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ANTI-INFLAMMATION ACTIVITY OF AGERATUM CONYZOIDES LEAF ETHANOL EXTRACT ON RATTUS NORVEGICUS Saputri, Maylani Permata; Utami, Riani; Fadila, Jasmine; Handayani, Santi Nur
Walisongo Journal of Chemistry Vol 3, No 1 (2020): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (856.735 KB) | DOI: 10.21580/wjc.v3i1.6136

Abstract

Bandotan  (Ageratum conyzoides L) merupakan tanaman yang mengandung senyawa metabolit sekunder berupa flavonoid dan alkaloid yang diduga mempunyai efek anti-inflamasi.  Tujuan penelitian adalah mengetahui aktivitas anti-inflamasi ekstrak etanol daun A. conyzoides pada tikus yang diinduksi karagenan. Tahapan penelitian adalah maserasi daun A. conyzoides dalam pelarut etanol, uji fitokimia, dan uji aktivitas anti-inflamasi. Uji aktivitas anti-inflamasi dilakukan terhadap 25 tikus putih (Rattus norvegicus L.) jantan yang terbagi menjadi lima kelompok perlakuan yaitu kontrol (-) larutan CMC 0,5%, kontrol (+) natrium diklofenak, dan pemberian ekstrak dengan dosis 30, 200 dan 448 mg/kgBB. Parameter yang diamati yaitu volume kaki tikus setelah diinduksi 0,1 mL karagenan 1% selama 300 menit diukur dengan pletismometer. Hasil uji anti-inflamasi menunjukkan bahwa ekstrak etanol daun A. conyzoides dengan dosis 30, 200 dan 448 mg/kgBB memiliki aktivitas anti-inflamasi dengan persen daya anti-inflamasi masing-masing sebesar 10,43; 21,67; dan 30,34 %. Dosis 448 mg/kgBB menunjukkan tidak ada perbedaan signifikan dengan kontrol (+) pada uji ANOVA. Hasil penelitian menunjukkan ekstrak etanol daun A. conyzoides memiliki aktivitas anti-inflamasi.
On the Interaction between Trichogramma chilonis and Jatiroto Flies with Stem Borer Pests in Sugarcane Plantation Fauzi, Rifky; Mufidah, Zunanik; Maretta, Gres; Edriani, Tiara Shofi; Rizka, Nela; Mukhaiyar, Utriweni; Utami, Riani; Haryani, Sri; Saefudin, Saefudin; Styaningrum, Amalia; Soewono, Edy
Journal of Mathematical and Fundamental Sciences Vol. 56 No. 3 (2024)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2024.56.3.3

Abstract

Pests in sugarcane plantations are a major cause of damage, which could lead to severe damage to the crop, reduction of sugar quality, and significant economic loss. One of the major pests known in sugarcane plantations is stem borer (Chilo sacchriphagus), which attacks the canes. Two primary parasitoids, Trichogramma chilonis, which predates the stem borer eggs, and the Jatiroto fly (Diatraeophaga striatalis), which predates the stem borer larvae, are discussed here. This paper presents a time-dependent ten-dimensional dynamical mathematical model consisting of four-stage stem borer compartments, three-stage Trichogramma compartments, and three-stage Jatiroto compartments. Simulations are presented to describe the phenomenon of Trichogramma predation, Jatiroto predation, and simultaneous predation of both predators. It is shown that the release rate of each predator and a combined release of two predators can significantly reduce the infestation levels to a tolerable level for sugarcane production. The oscillatory dynamics of the stem borers and the Jatiroto flies affected the release timing strategy based on the level of infestation in the field. The results are expected to help us better understand the predator-prey phenomenon in the field and improve the forecasting of infestations in the field.