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All Journal Majalah Kedokteran Bandung Majalah Patologi Indonesia
Mardianty, Friska
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Health Professions Medicine & Pharmacology Public Health

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Clinicopathological Characteristics of Ocular Surface Squamous Neoplasia in National Eye Center, Cicendo Eye Hospital Bandung from 2019 to 2022 Nia Nuraeni; Aminah, Hermin; Agustina, Hasrayati; Mardianty, Friska
Majalah Patologi Indonesia Vol. 34 No. 2, Mei 2025
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v34i3.649

Abstract

Introduction Ocular surface squamous neoplasm (OSSN) comprises a broad spectrum of dysplastic alterations of the squamous epithelium of the conjunctiva, ranging from conjunctival squamous intraepithelial neoplasm (CSIN) to squamous cell carcinoma (SCC). The aim of this study was to describe the clinicopathological characteristics of OSSN at National Eye Center, Cicendo Eye Hospital Bandung from January 2019 to December 2022. Methods We collected OSSN data from 2019 to 2022. The collected data were the patient's age, gender, education, occupation, laterality, clinical features, recurrence, and classification of tumor according to the 2022 WHO classification. Results: A total of 128 cases were collected. The most common tumor identified was SCC (48.4%), followed by CSIN with severe dysplasia (25%), moderate dysplasia, and mild dysplasia (14.8% and 11.7%, respectively). The average patient’s age was 53.1 years (M = 53.1, SD =16.9), predominantly males (68%), education completed elementary school (52.3%), and more patients worked outdoor (59.4%). The most common affected site was the left eye (53.9%), and the tumor located in the nasal region (78.1%) with clinical features is papilliform (64.1%). Conclusion OSSN was predominant in elderly male patients. The majority of cases were seen in the left eye, primarily in the nasal area. The majority of patients had completed elementary school and worked outdoors. Additionally, the clinical symptoms showed that most patients had papilliform. In patients with OSSN, SCC was the most common anatomical pathology discovered. Moreover, recurrence was higher in SCC cases.
Rare Eccrine Porocarcinoma of The Eyelid in A Non-Caucasian Patient Boesoirie, Shanti F.; Mardianty, Friska; Wahyu, Tri; Dewi, Niluh Putu Ayu; Nursalamah, Mia; Dahlan, Mohamad Rinaldi; Kartiwa, Raden Angga
Majalah Kedokteran Bandung Vol 57, No 4 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4193

Abstract

Eccrine porocarcinoma of the eyelid is a rare and locally aggressive tumor with a significant risk of metastasis and recurrence after surgical excision. There are only eight cases of eyelid porocarcinoma reported in the literature, most involve Caucasian patients. A 58-year-old non-Caucasian male had a recurrent mass of the left upper eyelid for a year. He underwent two prior mass removal procedures in the same location of the upper eyelid. At the time of this study, the patient underwent full-thickness excision, and a lateral canthal defect with superior palpebral involvement was sacrificed. The periosteal flap from the lateral orbital rim was attached to the edge of the intact tarsal plate of the upper eyelid as a part of the defect reconstruction. Good outcomes in terms of tumor recurrences, cosmesis, and upper eyelid functionality were observed one month following surgery. According to the histopathology, the tumor was identified as eccrine porocarcinoma, and the patient was recommended for chemotherapy. The 4-month follow-up showed no recurrence or metastasis. Eccrine porocarcinoma is a rare condition that should be taken into account when making a differential diagnosis for patient with malignant eyelid tumors. Wide excision is still a treatment of choice. 
Co-Authors Aminah, Hermin Boesoirie, Shanti F. Dahlan, Mohamad Rinaldi Dewi, Niluh Putu Ayu Hasrayati Agustina Kartiwa, Raden Angga Nia Nuraeni Nursalamah, Mia Tri Wahyu