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The Effect of Systemic Doxycycline and Mechanical Therapy on GCF β-Glucuronidase Leves in Chronic Periodontitis Patients Zia, Afaf; Gupta, Narendra; Bey, Afshan; Khan, Asad U; Khan, Saif; Andarabi, Syed Mukhtar Un Nisar; Khan, Rosina; Adil, Mohd
Journal of Dentistry Indonesia Vol. 24, No. 2
Publisher : UI Scholars Hub

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Abstract

The goal of periodontal therapy includes management of bacterial pathogens to control the destruction of the periodontal tissue. A number of different nonsurgical and surgical therapies have been used in achieving this goal. Objective: To evaluate the effectiveness of doxycycline compared with nonsurgical therapy alone or in combination with nonsurgical therapy on gingival crevicular fluid β-Glucuronidase levels (ßG) and clinical parameters over a 20-week period in patients with chronic periodontitis. Methods: An interventional study comprising 60 patients with chronic periodontitis. They were divided into three groups of different treatment approach. The plaque index, gingival index, probing depth, and clinical attachment levels were recorded, and gingival crevicular fluid (GCF) samples were collected at 2, 6, 10, and 20 weeks, after treatment. Results: The levels of GCF βG and clinical parameters were higher when the treatment was initiated, and the levels decreased after treatment. No significant difference was found in the βG level when nonsurgical therapy and doxycycline were used alone. In comparison, when doxycyline and nonsurgical therapy were combined, the level of βG decreased significantly. Conclusion: The present study indicated the usefulness of doxycycline as an adjunct to nonsurgical periodontal therapy in lowering GFC βG levels and clinical parameters.
Unveiling the Social Media Magic How TAM, TPB, and Trust Shape Behavior Intentions in the Tourism Sector Khan, Safdar; Adil, Mohd; Rehman, Asad
Journal of Tourism Sustainability Vol. 5 No. 2 (2025): Volume 5 Number 2 (2025)
Publisher : Politeknik Negeri Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35313/jtospolban.v5i2.150

Abstract

Currently, social media plays a pivotal role in the tourism industry, shaping travelers' intentions. In this research, a comprehensive context that combines the TAM proposed by Davis (1989), TPB introduced by Ajzen (1991), and trust is utilized to investigate Social Media Impact on Behavior Intention in the Tourism Sector. In this research, a convenience sampling approach was employed. The data was gathered using an online questionnaire shared via social network pages between October 10, 2023, to November 20, 2023. Hypothesis testing was carried out using the PLS-SEM method, utilizing SmartPLS 3.0 as the statistical analysis software. The study's results showcase the success of merging the theory of planned behavior, technology acceptance model, and trust into a sturdy framework. This model effectively reveals social media impacts behavioral intentions in the tourism industry. Importantly, all hypotheses were confirmed, underscoring the framework's importance in understanding consumer behavior regarding social media and its impact on travel choices. This research delves into how social media affects travel destination choices for Indian consumers. It provides valuable insights into the behavioral intentions of key players in the travel industry, including online tourism businesses, tour managers, and organizers. This study is limited to the Indian context. It offers a distinct contribution by conducting a thorough analysis of the existing research panorama concerning Unveiling the social media Magic: How TAM, TPB, and Trust Shape Behavior Intentions in the Tourism Sector.