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Penurunan Kadar Kolesterol Total Darah sebagai Resiko Dislipidemia pada Lansia yang Mengikuti Senam Jantung Sehat Berawi, Khairun Nisa
Jurnal Kedokteran Universitas Lampung Vol 1, No 2 (2016): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v1i2.1620

Abstract

Dislipidemia adalah salah satu faktor resiko utama terjadinya penyakit jantung koroner, yang menjadi penyebab kematian utama di dunia. Dislipidemia ditandai dengan peningkatan total serum kolesterol, LDL-C dan peningkatan kadar HDL-C. kolesterol total biasanya paling berhubungan dengan insiden dislipidemia. Gangguan koletserol ini semakin meningkat dengan bertambahnya usia dan diatas 60 tahun yang masuk golongan lanjut usia kasusnya semakin banyak. Tingginyakolesterol plasma merupakan salah satu faktor resiko terbesar yang berhubungan dengan penyakit kardiovaskuler. Latihan aerobik intensitas sedang seperti pada senam jantung sehat mampu menurunkan kadar kolesterol total pada lansia sehingga membantu mengurangi resiko terjadinya dislipidemia yang berkontribusi menjadi penyakit kardiovaskuler. Latihan ini meningkatkan aktifitas lipoprotein lipase yang membantu katabolisme trigliserida dalam partikel lemak darah.Penelitian ini bertujuan untuk mengetahui pengaruh senam jantung sehat terhadap kolesterol total pada lansia di Panti Lansia Tresna Werdha Bhakti Yuswa, Natar, Lampung Selatan. Perlakuan senam jantung sehat diberikan selama 2 bulan berturut dengan frekuensi 2-3 kali seminggu durasi persesi 30 menit. Penelitian menggunakan metode eksperimental predan post-test design dengan subjek 30 orang lansia. Nilai rerata kolesetrol total sebelum senam 193,23 mg/dl dan sesudah senam 189,43 mg/dl. Nilai rerata kolesterol total sebelum senam 31,535 mg/dl dan sesudah senam 30,177 mg/dl. Hasil uji t untuk kadar kolesterol total didapatkan p-value = 0,007 (α≤0,05). Simpulan : pemberian senam jantung sehat pada lansiadapat menurunkan resiko dislipidemia dengan menurunkan kadar kolesterol total darah. [JK Unila. 2016; 1(2)]Kata kunci: kolesterol total, lansia, senam jantung sehat
Hubungan Obesitas Sentral dengan Hitung Jenis Leukosit pada Laki-Laki Dewasa di Lingkungan Universitas Lampung Diva Iole Humaira; Khairun Nisa Berawi; Chicy WIdya Morfi
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.16

Abstract

Obesity is a condition characterized by excessive accumulation of fat in the body. One form of obesity is central obesity which is characterized by the accumulation of fat, especially in the abdomen, and is more common in men. Central obesity has a stronger correlation with various diseases as a result of chronic inflammatory reactions that occur in adipose tissue. This ongoing inflammatory process will cause changes in various immunological parameters, one of which is leukocyte count. This study aims to determine the relationship between central obesity and leukocyte count in adult obese men. This research uses a cross-sectional approach. 59 study subjects were consisting of 39 central obese men and 20 non-obese central men. Venous blood samples were used in the calculation of differential counts and calculated Manually by microscope. The results showed a significant association between central obesity with neutrophil (p= 0,01), monocyte (p= 0,031) and lymphocyte counts (p= 0,003) but eosinophils and basophils did not have a significant relationship (p= 0,106 and p= 0,166). There is a relationship between central obesity with neutrophil type counts, monocytes, and lymphocytes in adult males with central obesity but eosinophils and basophils have no relationship.
Hubungan Obesitas dengan Perubahan Perilaku pada Remaja di SMPN 4 Bandar Lampung Putri Giani Purnamasari; Khairun Nisa Berawi; Fitria Saftarina
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.24

Abstract

Obesity (overweight) is a fundamental disease from non-communicable diseases such as diabetes, hypertension, and cardiovascular disease who still becomes a major health issue in Indonesia and the world. The teenager is a transition period that involves changes in physiological, psychological, social, and can develop into overweight or obesity. The fear of being obese is more common in girls than boys, and this explains why an effort to lose weight is mostly found in girls. This study aimed to determine the relationship between obesity and teenagers' behavioral changes in 14-16 years old of SMPN 4 Bandar Lampung students. It was a comparative analytic with a cross-sectional study. The sampling method used a case-control and using a questionnaire as a measuring tool. Data were then analyzed with a chi-square test. The study was conducted against 77 respondents with 48 respondents (62.3%) who were obese and 29 respondents (37.7%) not obese. While as many as 20 respondents (26.0%) had problematic behavior and 57 respondents (74.0%) did not have problematic behavior. The result of the chi-square test with a p-value was 0.015. There was a significant association between obesity with the teenager's behavior change in SMP Negeri 4 Bandar Lampung.
Prediktor Komplikasi Dengue Shock Syndrome (DSS) pada Pasien Pediatri dengan Dengue Hemorrhagic Fever (DHF) Ahmad Arkan Ichsan; Khairun Nisa Berawi; Neema Putri Prameswari; Ratu Nirmala Wahyunindita
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.42

Abstract

Dengue Hemorrhagic Fever (DHF) are tropical infectious diseases prevalent in tropical, subtropical and temperate climate countries, complications of DHF that leads to Dengue Shock Syndrome (DSS) may have drastic implications towards the mortality of pediatric patients. Ongoing assessment is still proceeding on Risk factors for the patient’s progression to DSS and there are several predictors utilized on patient follow-up that may indicate high risk of clinical symptom progression to DSS. Several predictors are identified to be the female gender, age between 6-10 years, hepatomegaly, late clinical management, heavy plasma leakage, obesity, spontaneous bleeding, gastrointestinal bleeding and presentations of ascites and pleural effusion. Several lab examinations include leucopenia, prolonged aPTT, low platelet count, thrombocytopenia, hematocrit of ≥ 40, low lipid profile, hypoalbuminemia, hypoproteinemia. There are also other predictors identified such as high Troponin T levels, NS1Ag expression, NK and NKT gene expression, elevated Vitamin D levels, Fatty acid levels. high sTM levels, elevated Chymase enzyme serum levels and elevated lactate serum levels. The usage of machine learning and algorithms may also prove useful in predicting DSS complications through pattern identification. There is a wide array of current and new methodologies to predict DHF progression to DSS, and further review analysis may be needed to determine concrete indicators for predicting DHF progression to DSS. Newer methods may prove useful, and would need further testing to ensure its capabilities on predicting DSS.
Hubungan Tahap Pengobatan dengan Kualitas Hidup Pasien Multidrug-resistant Tuberculosis di RSUD Dr. H. Abdul Moeloek Provinsi Lampung Muhammad Rifki Pratama; Asep Sukohar; Khairun Nisa Berawi
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.48

Abstract

Tuberculosis (TB) is the number one infectious disease in the world as the most frequent cause of death. TB infects 10 million people each year and becomes the 10th highest cause of death in the world.Multidrug-resistant Tuberculosis (MDR-TB) is a type of TB germ resistance against at least two first-line anti-tuberculosis (OAT) drugs. MDR-TB treatment certainly takes longer than 18 months. This very long treatment can affect the quality of life of MDR-TB patients. This study is to determine the correlation between the treatment phases with the quality of life of patients with Multidrug-resistant Tuberculosis in Dr. H. Abdul Moeloek Hospital Lampung Province. This study used 68 respondents who had been diagnosed with MDR-TB by pulmonary specialists. Primary data was taken using SF-36 questionnaire to measure the quality of life of MDR-TB patients, then secondary data based on the treatment phases using the medical record of the patient who had filled out the questionnaire. The data is processed and analyzed by the program in the computer. Data were tested by chi-square test and the results were obtained from 30 respondents in the initial treatment phases, 22 people (73.3%) quality of life was poor and 8 people had good quality of life (26.7%), while from 38 respondents at the continued treatment phases, as many as 12 people (31.6%) quality of life is bad and 26 people have good quality of life (68.4%). The result of bivariate analysis showed the variable had a correlation with p-value=0,001. There is a correlation between the treatment phases with the quality of life of patients with Multidrug-resistant Tuberculosis in RSUD Dr. H. Abdul Moeloek.
Hubungan Indeks Masa Tubuh pada Balita Stunting Terhadap Kadar Hemoglobin di Kecamatan Gunung Sugih Kabupaten Lampung Tengah Frigandra Syahputri; Khairun Nisa Berawi; Eca Cania
Medula Vol 10 No 2 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i2.60

Abstract

The prevalence of stunting in Gunung Sugih District, Lampung Tengah Regency, Lampung Province is high for stunting category in Indonesia. Nutritional status in stunting can be measured by body mass index according to age (BMI /A). Stunting has anemia as hemodynamic problems due to lack of iron (Fe) intake. The parameter which is used for measure anemia is hemoglobin. This study aims to determine the relationship between BMI in stunting children and hemoglobin levels as a marker of anemia. Observational analytic method with cross sectional approach was used in this study with 35 samples (cluster random sampling). Primary data are height, weight, body mass index (BMI) and hemoglobin (Hb) levels as measured by Hb Meter (Dr.Family®). Data analysis was performed by Pearson correlation test. Obtained a normal BMI of -0.51SD with a percentage of 94.3%. Hb levels with a mean of 10.4 g/dL and 57.1% of children had anemia. The results of the Pearson correlation test found that Ho was received with value of p=0.511 (p>0.05) and had a positive correlation (r=0.115). This study did not show a significant relationship between body mass index (BMI) of hemoglobin (Hb) levels as a marker of anemia in stunting infants in Gunung Sugih District, Central Lampung Regency.
Efek Anti-Mikrobial pada Ekstrak Cinnamomum verum (Kayu Manis) sebagai Terapi Adjuvant pada Malaria Falciparum Khairun Nisa; Fitria Putridewi Abidin
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.167

Abstract

Malaria is a major public health problem in the world, especially in Indonesia. The prevalence of malaria in Indonesia reaches 6 percent with 2000 deaths each year, most of which are caused by Plasmodium falciparum. Various treatment options for falciparum malaria have been developed, but due to various factors, one of which is the adherence of patients who are not monitored medication, increases the risk of resistance to current malaria therapy. Therefore, the researchers conducted further research on alternative malaria therapies. Cinnamomun verum or cinnamon is known to contain cinnamaldehyde compounds which have antimicrobial properties. The purpose of this study was to determine the anti-microbial effect of Cinnamomun verum (cinnamon) extract as an adjuvant therapy in falciparum malaria. This literature review article takes 25 case report articles, research articles, and literature reviews. The conclusion of this study is that the cinnamaldehyde compound in the extract of Cinnamomun verum has an antiparasitic effect which can inhibit the denaturation potential of amino acids, inhibits β-hematin formation and activity of the reductase enzyme on Plasmodium falciparum enoyl-ACP reductase. It is known that these four things have an important role in the pathogenesis of falciparum malaria.
Pengaruh Kebiasaan Merokok terhadap Fungsi Paru pada Pegawai Pria di Gedung Rektorat Universitas Lampung Khairun Nisa; Liana Sidharti; Muhammad Farid Adityo
JUKE Unila Vol 5, No 9 (2015)
Publisher : Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.058 KB)

Abstract

Salah satu faktor yang dapat mempercepat penurunan fungsi paru adalah merokok. Penurunan fungsi paru ditandai dengan penurunan nilai volume ekspirasi paksa satu detik (VEP1), penurunan kapasitas vital paksa (KVP) dan rasio VEP1/KVP. Tujuan penelitian adalah untuk mengetahui pengaruh lama merokok dan jumlah konsumsi harian terhadap rasio VEP1/KVP pada pegawai laki laki di Rektorat Universitas Lampung. Metode penelitian ini adalah penelitian eksperimental dengan desain penelitian cross sectional. Penelitian ini dilakukan di Rektorat Universitas Lampung pada bulan Desember 2014. Populasi yang digunakan dalam penelitian ini adalah pegawai laki-laki dengan rentang usia 25-50 tahun di Rektorat Universitas lampung. Sampel penelitian berjumlah 68 orang dengan teknik pengambilan sampel menggunakan consecutive sampling. Adapun analisis statistik yang digunakan pada penelitian ini adalah uji chi-square. Berdasarkan hasil analisis regresi logistik mulai dari pemilihan variabel ke analisis regresi logistik sampai model akhir, yang menjadi faktor dominan terhadap rasio VEP1/KVP adalah jumlah konsumsi harian rokok 1-10 batang dengan p=0,005. Simpulan. lama merokok dan jumlah konsumsi harian rokok berpengaruh terhadap rasio VEP1/KVP pegawai laki-laki usia 25-50 tahun di Rektorat Universitas Lampung. [JuKe Unila 2015; 5(9):38-42]
Perbandingan antara V02 Maks dan Daya Ledak Otot Atlet Pria Cabang Olahraga Renang dan Lan i Sprint pada Persiapan Pekan Olahraga Propinsi di Bandar Lampung Khairunnisa Berawi; M Masykur Berawi
JUKE Unila Vol 3, No 01 (2013)
Publisher : Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5863.208 KB)

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Pengaruh Pemberian Ekstrak Etanol Kulit Pisang Janten Terhadap Kadar HDL dan LDL Tikus Putih Jantan Galur Sprague Dawley Khairunnisa Berawi; CNA Qolbi
JUKE Unila Vol 3, No 02 (2013)
Publisher : Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (8130.629 KB)

Abstract

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Co-Authors Admi Syarif Agung, Leni Yulinda Kesuma Agus Wantoro Agustyas Tjiptaningrum Ahmad Arkan Ichsan Ahmad Arkan Ichsan Alicia Rahma, Cinta Alinta Ayuningtyas Alinta Amir, Anzela Angelica Philia Christy Anggraeni Janar Wulan anggraini janar wulan Angraini, Dwi Indria Anisa Adelia Annisa Adietya Pratama Annisa Fath Annisa Putri Perdani Apri Lyanda Arsistya Ayu Marella Asep Sukohar Assidiq, Hans Pratama Ayu Dinda Fatimah Azizah Nur Rahmah Azizah, Nailul Azizza, Zahra Qori Chicy WIdya Morfi CNA Qolbi Dea Okta Pabiola Dewi Nur Fiana Dewi Nur Fiana Dewi Nur Fiana Dian Isti Anggraini Dian Isti Angraini Dian Syafitri Dian Syafitri Dian Syafitri Diana Mayasari Dilangga, Pad Dinda Annisa Fitria Ditya Ananda Safira Diva Iole Humaira Dwita Oktaria Dyah Wulan Sumekar Rengganis Wardani Eca Cania Efrida Warganegara Emantis Rosa Ester Krisdayanti Exsa Hadibrata Fauzi Ahmad Muda Fauziyyah Nuur Al Azizah Feni Astiti Fitria Putridewi Abidin Fitria Saftarina Frigandra Syahputri Ghaitsa Lulua Giska Tri Putri Gozali, Achmad Haikal Nirfandi Haikal Shiddiq Hanif, Fauziah Happy, Terza Aflika Helmi Ismunandar Hendri Busman Heni Sulistiani Herdato, M. Junus Didiek Ilham Nugroho Ilham Nugroho Iswandi Darwis Jauzaa Faishal Ahmad Padmadisastra Khalisah Nurjihany Salsabila Kurnia Muludi Kurniawan, Ryanda Masri Kurniawaty, Evi Kusumajati, Pusparini Latief, Adhi Nugroho Leni Ervina, Leni Lesilolo, Caroline Virgine Putri Liana Sidharti M Masykur Berawi M. Irfan zaki Rici Maharani, Atifah Fadilah Marcellia, Selvi Marzon, Mafalda Maulana Irfan Hazairin Siregar Messah, Anse Diana Valentiene Muhammad Aditya, Muhammad Muhammad Aditya, Muhammad Aditya Muhammad Farid Adityo Muhammad Rifki Pratama Muhartono Muhartono Neema Putri Prameswari Nelly Yuana Nisa Karima Nisa Karima Nur Anggraini Nurul Islamy Oktafany, Oktafany Oktavia Ningtias, Nabila Perdami, Roro Rukmi Windi Pramesona, , Bayu Anggileo Puspaningrum, Dewi Ayu Putri Giani Purnamasari Qanita Arindia, Naifa Hana Rahma, Cinta Alicia Ramadhan, Yasmine Aulia Ramadhana Komala Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Ratu Nirmala Wahyunindita Redi Bintang Pratama Reni Zuraida Risti Graharti Riyan Wahyudo Roro Rukmi Windi Perdani, Roro Rukmi RR. Ella Evrita Hestiandari Salma Khairunnisa Samsul Bakri Sembiring, Rinawati Septiani, Linda Smith Imanuel Saputra Soemarwoto, Retno Ariza S. Sri Ratna Sulistiyanti Suci Nurhaliza Suharmanto Suharmanto Suharmanto Suryadi Islami Susianti Susianti Sutyarso Sutyarso Syahrani Alya Murfi Ta Larasati TA Larasati Tasya Khariena Akbar Theodora Agverianti Tsurayya Fathma Zahra Verizka, Talitha Warsito Warsito Warsono Warsono Wibowo, Gatra Hadimuti Winda Trijayanthi Utama, Winda Trijayanthi Wuryaningsih Dwi Sayekti Yoga, M. Agung Prasetya Adnyana Yolanda, Jennifer Ester Yulita Yulita Zefanya, Ezekial