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All Journal bionature Biology Teaching and Learning
A. Mu’nisa, A. Mu’nisa
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Analisis Penurunan Kadar Glukosa Darah Mencit (Mus musculus) Jantan yang Diberi Ekstrak Metanol Daun Cemba (Acacia pennata) Asal Enrekang Diinduksi Aloksan Maulana, Aji; Suryani, Irma; A. Mu’nisa, A. Mu’nisa
bionature Vol 18, No 1 (2017): april 2017
Publisher : Fakultas MIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (587.963 KB) | DOI: 10.35580/bionature.v18i1.5589

Abstract

Abstract. The Plants Cemba (Acacia pennata) included in family Leguminoceae, which is typical plant in Enrekang, South Sulawesi. The purpose of this research is to determine the effect of methanol extract of cemba leaves to decrease blood glucose levels in mices male ICR strain induced by alloxan. The leaves were extracted using 96% methanol by maceration method. This study is a randomized complete design (RAL), which contains of 5 treatments and 5 replicates. The extract was dissolved using Carboxy Methyl Cellulose (CMC) 0.5% and given orally in mices that had been previously injected by alloxan 120 mg/kg intraperitoneally. The awarding of the extract given different doses i.e., 125, 250 and 500 mg/kg. The data were Analyzed using Analysis of Variance (ANOVA) using SPSS 2.0 Program and continued by Duncan test (α 0:05), as drugs control using glibenclamide 5 mg / kg whereas the normal control using CMC 0.5%. The results showed that 250 mg/kg dose of the extract had a most effective to decrease blood glucose levels during 14 days of given cemba leaves extract. These results were significantly different with negatif control (105.6 mg/dl) and positif control (105.80 mg/dl), as well as groups of mice that were given the cemba leaves extract 150 and 500 mg/kg. Extract of cemba leaves shows the effect of the decrease blood glucose levels in mices male.Keywords: cemba leaves extract, family Leguminoceae, Enrekang.
Pengaruh Pemberian Tepung Tempe terhadap Kadar Kolesterol Total Darah Mencit (Mus musculus) Hiperkolesterol Rumtal, Heryl; Ngitung, Rosdiana; A. Mu’nisa, A. Mu’nisa
bionature Vol 20, No 2 (2019): Oktober
Publisher : Fakultas MIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.141 KB) | DOI: 10.35580/bionature.v20i2.11281

Abstract

Abstract. This research is experimental which aims to determine the effect of giving Tempe Flour to total blood cholesterol concentration of hypercholesterol mice (Mus musculus). The independent variable of this research Tempe Flour while the dependent variable is the total blood cholesterol concentration of mice (Mus musculus). The subject of this research is 25 male ICR strain (Imprinting Control Region) mice with 3 months age divided 5 treatment groups which are normal group, hypercholesterol group, giving of tempe flour at dose of 10 g / day / BB (P1), 20 g / days / BB (P2) and 25 g / day / BB (P3). Tempe flour is given after the giving of cholesterol feed. All mices blood cholesterol concentration were check after the time of treatment. The result is analyz by using ANOVA with Ducan test. The result of this research show that the giving of Tempe Flour affected the decrease of blood cholesterol concentration of mice (Mus musculus) in dose of 10 g/day/BB,20 g/day/BB and 25 g/day/BB. Dose of 25 g/day/BB showed an effective dose for lowering cholesterol in the research.   Keywords: tempe flour, cholesterol, hypercholesterol, mencit (Mus musculus)
Co-Authors Abd Muis Irma Suryani Maulana, Aji Pebrianto, Ahsanul Qadri Rosdiana Ngitung Rumtal, Heryl