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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Majalah Obstetri dan Ginekologi Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Prosiding Seminar Nasional Program Pengabdian Masyarakat
Dhiya An, Alfun
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Economics, Econometrics & Finance Health Professions Medicine & Pharmacology Public Health Social Sciences

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Expression Level of Cyclin-D1 between Endometriomas and Ovarian Carcinomes Dhiya An, Alfun; Supriyatiningsih, Supriyatiningsih
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1: January 2021
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.7212

Abstract

Endometrioma on the ovaries is a benign gynecological disorder that is often found in women of reproductive age. The approach was made to the malignant transformation through the study of cyclin-D1 expression. This research aim to analyze differences in the level of Cyclin-D1 expression in ovarian endometriosis and ovarian carcinoma associated with the pathogenesis of endometrioma and ovarian carcinoma. Analytical observational study with cross sectional approach to cyclin-D1 expression between endometrioma and ovarian carcinoma with good and bad differentiation. The research subjects were 20 cases of endometrioma, each of the 20 cases of ovarian carcinoma were well and poorly differentiated. Statistical analysis using the ANOVA test on the level of cyclin-D1 expression between groups. The mean cyclin-D1 expression in endometrioma was 67.25. The mean of well-differentiated ovarian carcinoma was 132.41. The mean of poorly differentiated ovarian carcinoma was 128.83. Anova test resulted in a significant difference between the expression of cyclin-D1 endometrioma and ovarian carcinoma with good and bad differences (p = 0.00 0.05). There is a significant difference between endometrioma and ovarian carcinoma with good and bad differentiation. Endometrioma cyclin-D1 expression was lower than ovarian carcinoma with good and bad differentiation.
Sensitivity and Specificity of Modified Early Obstetric Warning Score (MEOWS) and Maternal Early Warning Criteria (MEWC) for Maternal Morbidity: A Retrospective Cohort Study in Pregnant Women with COVID-19 Cahyani, Dinda Desti; Priyanto, Heru; Dhiya An, Alfun; Supriyatiningsih
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 4 October 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i4.2108

Abstract

Objective: To measure the comparative sensitivity, specificity, and predictive value of MEOWS and MEWC in predicting morbidity in pregnant patients infected with COVID-19. This research can be one of the screenings used to determine the level of care for pregnant patients with COVID-19. Methods: The retrospective cohort technique was used to examine the 89 pregnant women with COVID-19 who were admitted to the Bantul Regional General Hospital between January and December 2021. Data analysis used the ROC curve to compare sensitivity, specificity, and predictive value. Results: MEWC is better than MEOWS in predicting the morbidity of pregnant patients with COVID-19 infection. This is because MEWC has a better sensitivity (78,3%) and PPV value (78%) than MEOWS, even though it has a lower specificity value (81,8%) and NPV value (82%). The specificity value of MEWC (81.8%), when compared to MEOWS (97.1%), does have a lower specificity value. The results of MEOWS and MEWC data analysis using ROC produce an area under the curve for MEOWS of 74,9% while for MEWC of 80%. Discussion: MEWC has a better sensitivity indicating that patients who do not trigger MEWC criteria will have a low risk of experiencing maternal morbidity. Screening tools will prioritize the sensitivity value compared to the specificity value of the instrument used. A screening tool will have a lower positive predictive value if the study population has a lower prevalence of morbidity. Based on the comparison of the predictive value, sensitivity, and specificity of the MEWC and MEOWS instruments, it can be concluded that MEWC is associated with maternal morbidity with a higher sensitivity than MEOWS, although it has a lower specificity. High sensitivity values will result in screening tools with consistent results. The ROC curve can also show that MEWC has a higher sensitivity value by looking at the Y-coordinate, which is higher than the Y-coordinate of MEOWS. MEWC has a better Receiver Operator Curve (ROC) intersection point than MEOWS, where the MEWC intersection point has the furthest point on the upper left of the ROC diagonal line. Conclusion: MEWC has a higher sensitivity compared to MEOWS, even though it has a lower specificity. High sensitivity values will produce screening tools with consistent results. Keywords: MEWC, maternal early warning system, maternal morbidity, MEOWS
Optimalisai Kesehatan Ibu Hamil Beresiko Tinggi dan Upaya Preventif terhadap Kejadian Stunting di Desa Jlegongan Fauzan, Muhammad; Jannah, Arrinda Miftachul; Wahyuningsih, Alifia Arienda; Zuhdi, Hilal; Rahman, Muhammad Fadhila; Prayoga, Aqbil Fajar; Az Zahra, Taqiyyatuts Tsabitah; Adzqiya, Fatan; Pribadi, Fachsheila H.; Nurwulandari, Vionita; Dhiya An, Alfun
Prosiding Seminar Nasional Program Pengabdian Masyarakat Vol. 8 No. 1 (2025): Rekonstruksi Pendidikan di Indonesia
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ppm.81.1279

Abstract

The incidence of stunting is caused by various things, including maternal factors during pregnancy, nutritional intake during toddlerhood, infection, environmental factors and parenting. Prevention can be done early, namely when the baby is in the womb (when the mother is pregnant) must get balanced nutrition. In the Jlegongan Padukuhan area, there are several pregnant women experiencing high-risk pregnancies. In addition, pregnant women in the Jlegongan Padukuhan area are less familiar with the nutritional needs of pregnant women, as well as the consequences that occur if nutritional needs during pregnancy are not met properly. The purpose of this community service project is to increase the knowledge and regeneration of posyandu cadres about the importance of proper nutrition during pregnancy as an early effort to prevent stunting. The Real Work Lecture activity method uses a participatory approach with a qualitative descriptive technique that aims to understand the conditions and health problems of pregnant women in depth consisting of observation, planning, practice and counseling. The activities carried out are Counseling on Stunting Prevention, DASHAT (Healthy Kitchen to Overcome Stunting), Counseling on Reproductive Health, Family Planning, and Productive Age Women, and Anthropometric Measurements for Toddlers. The results of the Nyara Work Lecture obtained an increase in good knowledge about stunting and the importance of nutrition during pregnancy by 90% compared to the knowledge before the majority of activities carried out by 50%. Activities are expected to be carried out and evaluated regularly as an effort to prevent stunting.
Global research trends in partograph: A bibliometric analysis Dhiya An, Alfun; Maulidya, Asri Nur; Ulfa, Maria
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.152-163

Abstract

HIGHLIGHTS This study highlights growing global attention on the partograph as a part of labor monitoring. Partograph use remains inconsistent and affects clinical decision-making and management of labor. Future studies should focus on digital monitoring and policy effectiveness in intrapartum care as a part of enhancing maternal and neonatal outcomes.   ABSTRACT Objective: The present study aimed to clarify the emerging patterns in partograph utilization, its development, and its impact on clinical practice. Materials and Methods: A bibliometric analysis was conducted using Scopus as the primary database. Articles were retrieved using the keywords “Partograph” or “Partogram” and analyzed using two strategies: performance analysis (Scopus “analyze” function) and network analysis (VOSviewer and NVivo). Results: Five hundred and thirteen articles published between 1965 and 2025 were analyzed. Performance analysis revealed that the most cited studies focused on labor management, labor progression, and maternal and neonatal health outcomes. The leading publishing countries included Ethiopia, the United States, the United Kingdom, India, and South Africa. Network analysis identified strong connections between partograph research and healthcare quality, personnel delivery, and facilities. Research trends evolved from early studies on spontaneous delivery, dystocia, and maternal mortality to more recent investigations into partograph utilization as a healthcare service quality improvement tool. Pearson correlation analysis showed strong associations between partograph use and birth outcomes (0.81), mortality (0.78), and healthcare workers’ perspectives (0.76). Conclusion: Research on partograph utilization continues to expand, focusing on labor monitoring and its impact on maternal and neonatal outcomes. Recently, studies have shifted toward labor-management quality, healthcare service improvement, and patient safety. However, certain areas remain underexplored, presenting opportunities for further research.
Co-Authors Adzqiya, Fatan Az Zahra, Taqiyyatuts Tsabitah Cahyani, Dinda Desti Heru Priyanto Jannah, Arrinda Miftachul Maria Ulfa Maulidya, Asri Nur Muhammad fauzan Nurwulandari, Vionita Prayoga, Aqbil Fajar Pribadi, Fachsheila H. Rahman, Muhammad Fadhila Supriyatiningsih Supriyatiningsih, Supriyatiningsih Wahyuningsih, Alifia Arienda Zuhdi, Hilal