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Brixia Score for Predicting Mortality and Length of Stay in COVID-19 Confirmed Patients at the Hospital in Bandung Dede Setiapriagung; Cice Tresnasari; Fajar Awalia Yulianto
Global Medical & Health Communication (GMHC) Vol 10, No 1 (2022)
Publisher : Universitas Islam Bandung

On March 11, 2020, the World Health Organization declared the COVID-19 pandemic. This disease damages the lung and resulting mild to severe pneumonia. This study aimed to determine the value of the Brixia score for predicting mortality and length of stay of COVID-19 confirmed patients. The study design was case-control with secondary data from digital medical records of COVID-19 confirmed patients (December 2020 to February 2021). All patients' chest x-rays (CXR) were scored using the Brixia score. Logistic regression and the Spearman rank correlation test were used to identify mortality and length of stay predictors. There were 636 subjects included in this study, with the proportion of deceased patients (case group) being 20.3% (95% CI=17.33, 23.59%). Most CXR findings had signs of pneumonia (95.1%), including ground-glass opacities (GGOs) mixed with consolidation. The distribution of GGOs and consolidation were most frequent in the peripheral of survived patients (83.9%), while the deceased group had peripheral involvements mixed with medial (45.0%) and bilateral (22.2%). The mean Brixia score in the group of decease patients was significantly higher than the group of survived patients (11.95 vs 6.73, p=0.00). Brixia score had an OR of 1.14, 95% CI=1.07, 1.21 after adjusting by age, SpO2 level, and comorbid. The chance of dying was higher than 50% if the Brixia score reached to score of 15 (probability=49%, 95% CI=41, 56%). However, the Brixia score has no significant correlation with length of stay (rho=0.05, p=0.24). In conclusion, the CXR Brixia score can predict mortality, but it can not predict the length of stay of hospitalized COVID-19 confirmed patients.

Scoping Review: Pengaruh Paparan Bensin terhadap Kadar ALT dan AST pada Pekerja SPBU Dinarita Sari Nurhalimah; Santun Bhekti Rahimah; Dede Setiapriagung
Jurnal Integrasi Kesehatan dan Sains Vol 3, No 1 (2021): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v3i1.7453

Paparan bensin sering dikaitkan dengan efek buruk pada tubuh termasuk kerusakaan pada hepar. Salah satu pekerja yang memiliki risiko tinggi terpapar bensin secara inhalasi adalah pekerja Stasiun Pengisian Bahan Bakar Umum (SPBU). Kerusakan hepar dapat diketahui dengan pemeriksaan fungsi hepar salah satunya pemeriksaan enzim hepar, yaitu ALT dan AST. Penelitian ini bertujuan mengetahui pengaruh paparan bensin terhadap kadar ALT dan AST pada pekerja SPBU. Metode penelitian menggunakan Scoping Review dengan mengindentifikasi, menganalisis, dan mengevaluasi artikel publikasi ilmiah yang sesuai dengan kriteria inklusi dan eksklusi, kriteria kelayakan sehingga diperoleh sebelas jurnal. Kata kunci yang digunakan “Gasoline workers” AND “ALT’ dengan artikel populasi pekerja SPBU, intevensi paparan bensin, perbandingan kelompok kontrol, dan hasil kadar ALT dan AST. Penelitian dilakukan pada Oktober sampai Desember 2020. Hasil penelitan didapatkan sebanyak sebelas artikel dengan empat artikel menyatakan ada perubahan signifikan pada ALT dan AST, dua artikel mengatakan hanya ALT yang mengalami perbedaan signifikan, dan lima artikel mengatakan tidak terdapat perubahan signifikan ALT dan AST. Kesimpulan penelitian terdapat perbedaan hasil ALT dan AST di berbagai artikel dapat dipengaruhi oleh faktor seperti variasi durasi dan konsentrasi bahan bakar terpapar, metode yang digunakan, perbedaan faktor lainnya seperti usia, jenis kelamin, BMI, merokok, konsumsi alcohol, atau pengabaian alat pelindung diri, kerusakan sel masif, serta dapat disebabkan oleh regenerasi sel hepar. Scoping Review: the Effect of Gasoline Exposure on ALT and AST Levels in Petrol Station AttendantsGasoline exposure often associated to adverse health effects including hepatic injury. Petrol station attendants are the most risky exposed to gasoline by inhalation due to occupational. Hepatic injury may be identified by examining the liver function such as liver enzyme, ALT and AST. This study aims to determine effect gasoline exposure on AST and ALT levels in petrol station attendants. This research method used Scoping Review by identifying, analyzing, and evaluating scientific publication articles that is in accordance with the inclusion and exclusion criteria, eligibility criteria thus eleven articles were obtained. Keyword used are “Gasoline workers” AND “ALT”, articles relevant to petrol station attendants population, gasoline exposure, control group, and ALT and AST levels. This research was conducted from October to December 2020. The result showed from eleven articles, four articles reported there was a significant differences in AST and ALT, two articles reported there was significant difference in ALT, and five articles reported there was no significant change in ALT nor AST. The conclusion of this study is difference in result may be influenced by other factor such as variation, duration, concentration of exposed fuel, method used, age, sex, smoking, alcohol consumption or neglect of personal protective equipment, massive cell destruction, also liver cell regeneration may take a role.

Systematic Review: Hubungan Personal Hygiene dengan Kejadian Skabies di Pondok Pesantren Egidia Setya Fitriani; Ratna Dewi Indi Astuti; Dede Setiapriagung
Jurnal Integrasi Kesehatan dan Sains Vol 3, No 1 (2021): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v3i1.7390

Skabies adalah penyakit yang masih menjadi masalah kesehatan global. Penyakit skabies masuk ke dalam 12 penyakit yang sering terjadi di Indonesia. Skabies dapat terjadi akibat beberapa faktor risiko salah satunya adalah personal hygiene. Penelitian ini bertujuan mengetahui hubungan personal hygiene dengan kejadian skabies di Pondok Pesantren. Metode adalah Systematic review dengan kata kunci “personal hygiene” dan “kejadian skabies” pada santri di Pondok Pesantren dengan desain penelitian cross-sectional sesuai dengan kriteria inklusi dan eksklusi, dilakukan skrining menggunakan kriteria kelayakan ( Eligibility Criteria ) yang terdiri atas P (Population) santri di Pondok Pesantren, I (Intervention) kuesioner untuk menilai personal hygiene, C (Comparation) membandingkan personal hygiene yang baik dengan buruk dan O (Outcome) hubungan personal hygiene dengan kejadian skabies serta artikel yang lolos critical apprisal. Hasil penelitian, penderita skabies di Pondok Pesantren sebesar 46,8% dengan confidence interval 95% adalah 44,8 – 48,8%, personal hygiene yang buruk pada santri sebanyak 42,5% dengan confidence interval 95% adalah 40,4 – 44,6% dan terdapat 24 dari 27 artikel menyatakan terdapat hubungan personal hygiene dengan kejadian skabies di pondok pesantren Kesimpulan, personal hygiene berhubungan dengan kejadian skabies. Systematic review: the Relationship of Personal Hygiene and the Incidence of Scabies in Boarding SchoolScabies is a disease that is still a global health problem. Scabies is one of the 12 most common diseases in Indonesia. Scabies can occur due to several risk factors, one of which is personal hygiene. Purpose: This study aims to determine the relationship of personal hygiene with the incidence of scabies in Islamic boarding schools. Methods: Systematic review with the keywords "personal hygiene" and "scabies incidence" in students at Islamic boarding schools with a cross-sectional research design in accordance with inclusion and exclusion criteria, screening using Eligibility Criteria. consisting of P (Population) of students at Islamic boarding schools, I (Intervention) questionnaire to assess personal hygiene, C (Comparation) comparing good and bad personal hygiene and O (Outcome) the relationship of personal hygiene with the incidence of scabies and articles that pass critical apprisal. Results: The number of scabies sufferers in Islamic boarding schools was 46.8% with a 95% confidence interval was 44.8 – 48.8%, poor personal hygiene among the students was 42.5% with a 95% confidence interval was 40.4 – 44.6% and 24 out of 27 articles stated that there was a relationship between personal hygiene and the incidence of scabies in Islamic boarding schools. Conclusion: Personal hygiene is related to the incidence of scabies.

Scoping Review: Hubungan Index Keparahan Gambaran Chest X-Ray dengan Usia pada Pasien Terkonfirmasi COVID-19 Naya Valenski; Yani Triyani; Dede Setiapriagung
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.1351

Abstract. One of the impacts of COVID-19 infection is the manifestation in the lungs due to the COVID-19 virus attacks the respiratory tract. Therefore, radiographic examination is needed for monitoring the severity of the lungs of patients with confirmed COVID-19. The severity of the Chest X-Ray can be calculated using an assessment score such as Brixia Score. Factors that affect the severity of chest X-Ray include age in patients with confirmed COVID-19. Older age increases the severity of Chest X-Ray because the immune system declines with age. Thus, the aim of this study was to determine the relationship between the severity index of Chest X-Ray with age in patients with confirmed COVID-19. The study was taken using the scoping review method with a sample of international scientific articles that met the eligibility criteria (elegible). The results in this study were taken from three databases, namely Science Direct, Springer Link and Proquest as well as the Google Scholar scientific publication search feature with 795 initial search results and three eligible articles. The results of three articles, one article uses the RALE (Radiographic Assessment of Lung Edema) score with the results that there is a relationship between the severity of Chest X-Ray and the age of patients with confirmed COVID-19, namely the higher the age, the higher the severity of the Chest X-Ray. The other two articles used the Brixia score with similar results using the RALE score. The conclusion of this study shows that there is a relationship between the severity of Chest X-Ray and age in patients with confirmed COVID-19. Abstrak. Salah satu dampak infeksi COVID-19 adanya manifestasi pada organ paru dikarenakan virus COVID-19 menyerang saluran pernapasan. Oleh karena itu, diperlukan pemeriksaan radiografi untuk monitoring keparahan pada paru pasien terkonfirmasi COVID-19. Keparahan pada gambaran Chest X-Ray dapat dihitung dengan menggunakan skor penilaian seperti skor Brixia. Faktor yang mempengaruhi tingkat keparahan gambaran Chest X-Ray antara lain usia pada pasien terkonfirmasi COVID-19. Usia yang lebih tua meningkatkan tingkat keparahan gambaran Chest X-Ray disebabkan oleh sistem imun yang menurun seiring bertambah usia. Tujuan penelitian untuk mengetahui hubungan indeks keparahan gambaran Chest X-Ray dengan usia pada pasien terkonfirmasi COVID-19. Penelitian diambil dengan metode scoping review dengan sampel artikel ilmiah internasional yang memenuhi kriteria kelayakan (elegible). Hasil pada penelitian ini diambil dari tiga database yaitu Science Direct, Springer Link dan Proquest serta fitur pencarian publikasi ilmiah Google Scholar dengan hasil pencarian awal terdapat 795 dan artikel yang memenuhi kelayakan (eligible) ada tiga artikel. Hasil dari tiga artikel, satu artikel menggunakan skor RALE (Radiographic Assesment of Lung Edema) dengan hasil terdapat hubungan antara tingkat keparahan gambaran Chest X-Ray dengan usia pasien terkonfirmasi COVID-19 yaitu semakin tinggi usia maka semakin tinggi tingkat keparahan gambaran Chest X-Ray. Dua artikel lainnya menggunakan skor Brixia dengan hasil yang sama dengan menggunakan skor RALE. Kesimpulan penelitian ini menunjukan bahwa terdapat hubungan antara tingkat keparahan gambaran Chest X-Ray dengan usia pada pasien terkonfirmasi COVID-19.

Kemungkinan Adaptive Coping Styles dalam Mencegah Kejadian Depresi pada Mahasiswa selama Pandemi COVID-19: Kajian Pustaka Rakanda Muhammad Naufal Pratomo; Putri Qintara Choirunnisa; Nugraha Sutadipura; Dede Setiapriagung
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.2207

Abstract. The COVID-19 pandemic has caused a bad psychological response in all groups of society, especially young adult university students. This is because there are stressors that come from the environment, such as someone who is separated from his family, lives in a place that is prone to COVID-19 transmission, or face-to-face learning turns into online learning. These stressors can cause psychological symptoms, namely depression. Major Depressive Disorder (MDD) or depression is a mood disorder that is chronic and can spread, characterized by persistently low mood, hopelessness, anhedonia, loss of energy, and cognitive dysfunction. There are discrete episodes lasting at least 2 weeks that can produce marked changes in effects on cognition, neurovegetative function, and interepisode remission. Depression is caused by reduced expression of the NR3C1; methylation of the BDNF gene; methylation of the SLC6A4 promoter. Psychosocially caused by developmental predisposition and life events. As many as 1 in 5 groups of young adults suffer from depression and about 6.2% want to commit suicide. Adaptive coping styles play a role in intervening these mechanisms in the medial prefrontal cortex and nucleus accumbens. Thus, stressors can be handled properly and can prevent symptoms of depression in university students during the COVID-19 pandemic. Abstrak. Pandemi COVID-19 menimbulkan respons psikologis yang buruk pada semua kelompok masyarakat, terutama kelompok mahasiswa usia dewasa muda. Hal tersebut disebabkan karena terdapat stresor yang berasal dari lingkungan, seperti seseorang yang terpisah dengan keluarga, tinggal ke tempat yang rentan adanya penularan COVID-19, atau pembelajaran tatap muka berubah menjadi pembelajaran dalam jaringan (daring). Stresor tersebut dapat menyebabkan gejala psikologis, yaitu depresi. Major Depressive Disorder (MDD) atau depresi adalah gangguan mood yang bersifat kronis dan dapat menyebar, ditandai dengan mood yang terus-menerus rendah, putus asa, anhedonia, kehilangan energi, dan disfungsi kognitif. Terdapat episode diskrit paling tidak selama 2 minggu yang dapat membuat perubahan jelas dalam pengaruh pada kognisi, fungsi neurovegetative, dan remisi interepisode. Depresi disebabkan oleh ekspresi gen NR3C1 yang berkurang; methylation pada gen BDNF; methylation pada SLC6A4 promoter. Secara psikososial disebabkan oleh developmental predisposition dan life events. Sebanyak 1 dari 5 kelompok dewasa muda menderita depresi dan sekitar 6,2% ingin bunuh diri. Adaptive coping styles berperan dalam mengintervensi mekanisme tersebut pada medial prefrontal cortex dan nucleus accumbens, sehingga stresor dapat ditangani dengan baik dan dapat mencegah gejala depresi pada mahasiswa selama Pandemi COVID-19.

Hubungan Antara IMT dengan Keluhan Lower Back Pain pada Mahasiswa FK Unisba Dimas Muhammad Farhan; Dede Setiapriagung; Yuniarti
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6259

Abstract. Low Back Pain (LBP) is a pain complaint that often occurs in the world, especially in Indonesia. Body Mass Index (BMI) is one of the risk factors for someone to experience LBP and there has been no research on the relationship between BMI and LBP complaints in student of the faculty of medicine, Bandung Islamic University. This study aims to analyze whether there is a relationship between body mass index and LBP complaints in FK UNISBA students. This study used an analytic observational method with a cross-sectional approach. The sampling method is by using probability sampling technique with random sampling. The number of samples according to inclusion enumeration was 85 people with measurements including measurements of height, weight and LBP complaints. The average age of the respondents was 18 years old as many as 43 people (50.6%) and based on gender the majority were women as many as 54 people (63.5%). The average BMI of the respondents was in the normal BMI category, namely 35 people (41.2%). LBP complaints to respondents, namely as many as 58 people (68.2%) did not experience LBP complaints. Bivariate analysis using the chi square test obtained BMI results with LBP complaints (p: 0.182) > 0.05 which means that there is no relationship between BMI and LBP complaints in FK UNISBA students. Abstrak. Low back Pain (LBP) merupakan keluhan nyeri yang sering terjadi di dunia terutama di Indonesia. Indeks massa tubuh (IMT) merupakan salah satu faktor risiko seseorang untuk mengalami LBP dan belum ada penelitian tentang hubungan antara IMT dengan keluhan LBP pada mahasiswa FK UNISBA. Penelitian ini bertujuan untuk menganalisis apakah terdapat hubungan antara IMT dengan keluhan LBP pada mahasiswa FK UNISBA. Penelitian ini menggunakan metode analitik observasional dengan pendekatan cross-sectional. Cara mengambilan sampel adalah dengan teknik probability sampling dengan jenis random sampling. Jumlah sampel yang sesuai dengan kriteria inklusi sebanyak 85 orang dengan pengukuran meliputi pengukuran tinggi badan, berat badan dan keluhan LBP. Usia rata-rata responden adalah berusia 18 tahun sebanyak 43 orang (50.6%) dan berdasarkan jenis kelamin sebagian besar perempuan sebanyak 54 orang (63.5%). Indeks massa tubuh rata-rata pada responden adalah kategori IMT normal yaitu sebanyak 35 orang (41.2%). Keluhan LBP pada responden yakni sebanyak 58 orang (68.2%) tidak mengalami keluhan LBP. Analisis bivariat menggunakan uji chi square mendapatkan hasil IMT dengan keluhan LBP (p: 0.182) > 0.05 dengan hal ini disimpulkan bahwa tidak terdapat hubungan antara IMT dengan keluhan LBP pada mahasiswa FK UNISBA.

PEMBERDAYAAN TOKOH MASYARAKAT DALAM PENDAMPINGAN PENCEGAHAN PENYAKIT REUMATIK DEGENERATIF DI KAMPUNG PERENG DESA PANGAUBAN KECAMATAN PACET KABUPATEN BANDUNG Muhammad Iqbal; Dede Setiapriagung; Nuri Amalia; Yani Triyani
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 7, No 1 (2023): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v7i1.13166

ABSTRAKHasil survey masyarakat di kampung Pereng, Desa Pangauban Kecamatan Pacet Kabupaten Bandung sekitar 70% terdiri dari orang tua yang sering mengeluhkan penyakit degeneratif terutama reumatik, namun jarang berobat ke puskesmas. Kegiatan pengabdian di daerah tersebut bertujuan memberikan solusi permasalahan dengan pendampingan tokoh masyarakat untuk mengenal cara hidup sehat islami sebagai salah satu pencegahan penyakit yang sering dikeluhkan warga. Metode yang dilakukan pada tahapan awal adalah penjaringan kesehatan warga untuk mengetahui jenis penyakit yang paling banyak ditemukan. Tahapan selanjutnya adalah melakukan pendampingan berupa dialog interaktif kepada para tokoh masyarakat sebagai corong kesehatan masyarakat, dan dilakukan pre dan post test untuk menilai pengetahuan tentang penyakit degeneratif. Kegiatan dilakukan di mesjid kampung Pereng, bulan Agustus–Oktober 2022. Hasil penjaringan kepada 135 orang, ditemukan warga berusia >61 tahun sebanyak 106 warga (79%), dan penyakit terbanyak yang ditemukan adalah jaringan otot dan sendi 32 orang (24%), kedua kasus hipertensi 24 orang (18%), hal ini sangat berhubungan dengan gaya dan pola hidup yang masih belum baik. Sebagai kesimpulan pendampingan yang dilakukan dapat menambah pengetahuan tentang pencegahan penyakit degeneratif kepada para tokoh masyarakat, yang terlihat dari adanya peningkatan skor pengisian post test setelah pendampingan dibandingkan pre test. Kata kunci: pemberdayaan; pencegahan penyakit degenerative; tokoh masyarakat. ABSTRACTThe results of a community survey in Pereng, Pangauban Village, Pacet District, Bandung Regency, around 70% consisted of parents who often complained of degenerative diseases, especially rheumatism, but rarely went to the puskesmas. Community service aim to provide solutions to problems by assisting community leaders to know the healthy Islamic way of life as one of the preventions of diseases often complained. The method used in the early stages was a citizen health screening to find the diseases most commonly found. The next stage is to assist community leaders as public health mouthpieces, according by interactive dialogue and to fill in the pre and post-tests to assess knowledge about degenerative diseases. The activity was carried out at the Pereng village mosque, August–October 2022.The screening results found 135 residents, 106 residents aged >61 years (79%), and most of the diseases found were muscle and joint tissue (rheumatism) in 32 people (24%), this is very related to lifestyle and lifestyle which is still not good. In conclusion, the assistance provided can increase knowledge about preventing degenerative diseases to community leaders, which can be seen from the increase in post-test filling scores after mentoring compared to the pre-test. Keywords: community leaders; empowerment; prevention of degenerative diseases

Clozapine Efektif pada Pasien Skizofrenia yang Resisten terhadap Pengobatan Natasha Syifa Rachman; Siti Annisa Devi Trusda; Dede Setiapriagung
Bandung Conference Series: Medical Science Vol. 1 No. 1 (2021): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v1i1.67

Abstract. Schizophrenia is a neuropsychiatric disorder with a high morbidity rate. One of the therapies to treat schizophrenic patients is to use antipsychotics such as typical and atypical drugs. Typical antipsychotics are the first line of treatment for schizophrenia but recently resistance is often developed, so that therapy is switched to atypical antipsychotics. Clozapine is the most commonly used atypical antipsychotic. The aim of this study was to determine the effectiveness of clozapine in schizophrenic patients who were resistant to other antipsychotics. The method used in this study is a scoping review, with research articles from international journals that meet the inclusion and exclusion criteria. This article was then selected using the PRISMA diagram by considering Population (schizophrenic patients), Intervention (giving clozapine), Comparison (placebo or other antipsychotic), Outcome (reduction in psychotic symptoms), Study (RCT, clinical trial, case report, and meta analysis). The results of this study indicate that clozapine is one of the most effective atypical antipsychotics compared to other antipsychotic drugs to treat patients suffering from schizophrenia, especially for schizophrenic patients who are resistant to other antipsychotic treatments. Abstrak. Skizofrenia merupakan gangguan neuropsikiatik dengan angka morbiditas yang masih tinggi. Salah satu terapi untuk menangani pasien skizofrenia adalah dengan menggunakan antipsikotik berupa tipikal dan atipikal. Antipsikotik tipikal menjadi lini pertama pengobatan skizofrenia. Dewasa ini berkembang penelitian bahwa sering terjadi resistensi terhadap antipsikotik tipikal, sehingga terapi beralih ke antipsikotik atipikal. Clozapine merupakan antipsikotik atipikal yang paling sering digunakan. Tujuan penelitian ini adalah mengetahui efektifitas clozapine terhadap pasien skizofrenia yang resisten terhadap antipsikotik lain. Metoda yang digunakan dalam penelitian ini adalah scoping review, dengan bahan penelitian artikel dari jurnal internasional yang memenuhi kriteria inklusi dan eksklusi. Artikel ini kemudian diseleksi menggunakan diagram prisma dengan mempertimbangkan Population (pasien skizofrenia), Intervention (pemberian clozapine), Comparison (plasebo atau antipsikotik lain), Outcome (penurunan gejala psikotik), Study (RCT, clinical trial, case report, dan meta analysis). Hasil penelitian ini menunjukan bahwa clozapine merupakan salah satu antipsikotik atipikal yang paling efektif dibandingkan dengan obat antipsikotik lainnya untuk mengobati pasien yang menderita skizofrenia, khususnya untuk pasien skizofrenia yang resisten terhadap pengobatan antipsikotik lain.

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