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All Journal Medali Jurnal : Media Dental Intelektual Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Al Makki Health Informatics Journal
Shafia, Arina
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Bay Leaf (Syzygium Polyanthum) Extract Effect on IL-10 and IL-6 Gene Expression in Traumatic Ulcer Shafia, Arina; Trisnadi, Setyo; Putra, Agung
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 17 No 2 (2023): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v17i2.6914

Abstract

The aims of this research is to prove the effect of bay leaf extract gel on IL-10 and IL-6 gene expression in traumatic ulcers. The research method using In vivo experimental study with a randomized posttest-only control group design. The total sample was 24 male Wistar rats, divided into four groups. Group K1 (given base gel), group K2 (given Kenalog in Orabase), group K3 (10% bay leaf extract gel), and group K4 (15% bay leaf extract gel) were given treatment for 5 days. IL-6 and IL-10 levels were tested using the One-Way Anova test, followed by the Tamhane Post Hoc test. This study revealed that there was a difference in IL-6 levels in the K4 group compared to the K1 group sig. (p = 0.007) and a significant difference in IL-10 levels in the K4 group compared to the K1 group. (p = 0.003) after being given topical treatment with bay leaf extract gel. The conclusion of this research is treatment with 15% bay leaf gel extract (Syzygium polyanthum) was proven to significantly increase IL-10 gene expression and decrease IL-6 gene expression in Wistar rats model of traumatic ulcers.
Description Of Primary School Student Behavior Post The 21 Days Tooth Brushing Program (Survey Of Students At Sdn Bangetayu Wetan 01 Semarang City) Putri, Salsabila Awalia; Amurwaningsih, Musri; Shafia, Arina
Jurnal Medali Vol 6, No 2 (2024): Media Dental Intelektual September 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.6.2.97-102

Abstract

Background: The high incidence of dental caries in elementary school-aged children was a public health problem. One effort to reduce the high rate of dental caries was through a 21-day tooth brushing program. It was hoped that the behavior would form permanently and become a habit. The purpose is to find out the description of elementary school students' behavior after the 21-day tooth brushing program.Method: The type of research was descriptive observational. The population in this study was elementary school students at SDN Bangetayu Wetan 01 Semarang City, totaling 386 students from grades 1 to 6. The sampling technique used was a total sampling technique which was in accordance with research inclusion and exclusion criteria, resulting in 105 samples. Data were subjected to descriptive statistical analysis.Result:The study showed that changes in dental and oral health maintenance behavior after the 21-day tooth brushing intervention were mostly in the sufficient category (49.5%). The majority of students' 21-day tooth brushing practice was in the routine category (82.9%). Conclusion: The most common characteristics of respondents were female (62.9%) and 10 years old (24.8%).Through the 21-day tooth brushing program, the students of SDN Bangetayu Wetan 01 Semarang City formed dental and oral health maintenance behavior.
Multisymptom Oral Presentation in Type II Diabetes Mellitus: A Case of Candidiasis, Xerostomia, and Burning Mouth Syndrome Shafia, Arina
Al Makki Health Informatics Journal Vol. 3 No. 5 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/sbrbap90

Abstract

Background: Oral candidiasis is a fungal infection of the tongue and oral mucosa caused by Candida species, characterized by overgrowth and superficial tissue invasion. One of the main predisposing factors is an immunocompromised state such as type II diabetes mellitus. Fungal infections in diabetic patients may be associated with additional oral symptoms, including Burning Mouth Syndrome (BMS) and xerostomia. Case Presentation: A 53-year-old male presented with a three-day history of burning sensation localized to the left side of the tongue. The complaint had not been previously treated. The patient reported a reduced sense of taste, limited to salty and spicy sensations, and persistent dry mouth. Medical history revealed a diagnosis of type II diabetes mellitus for six years, with discontinuation of antidiabetic medication over the past three months. Management and Outcome: The treatment plan included chlorinated dioxide mouthwash (used three times daily), xylitol (taken three times daily), nystatin oral suspension (applied four times daily), a single dose of fluconazole 150 mg, and Becomzet (taken once daily). The patient was instructed to maintain strict adherence to the medication regimen, practice good oral hygiene, and attend regular follow-ups. Improvement in symptoms was observed after consistent use of the prescribed therapy. Conclusion: Effective management of oral candidiasis in patients with poorly controlled type II diabetes mellitus, particularly when accompanied by Burning Mouth Syndrome and xerostomia, requires a comprehensive treatment approach. Success is largely dependent on accurate drug selection and patient compliance with therapy and oral hygiene practices. This case highlights the importance of addressing systemic factors in conjunction with local treatment to ensure resolution of symptoms and prevent recurrence.
Co-Authors Agung Putra Musri Amurwaningsih Putri, Salsabila Awalia Setyo Trisnadi