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Pengaruh Pemberian Ekstrak Etanol Rimpang Lengkuas (Alpinia galanga) terhadap Gambaran Histopatologi Testis Mencit (Mus musculus L.) jantan yang Diinduksi Monosodium Glutamat Annisa Shafira Pramono; Muhartono; Rizki Hanriko; Eca Cania
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.43

Abstract

Monosodium Glutamate (MSG) may form free radicals that cause damages to the organs of the body, one of which is the male reproductive organs, i.e. testes. Galangal rhizome is one of the natural ingredients with antioxidant content that can neutralize free radicals. The purpose of this research was to determine the effect of ethanol extract of galangal rhizome on testicular histopathology of MSG-induced male mice. The design of this research was experimental research with 5 treatment groups, each group consisted of 5 mice (Mus musculus L.) DDY strain. Group K (-) was not treated; k (+) was provided with 4 mg/ grBB MSG; P1 was provided with 4 mg/ grBB MSG + 14 mg/ 20 grBB ethanol extract of galangal rhizome; P2 was provided with 4 mg/ grBB MSG + 28 mg/ 20 grBB ethanol extract of galangal rhizome; P3 was provided with 4 mg/ grBB MSG + 56 mg/ 20 grBB ethanol extract of galangal rhizome. Assessment used Johnsen score in group K(-) was 48,4, K(+) was 47,4, P1 was 47,4, P2 was 47,4, and P3 was 48. Kruskal-Wallis test result was p=0,085 (p>0,05). The conclusion was that ethanol extract of galangal rhizome did not effect significantly (p>0,05) on the testicular histopathology of monosodium glutamate-induced mice.
Hubungan Indeks Masa Tubuh pada Balita Stunting Terhadap Kadar Hemoglobin di Kecamatan Gunung Sugih Kabupaten Lampung Tengah Frigandra Syahputri; Khairun Nisa Berawi; Eca Cania
Medula Vol 10 No 2 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i2.60

Abstract

The prevalence of stunting in Gunung Sugih District, Lampung Tengah Regency, Lampung Province is high for stunting category in Indonesia. Nutritional status in stunting can be measured by body mass index according to age (BMI /A). Stunting has anemia as hemodynamic problems due to lack of iron (Fe) intake. The parameter which is used for measure anemia is hemoglobin. This study aims to determine the relationship between BMI in stunting children and hemoglobin levels as a marker of anemia. Observational analytic method with cross sectional approach was used in this study with 35 samples (cluster random sampling). Primary data are height, weight, body mass index (BMI) and hemoglobin (Hb) levels as measured by Hb Meter (Dr.Family®). Data analysis was performed by Pearson correlation test. Obtained a normal BMI of -0.51SD with a percentage of 94.3%. Hb levels with a mean of 10.4 g/dL and 57.1% of children had anemia. The results of the Pearson correlation test found that Ho was received with value of p=0.511 (p>0.05) and had a positive correlation (r=0.115). This study did not show a significant relationship between body mass index (BMI) of hemoglobin (Hb) levels as a marker of anemia in stunting infants in Gunung Sugih District, Central Lampung Regency.
Co-Authors Annisa Shafira Pramono Frigandra Syahputri Khairun Nisa Muhartono Rizki Hanriko