Trends in Infection and Global Health
Vol 4, No 1 (2024): June 2024

Phytochemical screening and gel stability test of ethanol extract of Chromolaena odorata L. from Indonesia

Handayani, Putri (Unknown)
Yusuf, Hanifa (Unknown)
Gholib, Gholib (Unknown)



Article Info

Publish Date
31 Jul 2024

Abstract

Chromolaena odorata L. is a widely used traditional herbal medicine known for its medicinal usage throughout the world. It has been used by the community for its anti-cancer, anti-bacterial, anti-inflammatory, antipyretic, anti-diabetic, and anti-diarrheal, and it also plays a role in hemostasis and wound healing. This study aims to analyze the chemical compounds of C. odorata leaves from Indonesia and to determine the gel stability of its ethanol extract. In this study, C. odorata leaves were collected from Lamkawe Village, Darul Imarah District, Aceh Besar Regency, Aceh, Indonesia. The extraction process was conducted using the maceration method. The active chemical compounds of the ethanol extract of C. odorata leaves were analyzed through phytochemical screening and gas chromatography-mass spectrometry (GC-MS) analysis. The results of the phytochemical screening indicated it contained terpenoids, saponins, flavonoids and phenolics. The most abundant secondary compounds identified were glycidyl palmitate (17.02%), n-9-octadecenoic acid (Z) (15.68%), hexadecanoic acid and l-(+)-ascorbic acid 2,6-dihexadecanoate (12.19%) and 16-hentriacontanone. The 7.5% ethanol extract of C. odorata leaves showed good stability.

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Journal Info

Abbrev

TIGH

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

TIGH publishes primary research papers, review articles, short communications and letters on the following topics: Tropical diseases Microbiology Epidemiology Public health Population health One Health Immunology Chronic diseases Surgical disease and surgical care Chemotherapy and pharmacology ...