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All Journal Trends in Infection and Global Health
Yusuf, Hanifa
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Phytochemical screening and gel stability test of ethanol extract of Chromolaena odorata L. from Indonesia Handayani, Putri; Yusuf, Hanifa; Gholib, Gholib
Trends in Infection and Global Health Vol 4, No 1 (2024): June 2024
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v4i1.39971

Abstract

Chromolaena odorata L. is a widely used traditional herbal medicine known for its medicinal usage throughout the world. It has been used by the community for its anti-cancer, anti-bacterial, anti-inflammatory, antipyretic, anti-diabetic, and anti-diarrheal, and it also plays a role in hemostasis and wound healing. This study aims to analyze the chemical compounds of C. odorata leaves from Indonesia and to determine the gel stability of its ethanol extract. In this study, C. odorata leaves were collected from Lamkawe Village, Darul Imarah District, Aceh Besar Regency, Aceh, Indonesia. The extraction process was conducted using the maceration method. The active chemical compounds of the ethanol extract of C. odorata leaves were analyzed through phytochemical screening and gas chromatography-mass spectrometry (GC-MS) analysis. The results of the phytochemical screening indicated it contained terpenoids, saponins, flavonoids and phenolics. The most abundant secondary compounds identified were glycidyl palmitate (17.02%), n-9-octadecenoic acid (Z) (15.68%), hexadecanoic acid and l-(+)-ascorbic acid 2,6-dihexadecanoate (12.19%) and 16-hentriacontanone. The 7.5% ethanol extract of C. odorata leaves showed good stability.
Co-Authors Gholib Gholib, Gholib Putri Handayani