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All Journal Journal of Dentistry Indonesia Journal of Case Reports in Dental Medicine
Afaf Zia, Afaf
Department of Periodontology, Dr ZA Dental College, Aligarh Muslim University, Aligarh 202001
Dentistry Health Professions

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The Effect of Systemic Doxycycline and Mechanical Therapy on GCF β-Glucuronidase Leves in Chronic Periodontitis Patients Zia, Afaf; Gupta, Narendra; Bey, Afshan; Khan, Asad U; Khan, Saif; Andarabi, Syed Mukhtar Un Nisar; Khan, Rosina; Adil, Mohd
Journal of Dentistry Indonesia Vol. 24, No. 2
Publisher : UI Scholars Hub

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Abstract

The goal of periodontal therapy includes management of bacterial pathogens to control the destruction of the periodontal tissue. A number of different nonsurgical and surgical therapies have been used in achieving this goal. Objective: To evaluate the effectiveness of doxycycline compared with nonsurgical therapy alone or in combination with nonsurgical therapy on gingival crevicular fluid β-Glucuronidase levels (ßG) and clinical parameters over a 20-week period in patients with chronic periodontitis. Methods: An interventional study comprising 60 patients with chronic periodontitis. They were divided into three groups of different treatment approach. The plaque index, gingival index, probing depth, and clinical attachment levels were recorded, and gingival crevicular fluid (GCF) samples were collected at 2, 6, 10, and 20 weeks, after treatment. Results: The levels of GCF βG and clinical parameters were higher when the treatment was initiated, and the levels decreased after treatment. No significant difference was found in the βG level when nonsurgical therapy and doxycycline were used alone. In comparison, when doxycyline and nonsurgical therapy were combined, the level of βG decreased significantly. Conclusion: The present study indicated the usefulness of doxycycline as an adjunct to nonsurgical periodontal therapy in lowering GFC βG levels and clinical parameters.
Effect of the Extent of Apical Enlargement on the Degree of Debridement of the Apical Third in Curved Root Canals Andrabi, Syed Mukhtar-Un-Nisar; Kumar, Ashok; Tewari, Rajendra Kumar; Mishra, Surendra Kumar; Iftekhar, Huma; Zia, Afaf
Journal of Dentistry Indonesia Vol. 25, No. 3
Publisher : UI Scholars Hub

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Objectives: The present study aimed to evaluate the influence of various apical instrumentation sizes and tapers on the degree of debridement of the apical third of curved root canals. Methods: We used 60 extracted human mandibular first molars with mesial root curvatures of 20° to 30°. In all teeth, access cavity preparation was performed, followed by coronal flaring with Gates Glidden drills #1–4 (Dentsply Maillefer). Specimen teeth were subsequently randomly divided into five groups (n = 12). Each group was enlarged to a particular apical size and taper as follows: no apical preparation done (group I, Control group); 25/.04 and 25/.06 (Group II); 30/.04 and 30/.06 (group III); 35/.04 (group IV); 40/.04 (group V). Specimens were rinsed with 17% EDTA and 3% NaOCl solutions. We used a scanning electron microscope to evaluate specimens’ degree of debridement. Retrieved data were analyzed using Kruskal–Wallis and Mann–Whitney U-tests (p < 0.05). Results: Acceptable debridement was observed in groups III, IV, and V. Additionally, debridement was significantly better in Groups IV and V than in group II. Conclusion: Apical preparation with <30/.04 size results in an unacceptable degree of debridement of the apical third.
Endodontic Periodontic Lesions and Host Modulation – Case Series Zia, Afaf; Bey, Afshan; Andrabi, Syed MUN; Khan, Saif; Khan, Masood
Journal of Dentistry Indonesia Vol. 22, No. 1
Publisher : UI Scholars Hub

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Host modulation, includes inhibition of matrix metalloproteinases, blocking production of proinflammatory cytokines and inhibition of osteoclastic activity, has therapeutic value as adjunctive therapy in treating chronic periodontitis. This case series presented three patients with chief complaint of teeth mobility where endo perio involvement was diagnosed. The endo perio combined lesions generally shows the communication between pulp and periodontal tissues with the same origin of dental infection. Diagnosis in such cases is difficult and generally raising problem in the management. All of the cases were managed by non surgical endodontic therapy combined with host modulation. All local factors causing the lesion were removed. Clinical outcome after six and nine months were quite satisfactory. Combined endo perio cases are challenging to the dentists and involve multidisciplinary involvement. To manage such cases, dentists have to rely on the unconventional techniques.
Management of Ankyloglossia in a Non-Syndromic Patient Using a Super Pulsed Laser: A Life-Changing Treatment- A Case Report Jawed, Urfi; Zia, Afaf; Kumawat, Ramniwas; Bey, Afshan; Mahmood, Maahin
Journal of Dentistry Indonesia Vol. 30, No. 3
Publisher : UI Scholars Hub

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Objective: Ankyloglossia affects a person’s overall well-being and life, from malnutrition due to poor feeding and mechanical problems to psychological stress and low self-esteem, thus affecting social life. This case reports the use of non-scalpel techniques, such as a super pulsed laser, to manage ankyloglossia in a non-syndromic patient suffering from speech incompetence and restricted tongue mobility and highlights its advantages over other conventional techniques. Case Report: A 17-year-old male patient presented with a complaint of restricted tongue mobility, due to which he could not pronounce certain words clearly. As the patient was apprehensive about the use of a scalpel, it was decided to manage ankyloglossia using a diode laser against the conventional scalpel technique. Thus, the laser-assisted lingual frenectomy using GaAs super pulsed laser was used to excise the lingual frenulum. Conclusion: This case report suggests that ankyloglossia can be successfully treated by using laser-assisted surgery and gives superior results specifically in terms of lesser pain and bleeding.
Sinus augmentation and dental implant placement after breast cancer therapy- A case report Mahmood, Maahin; Zia, Afaf; Andrabi, S. Mukhtar UN.; Fatma, Shazra; Ahmad, Mohammad; Jawed, Urfi
Journal of Case Reports in Dental Medicine Vol 7, No 2 (2025)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v7i2.240

Abstract

IntroductionThis case report aims to provide implant-supported rehabilitation in a patient treated for breast cancer using sinus augmentation.MethodsA 57-year-old female patient previously treated for stage 2 breast-cancer with breast-conserving surgery, chemotherapy and radiotherapy presented with missing teeth in her upper right buccal segment and wanted its rehabilitation. Sinus augmentation with hydroxyapatite and ? tricalcium phosphate graft was performed to gain lost bone volume in the region using piezoelectric surgical unit. Final restoration was done using an implant-supported prosthesis.ResultsAfter sinus augmentation, implants were placed and successful osseointegration was observed with uneventful healing. The patient was satisfied with the final outcome of the treatment as proper oral form and function was achieved.ConclusionThis case report suggests that sinus augmentation using a piezoelectric unit followed by implant-supported prosthetic rehabilitation can provide successful outcomes if done cautiously in medically compromised patients.
Co-Authors Adil, Mohd Afshan Bey, Afshan Ahmad, Mohammad Andarabi, Syed Mukhtar Un Nisar Andrabi, S. Mukhtar UN. Andrabi, Syed Mukhtar-Un-Nisar Andrabi, Syed MUN Fatma, Shazra Gupta, Narendra Iftekhar, Huma Jawed, Urfi Khan, Asad U Khan, Rosina Kumar, Ashok Kumawat, Ramniwas Mahmood, Maahin Masood Khan, Masood Mishra, Surendra Kumar Saif Khan, Saif Tewari, Rajendra Kumar