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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Medicina Biomedica Journal AL QUWWAH : Jurnal Pengabdian Masyarakat
Dwiyanti, Atika
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Religion Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Public Health Social Sciences Other

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Effects of AntiMycobacterium Tuberculosis Nanoherbal Legundy Leaf Extract (Vitex trifolia) Dwiyanti, Atika; Mulyani, Siti; Yulhan, Oche Axena; Lubis, Humairah Medina Liza; Roslina, Ance
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1: January 2021
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.6497

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Indonesia ranks 2nd largest in the world after India. Resistance to anti-tuberculosis drugs is one of the difficulties in treating tuberculosis. This research aim to determine the effectiveness of legundi (Vitex trifolia) leaf extract nanoherbal in killing Mycobacterium tuberculosis. This study was conducted with an experimental design using M. tuberculosis colonies taken from 25 samples of aspirate of tuberculosis patients with lymph nodes and then given the ethanol extract of legundi leaves (70% and 90%) with the process of making nanoparticle extracts. The evaluation of the observations was in the form of measuring the inhibition zone for bacterial growth which were categorized as weak ( 5mm), moderate (6-10mm), strong (11-20 mm) and very strong ( 21mm). The results of the study from 6 repetitions found that the inhibition zone category was 0% weak, 39% moderate, strong 52.3%, and very strong 8.7%. Comparison of the concentration of legundi leaf extract to the diameter of the bacterial growth inhibitory zone was analyzed using the Kruskal Wallis test, which found a significant relationship with p value = 0.000 ( 0.05). Legundi's leaf extract can be used as an antibacterial agent for M. tuberculosis. 
THE POTENTIAL OF EPIDERMAL GROWTH FACTOR RECEPTOR MOLECULES AS PREDICTORS OF CLINICAL STAGE AND PROGNOSIS OF SQUAMOUS CELL CARCINOMA IN MEDAN CITY Hasibuan, Ariq Muflih Halim; Pramesti, Tisya Amanah; Dwiyanti, Atika
Medicina Biomedica Journal Vol 1, No 1 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i1.8117

Abstract

Squamous cell carcinoma (SCC) is a non-melanoma skin malignant tumor originating from the suprabasal keratinocytes of the epidermis. Exposure to ultraviolet radiation is known to be one of the main triggers so that the place of predilection for this malignancy is an area that is often exposed to sunlight, especially the head and neck. Assessing the potential of the Epidermal Growth Factor Receptor (EGFR) molecule in predicting the clinical stage and prognosis of squamous cell carcinoma of the skin. This study used 40 samples of keratinized and non-keratinized Squamous Cell Carcinoma patients who were then given EGFR staining by immunohistochemistry. The result of staining on EGFR by immunohistochemistry is brown, whereas if it appears blue, the result is negative. The relationship of EGFR expression from 40 slides of SCC collected with EGFR immunohistochemical staining found 6 malignant tumors (15%) negative EGFR, then 14 malignant tumors (35%) showed weak grade (positive 1), 6 malignant tumors (15%) showed moderate expression level (positive 2) and 14 malignant tumors (35%) showed strong expression (positive 3). The test results showed a significant relationship between the level of EGFR with the clinical stage of squamous cell carcinoma as indicated by the value of p = 0.030 ( 0.05). The analysis was analyzed using the two-tailed Bivariate Correlation test. Expression of EGFR molecules on immunohistochemical staining of SCC of the skin can be used to determine the clinical stage of SCC of the skin.
Strategi Pelestarian Seni dan Budaya Nusantara Melalui Pendidikan Pada Anak-Anak Indonesia di Malaysia Andriani, Resti; Al jannah, Dina Masfufah; Sari, Inelea; Ramadhanty, Masayu Elmarisa; Ardiansyah, Fiki; Dwiyanti, Atika
AL QUWWAH : Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2025): Al Quwwah: Jurnal Pengabdian Masyarakat
Publisher : LP2M IAIN Syaikh Abdurrahman Siddik Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32923/aq.v5i1.5353

Abstract

This Community Service Program (KKN) is a form of service to the community and nation, not only in Indonesia but also to the Indonesian people in Malaysia. This program aims to introduce and preserve Indonesian arts and culture to Indonesian migrant children in Malaysia. Learning is given in the form of theory and practice. Art and cultural activities implemented in Malaysia include the introduction of traditional dance, folk songs, batik drawing, and traditional games. The results showed that the children were very fond and enthusiastic in the introduction and practice of Indonesian arts and culture.
Co-Authors Al jannah, Dina Masfufah Aminuyati Ance Roslina Andriani, Resti Ardiansyah, Fiki Hasibuan, Ariq Muflih Halim Humairah Medina Liza Lubis Pramesti, Tisya Amanah Ramadhanty, Masayu Elmarisa Sari, Inelea Yulhan, Oche Axena