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Effect of aloe vera on the proliferation phase of oral mucosal wound healing in rats Primasari, Ameta; Yendriwati, Yendriwati; Minasari, Minasari; Buaya, Erlin Kristiani; Madani, Sri Ayu Winda; Sembiring, Kartika Nabila; Hidayati, Rizka
Majalah Kedokteran Gigi Indonesia Vol 9, No 1 (2023): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.77682

Abstract

Aloe vera is known as a medicinal plant containing an active substance acemannan thought to play a role in accelerating wound healing. This study aims to determine the effect of aloe vera extract on the proliferation phase of oral mucosa wound healing in rats by looking at epithelial thickening, epithelial gaps closure, growth of new blood vessels, and connective tissue growth. This research is a pure experimental study with a post-test only control group design. On the left buccal mucosa of the mouth of 24 white Wistar rats (n = 24), an incision was made by scalpel with 10 mm length and 2.5 mm depth. The rats were divided into 4 groups: groups 1 and 2 as controls, while groups 3 and 4 were applied with aloe vera extract made by maceration technique. Wound tissue was observed histologically with Hematoxylin-Eosin staining under a microscope with an image analyzer for measuring the thickness of epithelium. The analysis of epithelial gap width used morphometry, and the number of capillaries was counted manually. Connective tissue thickness was measured with Image-J software. These were carried out on days 7 and 14 after treatment and the data were analyzed with the independent t-test and Mann-Whitney test. The results showed that aloe vera extract had no significant effect on epithelial thickening on day 7 (p = 0.701) nor on day 14 (p = 0.639), but a significant effect was shown on epithelial gaps closing (p = 0.049), connective tissue thickening (p = 0.004), and capillary increase on day 7 (p = 0.049). It could be concluded that aloe vera extract could potentially accelerate the epithelial gaps closure, connective tissue thickening, and capillary increase during the proliferation phase of the oral mucosa wound healing.
A Comparison of Yogurt and Probiotic Supplements Effects on the Hardness of Tooth Enamel: An In vitro Study: Perbandingan Pengaruh Yogurt dan Suplemen Probiotik terhadap Kekerasan Enamel Gigi: Studi in Vitro Primasari, Ameta; Alfarizi, Tengku Rizky; Minasari, Minasari; Yendriwati, Yendriwati; Hidayati, Rizka
Dentika: Dental Journal Vol. 25 No. 2 (2022): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/dentika.v25i2.8575

Abstract

The demineralization of tooth enamel, which can be triggered by acidic foods and drinks at pH < 5.5, can initiate dental caries. Yogurt and probiotic supplements are drinks that are often consumed to help digestive function and improve the immune system. However, both drinks have a low pH, thereby, a long time of consumption can trigger the demineralization process. This study aims to evaluate the enamel hardness after applying yogurt and probiotic supplements, which was carried out experimentally in a laboratory with a one-group post-test design. The sample used is 9 human maxillary premolars in each treatment group. The treatment group comprises the test material, such as yogurt and probiotic supplements, as well as one control group with artificial saliva. Dental samples were immersed in the test material for 96 hours, and the enamel hardness level was measured with a Micro Vickers Hardness tester. The T-paired test showed that soaking with yogurt does not significantly affect the hardness of the enamel, as indicated by a p-value of 0.016. However, the effect was significant in probiotic supplements, with p=0.004. The results showed that soaking with yogurt was not significantly different from probiotic supplements in reducing enamel hardness, as evidenced by the Post Hoc (LSD) test (p=0.464). Conclusively, yogurt decreased enamel hardness less than probiotic supplements.
Peningkatan Pengetahuan Kesehatan Reproduksi Remaja Melalui Edukasi Interaktif di SMAN 5 Banjarbaru: Improving Adolescent Reproductive Health Knowledge Through Interactive Education at SMAN 5 Banjarbaru Rahma, Amelia; Rahman, Fauzie; Arifin, Syamsul; Anggraini, Lia; Minasari, Minasari; Raisya, Raisya; Seambaga, Alvian Aditya; Shafarina, Helmaria; Adila, Nor Azizah; Cahyani, Sulis
Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Vol. 4 No. 1 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jppmi.v4i1.432

Abstract

Kesehatan reproduksi remaja adalah isu penting karena masa remaja ditandai oleh perubahan fisik, sosial, dan psikologis. Pada fase ini, remaja mulai mencari informasi seputar kesehatan reproduksi, namun sering kali terpapar informasi yang tidak akurat. Oleh karena itu, edukasi yang tepat sangat diperlukan untuk mencegah masalah seperti kehamilan tidak diinginkan, infeksi menular seksual, dan gangguan psikologis. Kegiatan pengabdian ini bertujuan mengevaluasi dampak penyuluhan kesehatan reproduksi di SMAN 5 Banjarbaru dan meningkatkan pemahaman siswa. Program dilaksanakan pada 22 Mei 2024 untuk 29 siswa kelas X-3, menggunakan metode ceramah interaktif, diskusi, serta presentasi multimedia seperti ppt, poster, dan video animasi. Pre-test dan post-test dilakukan untuk mengukur perubahan pengetahuan siswa. Hasil evaluasi menunjukkan 62% peserta mengalami peningkatan pengetahuan, dengan rata-rata skor naik dari 73,79 menjadi 82,75. Data pre-test dan post-test dianalisis menggunakan SPSS. Uji normalitas menunjukkan data tidak berdistribusi normal, sehingga analisis dilanjutkan dengan uji nonparametrik Wilcoxon untuk menguji perbedaan nilai secara signifikan dan didapatkan p < 0,001 sehingga terdapat perbedaan yang signifikan secara statistik antara skor pre-test dan post-test. Temuan ini menegaskan bahwa intervensi edukatif yang terstruktur dapat meningkatkan pemahaman remaja tentang kesehatan reproduksi, serta pentingnya edukasi berkelanjutan untuk mendukung kesehatan jangka panjang