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All Journal Majalah Kedokteran Bandung Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Anatomica (Anatomica Medical Journal) JURNAL IBNU SINA BIOMEDIKA Hasil Pengabdian Kepada Masyarakat JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Ihsan: Jurnal Pengabdian Masyarakat Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Jurnal Pandu Husada JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Ance Roslina
Universitas Muhammadiyah Sumatera Utara
Religion Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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MANFAAT PENAMBAHAN SULBAKTAM PADA SEFOPERAZON TERHADAP METISILIN RESISTEN STAPHYLOCOCCUS AUREUS POSITIF ENZIM BETALAKTAMASE Roslina, Ance
JURNAL IBNU SINA BIOMEDIKA Vol 2, No 1 (2018)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (507.536 KB) | DOI: 10.30596/isb.v2i1.1899

Abstract

Metisilin Resisten Staphylococcus aureus (MRSA) merupakan salah satu bakteri patogen penyebab infeksi. Bakteri ini penting karena resistensinya terhadap antibiotik betalaktam dan kecendrungannya menjadi resisten terhadap antibiotik lainnya. Penelitian ini dilakukan untuk penentuan Kadar Hambat Minimum (KHM) untuk mengetahui kadar inhibisi MRSA terhadap antibiotik Sefaperazon dan campuran Sefaperazon Sulbaktam. KHM Sefoperazon terhadap MRSA berkisar ≥50-100 %, sedang KHM Sefoperazon Sulbaktam ≥1,56-100%. Uji difusi metode Kirby Bauer dengan menggunakan konsentrasi yang sesuai dengan uji dilusi juga dengan menggunakan konsentrasi yang ada dipasaran. MRSA memberikan reaksi sensitif pada konsentrasi ≥ 6,25 %. Pada uji difusi terhadap konsentrasi obat dipasaran, Sefoperazon Sulbaktam konsentrasi 50/50 MRSA bereakai sensitif sebanyak (6,7%), konsentrasi 70/30 (33,4%), konsentrasi 60/40 (80%)  dan pada konsentrasi 80/20 (100%). Kesimpulan Sulbaktam dapat menurunkan resistensi bakteri penghasil β-laktamase.Kata kunci: Antibiotik Sefoperazon, Meticillin Resisten Staphylococcus aureus
UJI EFEKTIVITAS EKSTRAK KENCUR (Kaempferia galanga L.) TERHADAP PERTUMBUHAN CANDIDA ALBICANS SECARA IN VITRO Annisah, Rati; Batubara, Dian Erisyawanty; Roslina, Ance
JURNAL IBNU SINA BIOMEDIKA Vol 2, No 2 (2018)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (336.407 KB) | DOI: 10.30596/isb.v2i2.2598

Abstract

AbstrakLatar Belakang. Penyakit infeksi merupakan salah satu masalah kesehatan global baik di negara maju dan terlebih lagi di negara berkembang seperti Indonesia. Candida albicans merupakan suatu yeast patogen, secara normal ditemukan dalam tubuh manusia, spesies ini pada keadaan normal tidak berbahaya bagi tubuh.Namun, apabila terjadi gangguan seperti daya tahan tubuh yang lemah dan perubahan keseimbangan flora normal dapat menyebabkan penyakit kandidiasis. Kencur diketahui memiliki kandungan kimia seperti flavonoid, tannin, saponin dan minyak esensial yang bekerja sebagi anti fungal. Metode. Jenis penelitian yang dilakukan adalah penelitian eksperimental  post test only control group design disc difusiin method. Hasil. Hasil penelitian diperoleh bahwa ekstrak kencur memiliki daya hambat rata-rata terhadap pertumbuhan Candida albicans pada konsentrasi 40% dengan diameter resistansi 21,36 mm, konsentrasi 60% diameter hambatan 22,68 mm, konsentrasi diameter hambat 80% 24,74 mm, konsentrasi 100% diameter resistor 25,18 mm. Kesimpulan. Ekstrak Kencur memiliki ketahanan terhadap pertumbuhan Candida albicans secara in vitro.Kata Kunci: Ekstrak kencur, nystatin, candida albicans 
Effects of AntiMycobacterium Tuberculosis Nanoherbal Legundy Leaf Extract (Vitex trifolia) Dwiyanti, Atika; Mulyani, Siti; Yulhan, Oche Axena; Lubis, Humairah Medina Liza; Roslina, Ance
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1: January 2021
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.6497

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Indonesia ranks 2nd largest in the world after India. Resistance to anti-tuberculosis drugs is one of the difficulties in treating tuberculosis. This research aim to determine the effectiveness of legundi (Vitex trifolia) leaf extract nanoherbal in killing Mycobacterium tuberculosis. This study was conducted with an experimental design using M. tuberculosis colonies taken from 25 samples of aspirate of tuberculosis patients with lymph nodes and then given the ethanol extract of legundi leaves (70% and 90%) with the process of making nanoparticle extracts. The evaluation of the observations was in the form of measuring the inhibition zone for bacterial growth which were categorized as weak ( 5mm), moderate (6-10mm), strong (11-20 mm) and very strong ( 21mm). The results of the study from 6 repetitions found that the inhibition zone category was 0% weak, 39% moderate, strong 52.3%, and very strong 8.7%. Comparison of the concentration of legundi leaf extract to the diameter of the bacterial growth inhibitory zone was analyzed using the Kruskal Wallis test, which found a significant relationship with p value = 0.000 ( 0.05). Legundi's leaf extract can be used as an antibacterial agent for M. tuberculosis. 
Effects of AntiMycobacterium Tuberculosis Nanoherbal Legundy Leaf Extract (Vitex trifolia) Atika Dwiyanti; Siti Mulyani; Oche Axena Yulhan; Humairah Medina Liza Lubis; Ance Roslina
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1 (2021): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.6497

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Indonesia ranks 2nd largest in the world after India. Resistance to anti-tuberculosis drugs is one of the difficulties in treating tuberculosis. This research aim to determine the effectiveness of legundi (Vitex trifolia) leaf extract nanoherbal in killing Mycobacterium tuberculosis. This study was conducted with an experimental design using M. tuberculosis colonies taken from 25 samples of aspirate of tuberculosis patients with lymph nodes and then given the ethanol extract of legundi leaves (70% and 90%) with the process of making nanoparticle extracts. The evaluation of the observations was in the form of measuring the inhibition zone for bacterial growth which were categorized as weak (5mm), moderate (6-10mm), strong (11-20 mm) and very strong ( 21mm). The results of the study from 6 repetitions found that the inhibition zone category was 0% weak, 39% moderate, strong 52.3%, and very strong 8.7%. Comparison of the concentration of legundi leaf extract to the diameter of the bacterial growth inhibitory zone was analyzed using the Kruskal Wallis test, which found a significant relationship with p value = 0.000 (0.05). Legundi's leaf extract can be used as an antibacterial agent for M. tuberculosis. 
Immunocytochemical Study of Rabbit-Polyclonal to Mycobacterium Tuberculosis, AB905: Improving Diagnostic of Tuberculous Lymphadenitis Humairah Medina Liza Lubis; Emni Purwoningsih; Ance Roslina; Muhammad Al Anas
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 2 (2021): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i2.11559

Abstract

Tuberculous lymphadenitis (TBLN) is the most common form of extrapulmonary tuberculosis. However, the optimal diagnosis using Fine-Needle Aspiration Cytology (FNAC) or excisional biopsy is uncertain. This research aims to improve the diagnostic of TBLN with FNAC and immunocytochemistry (ICC) compared to the response to antituberculosis therapy. The cross-sectional study involved 43 patients with the criteria for TBLN diagnosis based on the appropriate clinical history of tuberculosis and indicative cytological results. Immunocytochemical examination employed rabbit-polyclonal to Mycobacterium tuberculosis (MTB) antibody (AB905). The MTB expression was found in 35 out of 43 cases (81%) that appropriate cytological features of the tuberculosis process. Meanwhile, eight out of 43 cases (19%) did not express MTB. Diagnostic tests for lesions with a positive cytologic appearance of TBLN and ICC were compared to the response to anti-tuberculosis therapy, revealing the sensitivity, specificity, positive predictive value, and negative predictive value of 95.2%, 75%, 95.2%, and 17%, respectively. Besides, Fisher's exact tests utilized to identify the relationship between two variables; p 0.05 was considered significant. This research found immunocytochemical study was a sensitive and specific tool for improving the diagnostic of TBLN.
IDENTIFIKASI BAKTERI DAN JAMUR PADA AIR CONDITIONER (AC) DI RUANG PERKULIAHAN FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA UTARI SEPTIA DHARMA; ANCE ROSLINA
JURNAL ILMIAH MAKSITEK Vol 5 No 4 (2020): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Air Conditioner (AC) is one of the most common used facilities for air conditioning. Air conditioners that are rarely cleanedand poorly maintained are a convenient place for the breeding of microorganisms (bacteria and fungi), which hasimplications for the decline in human health and activity. The existence of microorganisms can be influenced by variousfactors, namely temperature, humidity, lighting, occupancy density, ventilation system, the nature and activities of individualsin the room. The purpose of this research was to identify the bacteria and fungal on Air Conditioners in the Faculty ofMedicine, University of Muhammadiyah North Sumatera class. This research was a descriptive observational study using 14samples of dust smears taken from the AC filter. Data analyzed used distribution table. Most of the grown bacteria was GramPositive Bacillus Subtilis are 10 samples (66.7%) and half of the identified mold growth was Penicillium sp. are 7 samples(50%). The highest number of colony found was 32 x 109 x 102 CFU/m3 and the lowest was 0,02 x 102 CFU/m3. There aremicroorganism growth found in the room AC with the most common bacteria found was Bacillus subtilis and the mostcommon fungal growth was Penicillium sp. Despite the growth, more than half the lecture room AC colony number still in therange for air quality qualification are 8 samples (57,1%).
UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN BELIMBING WULUH (AVERRHOA BILIMBI L) TERHADAP PERTUMBUHAN BAKTERI KLEBSIELLA PNEUMONIAE SECARA IN VITRO FIRSTY DWI HIDAYATI SIRAIT; YENITA .; ANCE ROSLINA; ILHAM HARIAJI
JURNAL ILMIAH MAKSITEK Vol 5 No 4 (2020): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Infection is the most common disease in Indonesia. Infection disesase are caused by microorganisms such as the Klebsiellapneumoniae. While in fact, many plants can be used as traditional medicine, one of those is the leaves of Cucumber tree(Averrhoa bilimbi L). This study aims to determine the inhibitory power of leaves of Cucumber tree (Averrhoa bilimbi L) ongrowth of Klebsiella pneumoniae in vitro. This study used an experimental method. The technique used to measureantibiotic activity is the method of disk diffusion and continued by Kruskal-Wallis test and Mann-Whitney test Leaves ofCucumber tree (Averrhoa bilimbi L) at concentrations of 40%, 60%, 80%, 100%, cefotaxime, and aquabidest shows no clearzone. Leaves of Cucumber tree (Averrhoa bilimbi L) does not have an inhibitory power against Klebsiella pneumoniae.
PENYAKIT - PENYAKIT PENYEBAB DEMAM PADA ANAK PENDERITA KEJANG DEMAM DI RS HAJI MEDAN PERIODE 2019 - 2020 MUTIARA YUSFAH PUTRI S; ANCE ROSLINA
JURNAL ILMIAH MAKSITEK Vol 6 No 2 (2021): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Infectious diseases are still found in children. It can manifest into seizures as a result of high fever. To find out the diseaseswhich cause fever in children with febrile seizure in Haji Hospital Medan. This is a descriptive observational study.The most frequent disease which causes febrile seizure were upper respiratory tract infections which were found in 34children (44,73%). Based on age, 70 children (53,43%) aged 1-2 years old had febrile seizure and based on gender, 79children (60,3%) were boys and 52 (39,69%) were girls. Febrile seizure was mostly found in children with upper respiratorytract infections, aged 1-2 years old and were mostly found in children.
HUBUNGAN TINGKAT STRES TERHADAP PERTUMBUHAN KOLONI CANDIDA ALBICANS PADA SEKRET VAGINA IBU RUMAH TANGGA DESA PEGAJAHAN KABUPATEN SERDANG BEDAGAI SHAFIRA ROZAANDITA; ANCE ROSLINA
JURNAL ILMIAH SIMANTEK Vol 3 No 3 (2019): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Stress is human psychological response or reaction when confronted with things that are considered has exceeded the limit or difficult to deal with. Psychological stress affects the hypothalamus which further affects the production of Corticotropin Releasing Hormone (CRH). CRH will affect the pituitary that produces Adreno Corticotropin Hormone (ACTH). ACTH then affects the adrenal glands that produce glucocorticoid hormones. Through the Hipotalamus Pitiutari Adrenal axis (HPA axis), there will be an increase in endogenous glucocorticoids, namely cortisol and catecholamines. The combination of these two hormones during stress is immunosuppressive and increases susceptibility to the growth of Candida albicans colonies in the vagina. Objective: This study aims to determine whether there is a relationship between stress levels with the growth of Candida albicans colonies in vaginal secretions of housewives. Method: The type of research used is descriptive analytic using cross sectional design. The number of samples in this study were 30 housewives. Sampling was done by using consecutive sampling technique. Data analysis was done by using Chi-Square statistic test. Results: Obtained from 30 samples, 8 people (26.7%) were found in normal state, 5 people (16.7%) with mild stress, 15 people (50%) with moderate stress and 2 people (11. 5%) with severe stress. As for the number of colonies of Candida albicans in vaginal secretions obtained 7 people (23.3%) had a normal amount of Candida albicans colonies and 23 people (76.7%) had an increased number of Candida albicans colonies. Chi-Square statistical test results from this study shows the results of the p-value = 0.001 Conclusion: There is a significant relationship between stress level with the growth of Candida albicans colonies in vaginal secretions of housewives.
POLA BAKTERI PADA ULKUS PENDERITA DIABETES MELITUS DAN UJI KEPEKAAN TERHADAP ANTIBIOTIK CEFTRIAXONE DAN COTRIMOXAZOLE DI RUMAH SAKIT MURNI TEGUH MEDAN DWINDA RAHMATUN AZHARI PINEM; ANCE ROSLINA
JURNAL ILMIAH SIMANTEK Vol 4 No 4 (2020): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Ulcers are a chronic complication of diabetes mellitus with a risk of ulcers as much as 12-25%. Antibiotics are used to treatexisting ulcers, but already resistance to antibiotic broad spectrum of penicillin and cephalosporin. An antibiotic sensitivitytest is carried out to choose which one to use according to the causative bacteria, to cut down the cost of drugs,hospitalization days, and the incidence of amputation. This study is an observasional descriptive study using a crosssectionaldesign by taking ulcer swab in DM patients in Murni Teguh Hospital Medan. The results of the study were obtainedfrom 22 samples identified as gram-negative bacteria were 72,8% and gram-positive bacteria which was 27,2). The twolargest bacteria were Klebsiella sp (31,8%) and Staphylococcus aureus (27,2%). All samples were resistant to ceftriaxoneand cotrimoxazole antibiotics. The most identified bacteria in the ulcer of patients with DM are Gram-negative bacteria withthe type Klebsiella sp and have been resistant to ceftriaxone and cotrimoxazole antibiotics.
Co-Authors Amelia Eka Damayanti Amelia Eka Damayanti Aminuyati ANNISA . ANNISA ANNISA Annisah, Rati Atika Dwiyanti AULIA RAHMI Ayunda Pratiwi L. Tobing Ayunda Pratiwi L. Tobing DANDI NOVTIARDI Dian Erisyawanty Batubara DWINDA RAHMATUN AZHARI PINEM Dwiyanti, Atika FIRSTY DWI HIDAYATI SIRAIT Harahap, Habib Al Rasyid Harahap, Sevani Ayu Humairah Medina Liza Humairah Medina Liza Lubis IHAM HARIAJI Ilham Hariaji Isra Thristy Karina Ramadhani KARINA RAMADHANI Muhammad Al Anas Muhammad Devi Fauzan Rizki Mutiara Yusfah Putri MUTIARA YUSFAH PUTRI S NADHILAH SARI NASUTION NUR HALIZA RASYID Nurfadly, Nurfadly Oche Axena Yulhan Purwoningsih, Emni Putra, Kevin Rhesa Putri, Nabilah Triana RIDHA SAKINAH SOLIN Sarirah, Munauwarus SHAFIRA ROZAANDITA Siti Mulyani TITIN NURJANAH UTARI SEPTIA DHARMA Yenita Yenita Yulhan, Oche Axena