Fadlilaturrahmah
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Sunscreen Activity and Total Phenolic Content of Jengkol Leaves (Pithecellobium lobatum Benth.) Ethanolic Extract Normaidah; Fitriana, Mia; Fadlilaturrahmah; Kurniasari, Winda Tri; Izma, Hayatun; Ratnapuri, Prima Happy
Pharmacon: Jurnal Farmasi Indonesia Vol. 21 No. 1 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i1.5662

Abstract

Exposure to UV rays can cause several skin problems, such as redness, sunburn, erythema, and ageing. The dangerous effects of UV radiation require more protection of the skin, such as sunscreen. Jengkol leaves (Pithecellobium lobatum Benth.) are a plant that contains phenolic compounds that can absorb UV radiation, so they can act as sunscreens. This study aimed to determine the activity of sunscreen using in vitro methods in the ethanol extract of P. lobatum leaves based on the sun protection factor (SPF),% transmission of erythema (% Te), % transmission of pigmentation (% Tp) and its total phenolic content by UV-vis spectrophotometry. The best sunscreen activity of the ethanolic extract of P. lobatum leaves was at a concentration of 400 ppm with an SPF value of 28.29 ± 0.034 (ultra), % Te and % Tp were included in the sunblock category. The total phenolic content of the ethanolic extract of the leaves of P. lobatum was 394.45 ± 6.40 mg of gallic acid equivalent per gram extract (mg GAE/g extract). The ethanolic extract of the Pithecellobium lobatum leaves has great potential as a sunscreen product.
POTENSI ANTI-INFLAMASI DAN KADAR FLAVONOID TOTAL EKSTRAK ETIL ASETAT DAUN KOKANG (Lepisanthes amoena) YANG DIEVALUASI DENGAN METODE INHIBISI DENATURASI PROTEIN Fadlilaturrahmah; Arnida; Khairunnisa, Amalia; Normaidah; Arini, Mifthah Dwi
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 11 No 1 (2026): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v11i1.2973

Abstract

Kokang (Lepisanthes amoena) is an endemic plant from Kalimantan traditionally used by the Dayak Tunjung community for skincare and wound treatment. Empirically, its leaves accelerate healing of skin problems such as acne scars and wounds within approximately two weeks. This research aimed to determine the total flavonoid content and evaluate the anti-inflammatory potential of the ethyl acetate extract of L. amoena leaves using the protein denaturation inhibition assay. The total flavonoid content was quantified spectrophotometrically using the aluminum chloride method, expressed as quercetin equivalents (QE). Anti-inflammatory activity was assessed by measuring the inhibition of protein denaturation, with sodium diclofenac as a positive control, and IC₅₀ values were calculated to compare activity levels. The results showed that the yield of the ethyl acetate extract of L. amoena leaves was 1.77%, with a total flavonoid content of 143.496 mg QE/g extract, and that it exhibited strong anti-inflammatory activity with an IC₅₀ value of 16.759 ppm. These findings scientifically support the traditional use of L. amoena leaves as an anti-inflammatory and wound-healing agent, highlighting their potential development for herbal or cosmeceutical formulations.