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All Journal Medula JK Unila (Jurnal Kedokteran Universitas Lampung)
Neema Putri Prameswari
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Agriculture, Biological Sciences & Forestry Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Prediktor Komplikasi Dengue Shock Syndrome (DSS) pada Pasien Pediatri dengan Dengue Hemorrhagic Fever (DHF) Ahmad Arkan Ichsan; Khairun Nisa Berawi; Neema Putri Prameswari; Ratu Nirmala Wahyunindita
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.42

Abstract

Dengue Hemorrhagic Fever (DHF) are tropical infectious diseases prevalent in tropical, subtropical and temperate climate countries, complications of DHF that leads to Dengue Shock Syndrome (DSS) may have drastic implications towards the mortality of pediatric patients. Ongoing assessment is still proceeding on Risk factors for the patient’s progression to DSS and there are several predictors utilized on patient follow-up that may indicate high risk of clinical symptom progression to DSS. Several predictors are identified to be the female gender, age between 6-10 years, hepatomegaly, late clinical management, heavy plasma leakage, obesity, spontaneous bleeding, gastrointestinal bleeding and presentations of ascites and pleural effusion. Several lab examinations include leucopenia, prolonged aPTT, low platelet count, thrombocytopenia, hematocrit of ≥ 40, low lipid profile, hypoalbuminemia, hypoproteinemia. There are also other predictors identified such as high Troponin T levels, NS1Ag expression, NK and NKT gene expression, elevated Vitamin D levels, Fatty acid levels. high sTM levels, elevated Chymase enzyme serum levels and elevated lactate serum levels. The usage of machine learning and algorithms may also prove useful in predicting DSS complications through pattern identification. There is a wide array of current and new methodologies to predict DHF progression to DSS, and further review analysis may be needed to determine concrete indicators for predicting DHF progression to DSS. Newer methods may prove useful, and would need further testing to ensure its capabilities on predicting DSS.
Manajemen Gigitan Ular Risal Wintoko; Neema Putri Prameswari
Jurnal Kedokteran Universitas Lampung Vol 4, No 1 (2020): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v4i1.2765

Abstract

Indonesia adalah salah satu negara beriklim tropis yang masyarakatnya memiliki aktivitas pertanian yang tinggi, hal tersebut merupakan faktor potensial tingginya kasus gigitan ular di Indonesia. Gigitan ular merupakan kegawatdaruratan medis yang dapat menyebabkan disabilitas permanen hingga kematian. Gigitan ular merupakan kasus penyakit daerah tropis yang banyak terabaikan menurut World Health Organization. Hal ini dapat dikarenakan kurangnya laporan epidemiologi, program kontrol, dan pedoman nasional penatalaksanaan gigitan ular yang tersedia. Padahal, jumlah kasus gigitan ular di Asia Tenggara dinilai cukup tinggi. Untuk itu, dibutuhkan upaya untuk mengurangi morbiditas dan mortalitas gigitan dengan upaya preventif dan kuratif, termasuk didalamnya adalah manajemen yang komprehensif untuk menjamin penatalaksanaan yang tepat, aman, dan efektif.Kata Kunci: Gawat darurat, gigitan ular, penatalaksanaan
Co-Authors Ahmad Arkan Ichsan Khairun Nisa Ratu Nirmala Wahyunindita Risal Wintoko