prabandari, Anak Agung Sagung Mirah; Sari, Ni Nyoman Shinta Prasista
Bali Medical and Wellness Journal Vol. 1 No. 3 (2024): Bali Medical and Wellness Journal
Publisher : PT BMW Journal Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71341/bmwj.v1i1.13

Abstract

Introduction: Helicobacter pylori (H. pylori) is a pathogenic bacterium found in half of the world's population, causing gastrointestinal problems ranging from gastritis and peptic ulcers to gastric cancer. Current triple therapy treatment for H. pylori faces issues of resistance, side effects, and high cost, necessitating alternative therapies. Studies suggest that curcumin, a compound found in turmeric, may have antibacterial effects against H. pylori. Method: This literature review evaluated the potential of curcumin against H. pylori infection. Relevant articles were systematically searched in PubMed, Scopus, Web of Science, and Google Scholar databases using combinations of keywords including "curcumin," "turmeric," "Helicobacter pylori," "antibacterial," "anti-inflammatory," "antioxidant," and "bioavailability." Results: Curcumin, a polyphenol compound extracted from turmeric, possesses antibacterial, anti-inflammatory, anti-carcinogenic, and antioxidant properties. Turmeric is a natural, inexpensive, and readily available plant in Indonesia. Curcumin prevents H. pylori-associated diseases by inhibiting bacterial adherence to gastric cells and exhibiting bactericidal effects through disruption of bacterial metabolic enzymes and inhibition of ammonia production. Additionally, curcumin treats H. pylori-induced inflammation by suppressing inflammatory pathways such as NF-κB, AP-1, JNK, and MAPK. Conclusion: Curcumin shows potential as both a preventive and therapeutic agent for H. pylori-associated diseases. Further research should focus on improving curcumin's delivery system to enhance its efficacy in clinical applications.
The Role of Omega-3 Fatty Acids in Mitigating Metabolic Risk Factors Associated with Alzheimer's Disease: A Systematic Review and Meta-Analysis Harimawan, Agustinus I Wayan; Yusnianingsih, Cuay; Prabandari, Anak Agung Sagung Mirah
Bali Medical and Wellness Journal Vol. 2 No. 2 (2025): Bali Medical and Wellness Journal
Publisher : PT BMW Journal Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71341/bmwj.v2i2.42

Abstract

Background: Alzheimer’s disease (AD) is linked to metabolic conditions like obesity and hypertension, which share inflammation and oxidative stress as common factors. Omega-3 fatty acids (EPA and DHA) may have neuroprotective and anti-inflammatory benefits. Objective: This study aims to review the effectiveness of omega-3 supplements in reducing metabolic risk factors and slowing cognitive decline in people with AD. Methods: Following PRISMA guidelines, a comprehensive search was conducted in PubMed, ScienceDirect, and Google Scholar for randomized controlled trials (RCTs) published until July 2025. Eligible studies included older adults (≥65 years) with AD or mild cognitive impairment (MCI) and assessed the impact of omega-3 supplements on cognitive and/or metabolic outcomes. The risk of bias was evaluated using the Cochrane ROB-2 tool. Data were analyzed with Review Manager 5.4 using fixed-effects models for continuous outcomes. Results: Five RCTs with a total of 490 participants were included. Meta-analysis of four trials (326 participants) revealed that omega-3 supplementation significantly improved Mini-Mental State Examination (MMSE) scores compared to placebo (mean difference: 0.21; 95% CI: 0.02–0.41; P = 0.03; I² = 0%). No significant effects were found for ADAS-Cog scores (mean difference: 0.11; 95% CI: –0.40 to 0.62; P = 0.68; I² = 46%) or IADL scores (mean difference: 0.48; 95% CI: –0.17 to 1.13; P = 0.15; I² = 36%). Conclusion: Omega-3 fatty acids may offer modest cognitive benefits in AD, though heterogeneity among studies limits general conclusions. Future well-designed RCTs should consider metabolic profiles and standardized dosing to identify populations most likely to benefit from omega-3 supplementation.
Co-Authors Harimawan, Agustinus I Wayan Ketut Suardamana Krishnandita, Maria Nyoman Paramita Ayu Sari, Ni Nyoman Shinta Prasista Sirait, Josephine Claudia Wijanadi, M.Candra Wijaya, Made Indra Yunanda, Suyasa Adryan Yusnianingsih, Cuay