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All Journal Jurnal Pendidikan Matematika dan IPA Al Jahiz: Journal of Biology Education Research Filogeni: Jurnal Mahasiswa Biologi
Sijid, St Aisyah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Physics

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PENGARUH PEMBERIAN TUAK TERHADAP GAMBARAN HISTOPATOLOGI HATI MENCIT (Mus musculus) ICR JANTAN Sijid, St Aisyah; Muthiadin, Cut; Zulkarnain, Zulkarnain; Hidayat, Ar. Syarif
Jurnal Pendidikan Matematika dan IPA Vol 11, No 2 (2020): Juli 2020
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1146.746 KB) | DOI: 10.26418/jpmipa.v11i2.36623

Abstract

Liver damage or liver disease is caused by many factors, one of which is by consuming drinks that contain alcohol. Tuak is one of the drinks that contain alcohol. This study aims to determine the effect of palm wine administration on the histopathological picture of male ICR mice (Mus musculus) liver. This study used 20 mice consisting of 4 treatments namely P0 = 0 mL / day / head; P1 = 0.1 mL / day / head; P2 = 0.2 mL / day / head and P3 = 0.3 mL / day / head. The parameters observed were body weight of mice, liver weight and liver histopathology of mice. The results showed that administration of palm wine to male ICR mice at different doses gave an influence on the histopathological picture of male ICR mice (Mus musculus).AbstrakKerusakan hati atau penyakit liver disebabkan oleh banyak faktor, salah satunya adalah dengan mengkonsumsi minuman yang mengandung alkohol. Tuak merupakan salah satu minuman yang mengandung alkohol. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian tuak terhadap gambaran histopatologi hati mencit (Mus musculus) ICR jantan. Penelitian ini menggunakan 20 ekor mencit yang terdiri dari 4 perlakuan yaitu P0 = 0 mL/hari/ekor; P1 = 0,1 mL/hari/ekor; P2 = 0,2 mL/hari/ekor dan P3 = 0,3 mL/hari/ekor. Parameter yang diamati adalah berat badan mencit, berat hati dan histopatologi hati mencit. Hasil penelitian menunjukkan bahwa pemberian tuak pada mencit ICR jantan dengan dosis yang berbeda memberikan pengaruh terhadap gambaran histopatologi hati mencit (Mus musculus) ICR jantan.Kata Kunci: Hati, Histopatologi, Mencit, Tuak
Immunomodulatory Effects of Synbiotic Lactic Acid Bacteria from Dangke and Inulin from Dahlia Tubers Febriani, Ayu; Hafsan, Hafsan; Sijid, St Aisyah; Nur, Fatmawati; Muthiadin, Cut; Khudaer, Faten
Al Jahiz Vol 6 No 2 (2025): Al-Jahiz: Journal of Biology Education Research, July-December 2025 (In Progress)
Publisher : Fakultas Tarbiyah dan Ilmu Keguruan UIN Jurai Siwo, Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32332/al-jahiz.v6i2.10393

Abstract

Synbiotics, the synergistic combination of probiotics and prebiotics, have attracted growing scientific interest due to their potential to modulate immune responses. However, the immunomodulatory effects of synbiotics derived from traditional foods remain underexplored. This study aimed to evaluate the immune-enhancing potential of synbiotics formulated from Lactobacillus fermentum isolated from Dangke (a traditional South Sulawesi cheese) and inulin extracted from Dahlia tubers. The novelty of this work lies in the utilization of culturally unique, locally sourced microbial and prebiotic components that have not previously been tested for immunological impact. A total of 28 mice were randomly divided into four groups: one negative control group (P0) and three treatment groups (P1, P2, P3) receiving different doses of synbiotics over a 20-day treatment period. Parameters observed included changes in body weight, macrophage phagocytosis activity, and organ indices (liver and spleen). Results showed that mice in P1 and P2 groups exhibited significant increases in body weight (P1: +12.5%, P2: +15.3%, p < 0.05) compared to the control. Moreover, macrophage phagocytic activity was markedly improved in the treatment groups (p < 0.01). Liver and spleen indices were also significantly elevated (p < 0.05), indicating enhanced organ function. These findings suggest that synbiotics containing L. fermentum and Dahlia inulin have promising immunomodulatory effects, highlighting their potential for development as novel functional food ingredients with health-promoting benefits.
Gambaran hasil pemeriksaan mikroskopik basil tahan asam pada penderita tuberkulosis paru di BBKPM Makassar Febriani, Ayu; Sijid, St Aisyah; Hidayat, Kusnadi S; Muthiadin, Cut; Zulkarnain, Zulkarnain
Filogeni: Jurnal Mahasiswa Biologi Vol 2 No 1 (2022): Januari-April
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.855 KB) | DOI: 10.24252/filogeni.v2i1.28631

Abstract

Tuberkulosis adalah penyakit infeksius yang diakibatkan oleh infeksi kuman Mycobacterium tuberculosis yakni bakteri yang berasal dari golongan Basil Tahan Asam (BTA) yang pada kebanyakan kasus ditemukan menyerang organ paru-paru. Penegakan diagnosis tuberkulosis salah satunya dilakukan dengan uji mikroskopik BTA. Pada penelitian ini dilakukan pengujian sampel dahak dari 119 pasien Balai Besar Kesehatan Paru Makassar dengan metode pewarnaan mikroskopik Zheil neelsen, selanjutnya data yang diperoleh dikelompokkan berdasarkan hasil uji, usia serta gender dari sampel. Berdasarkan riset yang telah dilaksanakan diketahui bahwa pemeriksaan BTA dengan hasil positif pada pasien terdiagnosis menderita TB paru yang dikelompokkan berdasarkan usia berasal dari remaja 11-19 (17%) dan dewasa 20-60 Tahun (83%). Selain itu, pengelompokan berdasarkan gender menunjukkan bahwa hasil pemeriksaan positif paling banyak ditemukan pada laki-laki (61%) sedangakan pada perempuan hanya sekitar 39%.
Co-Authors Ar. Syarif Hidayat Cut Muthiadin Fatmawati Nur Febriani, Ayu Hafsan, Hafsan Hidayat, Kusnadi S Khudaer, Faten Zulkarnain Zulkarnain