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PENGARUH PEMBERIAN GENISTEIN TERHADAP PENURUNAN KADAR TNF ALPHA PADA ZALIR PERITONEAL MENCIT MODEL ENDOMETRIOSIS Wulandari, Rr. Catur Leny
EMBRIO Vol 10 No 1 (2018): EMBRIO (MEI 2018)
Publisher : Program Studi S1 Kebidanan - Fakultas Sains dan Kesehatan Universitas PGRI Adi Buana Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (404.176 KB) | DOI: 10.36456/embrio.vol10.no1.a1429

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian genistein terhadap penurunan kadar TNF-α studi pada (Mus musculus) model endometriosis. Penelitian dibagi menjadi 8 kelompok, yaitu : kontrol negatif, kontrol positif dengan perlakuan pemberian genistein dosis 50 mg/hari, 100 mg/hari, 200 mg/hari, 300 mg/hari, 400 mg/hari, 500 mg/hari. Pengukuran kadar TNF-α menggunakan ELISA kit. Data hasil pengamatan dianalisis dengan uji Kruskal Wallis dan uji Perbandingan berganda |Ri-Rj| 5%.Menggunakan mencit model endometriosis.Penelitian ini merupakan penelitian eksperimental murni (true experimental) dengan menggunakan rancangan percobaan dengan metode randomized post-test control group design., dilakukan di Laboratorium Fisiologi Reproduksi Embriologi Fakultas Kedokteran Hewan Universitas Airlangga Surabaya dan Laboratorium Fisiologi Fakultas Kedokteran Universitas Brawijaya. Ada pengaruh pemberian genistein terhadap kadar TNF-α dalam cairan peritoneal mencit model endometriosis (p<0,05). Genistein mampu menurunkan kadar TNF-α terendah pada dosis 100 mg/hari (148.25±7.89 pg/ml) bila dibandingkan dengan perlakuan dosis yang lain.
EFEKTIVITASPELVIC ROCKING EXERCISE PADA IBU BERSALIN KALA I TERHADAP KEMAJUAN DAN LAMA PERSALINAN Wulandari, RR. Catur Leny; Wahyuni, Sri
Intan Husada : Jurnal Ilmiah Keperawatan Vol. 7 No. 1 (2019): Vol. 7. No. 1 Januari 2019
Publisher : Politeknik Insan Husada Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52236/ih.v7i1.139

Abstract

Pendahuluan. Proses kemajuan persalinan kala I fase aktif pada primigravida dipengaruhi oleh dilatasiservik dan penurunan kepala janin kedasar panggul. Pelvic rocking merupakan cara untuk mempercepatproses persalinan yaitu dengan menggerakan panggul searah putaran selama kontraksi berlangsung.Mengayunkan dan menggoyangkan panggul kearah depan dan ke belakang, sisi kanan kiri dan melingkarakan terasa lebih relaks dan mempermudah membukanya jalan lahir pada waktu persalinan. Tujuandari penelitian ini adalah mengetahui efektifitas pelvic rockingterhadap lamanya persalinankala Ifase aktif dan lama Kala II. Metode. Penelitian ini merupakan penelitian kuantitatif dengan rancangan quasi experiment, yaitu post testonly design. Penelitian dilakukan di RSUD Ungaran yang telah memberikan intervensi pelvic rockingpadaibu bersalin dengan jumlah responden 28 orang selama bulan September 2018 sampai dengan Desember2018 (14 pada kelompok intervensi dan 14 pada kelompok kontrol). Teknik sampling dengan consecutivesampling. Analisa dengan chi square. Instrumen yang digunakan adalah lembar observasi yang dilakukanoleh Bidan di RSUD Ungaran. Hasil Penelitian.Ada hubungan antara Pelvick Rocking Exercisedengan lama kala I dengan p value 0,008(<0,05) dan ada hubungan antara Pelvick Rocking Exercise dengan lama Kala II dengan p value0,007(<0,05). Ibu bersalin Kala I yang melakukan PRE dapat mempercepat kemajuan dan lama persalinan.Kata Kunci: Lamakala I fase aktif ,lama kala II, pelvic rocking
The Effectiveness of Using the Modern Reminder My Therapy Application on Fe Tablet Consumption Adherence Wulandari, Rr. Catur Leny; Jannah, Muliatul; Ludin, Putri Febriyanti
JURNAL KEBIDANAN Vol 14, No 2 (2024): Oktober 2024
Publisher : Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkb.v14i2.11084

Abstract

Background:Pregnant women have a low level of adherence to Fe tablet consumption, due to the factor of forgetting to take medicine and side effects. One of the efforts to improve adherence is to use a reminder application-based intervention, which can improve adherence in mothers who often forget to take Fe tablets.Objective:This study aimed to determine the effectiveness of using the My Therapy Modern Reminder Application on adherence to Fe Tablet Consumption in the Bangetayu Public Health Center Working Area, Semarang City.Methods:it was quasi-experimental with one group pretest, posttest design. Sampling in this study used a purposive sampling technique with a total sample of 45 respondents and data collection using the MMAS-8 questionnaire. The analysis method used the Wilcoxon test.Results:There was a significant difference between the results of the pre-test and post-test (p = 0.00). Wilxocon test results showed the effectiveness of using my therapy modern reminder application on Fe tablet consumption adherence (p = 0.00).Conclusion:The use of my modern therapy reminder application can improve the adherence of pregnant women to consuming Fe tablets.
Hubungan Tingkat Pengetahuan Kehamilan Di Usia Remaja Dengan Kesehatan Mental di Kabupaten Tegal Wulandari, Rr. Catur Leny; Yunita Setiya Aryani; Arum Meiranny
Journal of Midwifery and Health Science of Sultan Agung Vol. 3 No. 2 (2024): JMHSA
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pregnancy among teenagers has quite high risks for their psychological condition and the maturity of their reproductive organs. One of the problems that can influence the incidence of teenage pregnancy is the level of knowledge of teenagers and their mental health conditions which are not prepared from the start. Lack of knowledge about sexuality will have a negative impact on the mother's mental health. Therefore, the aim of this research is to determine the relationship between knowledge of teenage pregnancy and mental health in Tegal Regency. This research method is quantitative research with a cross sectional approach, sampling using purposive sampling, namely using subjects as many as 73 cases of teenage pregnancy who met the inclusion criteria and were analyzed using univariate analysis and bivariate analysis using chi square analysis. The research results obtained were that there was no significant relationship between knowledge of teenage pregnancy and mental health, p-value 0.856 (α = <0.05). This research can be concluded that there is no significant relationship between the level of knowledge of teenage pregnancy and mental health.
Literature Review Of The Relationship Between Anemia In Pregnant Women And The Incidence Of Low Birth Weight Zahroh, Fatimatul; Wulandari, Rr. Catur Leny
Jurnal Maternitas Kebidanan Vol. 10 No. 1 (2025): Jurnal Maternitas Kebidanan
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jumkep.v10i1.7676

Abstract

Anemia occurs when there are not enough red blood cells to meet the body's physiological needs. Anemia in pregnant women can affect the likelihood of low birth weight babies (LBW). This article aims to find out the relationship between anemia in pregnant women and the incidence of low birth weight. The search method was carried out through online databases, such as Goggle Scholars and Pubmed which were in accordance with the inclusion criteria in 5 national journals and 5 international journals. The results of ten analyzes from five national journals and five international journals from 2019 to 2024 show that there is a link between anemia in pregnant women and the incidence of low birth weight babies (LBW). However, one journal stated that there was no association between anemia in pregnant women and the incidence of low birth weight babies (LBW).
The Effectiveness of Using the Modern Reminder My Therapy Application on Fe Tablet Consumption Adherence Wulandari, Rr. Catur Leny; Jannah, Muliatul; Ludin, Putri Febriyanti
JURNAL KEBIDANAN Vol. 14 No. 2 (2024): Oktober 2024
Publisher : Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkb.v14i2.11084

Abstract

Background:Pregnant women have a low level of adherence to Fe tablet consumption, due to the factor of forgetting to take medicine and side effects. One of the efforts to improve adherence is to use a reminder application-based intervention, which can improve adherence in mothers who often forget to take Fe tablets.Objective:This study aimed to determine the effectiveness of using the My Therapy Modern Reminder Application on adherence to Fe Tablet Consumption in the Bangetayu Public Health Center Working Area, Semarang City.Methods:it was quasi-experimental with one group pretest, posttest design. Sampling in this study used a purposive sampling technique with a total sample of 45 respondents and data collection using the MMAS-8 questionnaire. The analysis method used the Wilcoxon test.Results:There was a significant difference between the results of the pre-test and post-test (p = 0.00). Wilxocon test results showed the effectiveness of using my therapy modern reminder application on Fe tablet consumption adherence (p = 0.00).Conclusion:The use of my modern therapy reminder application can improve the adherence of pregnant women to consuming Fe tablets.
Pengaruh Edukasi Kesehatan Berbasis Video Terhadap Pengetahuan Dan Sikap Pencegahan Anemia Pada Remaja Putri Di SMK Cut Nya’ Dien Semarang Nikmah, Ndakirotun; Wulandari, Rr. Catur Leny; Arisanti, Atika Zahria
Innovative: Journal Of Social Science Research Vol. 5 No. 3 (2025): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v5i3.19564

Abstract

Anemia merupakan masalah kesehatan yang sering dialami remaja putri akibat masa pertumbuhan, menstruasi, dan pola makan tidak seimbang. Kurangnya pengetahuan dan sikap pencegahan menjadi faktor tingginya kasus anemia. Penelitian ini bertujuan untuk mengetahui pengaruh edukasi kesehatan berbasis video terhadap peningkatan pengetahuan dan sikap pencegahan anemia pada remaja putri di SMK Cut Nya’ Dien Semarang. Metode yang digunakan adalah pre-eksperimen dengan desain one group pretest-posttest pada 44 responden yang dipilih secara total sampling. Intervensi berupa video edukasi berdurasi 3 menit 22 detik. Hasil menunjukkan peningkatan skor pengetahuan dari 16,95 menjadi 18,15 dan skor sikap dari 7,77 menjadi 12,95. Uji Wilcoxon menunjukkan perbedaan signifikan (p = 0,003 untuk pengetahuan dan p = 0,000 untuk sikap). Edukasi berbasis video efektif meningkatkan pengetahuan dan sikap remaja putri dalam mencegah anemia.