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Expression Level of Cyclin-D1 between Endometriomas and Ovarian Carcinomes Dhiya An, Alfun; Supriyatiningsih, Supriyatiningsih
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1: January 2021
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.7212

Abstract

Endometrioma on the ovaries is a benign gynecological disorder that is often found in women of reproductive age. The approach was made to the malignant transformation through the study of cyclin-D1 expression. This research aim to analyze differences in the level of Cyclin-D1 expression in ovarian endometriosis and ovarian carcinoma associated with the pathogenesis of endometrioma and ovarian carcinoma. Analytical observational study with cross sectional approach to cyclin-D1 expression between endometrioma and ovarian carcinoma with good and bad differentiation. The research subjects were 20 cases of endometrioma, each of the 20 cases of ovarian carcinoma were well and poorly differentiated. Statistical analysis using the ANOVA test on the level of cyclin-D1 expression between groups. The mean cyclin-D1 expression in endometrioma was 67.25. The mean of well-differentiated ovarian carcinoma was 132.41. The mean of poorly differentiated ovarian carcinoma was 128.83. Anova test resulted in a significant difference between the expression of cyclin-D1 endometrioma and ovarian carcinoma with good and bad differences (p = 0.00 0.05). There is a significant difference between endometrioma and ovarian carcinoma with good and bad differentiation. Endometrioma cyclin-D1 expression was lower than ovarian carcinoma with good and bad differentiation.
Willingness to Pay for Maternity Waiting Homes in Rural Indonesia Dewi, Arlina; Supriyatiningsih, Supriyatiningsih; Sundari, Sri; Sugiyo, Dianita; Lellee, Ralph. J.
JMMR (Jurnal Medicoeticolegal dan Manajemen Rumah Sakit) Vol 9, No 2 (2020): August
Publisher : Universitas Muhammadiyah Yogyakarta in Clollaboration with ADMMIRASI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jmmr.92122

Abstract

Distance to a health care facility has long been discussed as a key barrier to maternal health care utilization in rural areas.  Maternity Waiting Homes (MWHs) has been proved to the reductions of maternal mortality. The objective of this study was to investigate the pregnant women’s Willingness to Pay (WTP)  toward the maternity waiting homes (MWHs).  The cross-sectional study was conducted in two rural areas in South Sulawesi, Indonesia. The data were collected through survey which was distributed to pregnant women and their families. A total of fifty-one pregnant women and forty-nine families participated in the study as two groups of respondents. For the results of this study, there were 66.7% of pregnant women agreed if they should stay at MWHs. For a group of pregnant women, the amount of WTP which was capable to be paid was 100.000 IDR in a month. Moreover, for a group of family, the amount of WTP which they could pay for staying at MWH was 200.000 IDR in a month. The pregnant women’s acceptance to stay in MWH is good, but their willingness to pay is still very low.
Pentingnya Pengetahuan Pemeriksaan Payudara Sendiri sebagai Deteksi Dini Kanker Payudara Supriyatiningsih, Supriyatiningsih; Rachmanio, Nicko; Kurniawan, Muhammad
Berdikari: Jurnal Inovasi dan Penerapan Ipteks Vol 10, No 1 (2022): February
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/berdikari.v10i1.13594

Abstract

Breast cancer is included in the five types of cancer that result in death. The reason is the delay in early detection so that survivors of this type of cancer are generally detected at an advanced stage. The community service entitled "PKM Knowledge and Early Detection of Breast Cancer in Women of Reproductive Age" aims to provide knowledge about the importance of breast self-examination (BSE) as an effort to detect breast cancer early. The method used is through online seminars via Zoom Meetings to 20 employees and their families at the Obstetrics and Gynecology Clinic, Muhammadiyah Asri Medical Center Hospital, Yogyakarta. The material provided was in the form of knowledge about women's health, breast cancer and its treatment, and training on BSE, which was preceded by a pretest to measure participants' knowledge before the seminar and a posttest at the end of the activity after receiving the seminar. The results of the pretest and posttest were analyzed using the Wilcoxon Signed-Rank test method. The results of the pretest showed that 17 participants (85.0%) had sufficient knowledge about BSE and 2 participants (10.0%) had less knowledge. The posttest results showed that all participants (100.0%) had knowledge in the good category about BSE. The test results showed a significance value of 0.001 (p 0.05), which means that there was a significant increase in participants' knowledge about BSE as early detection of breast cancer before and after the seminar.
Newborn Weight and Second-Hand Smoking in Utero Exposure: A Case in A Low-Middle Income Country Sugiyo, Dianita; Supriyatiningsih, Supriyatiningsih; Sutantri, Sutantri; Sutrisno, Resti Yulianti; Indriastuti, Nur Azizah; Aditjondro, Enrico; Yuswatiningsih, Endang; Helmi, M; Wandasari, Noven Tri; Tanjung, Afriansyah; Afghani, Soewardiman Al; Satria, Faudyan Eka; Hapsari, Saphira Hanan; Samsudin, Mohammad Agus; Rachmawati, Riska Putri
Jurnal Keperawatan Soedirman Vol 18 No 3 (2023): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2023.18.3.6600

Abstract

Smoking exposure among pregnant women is correlated with the risk of low birth weight. The policy factors are believed to contribute to the rate or prevalence of smoking activities. This study aims to simultaneously portray the incidence of low-birth-weight newborns correlated with smoking exposure. The samples were 160 respondents, with 57 and 103 respondents in Hospital A and G respectively. A mixed-method analysis was utilized by combining a retrospective approach to identify the key findings and be equipped with a narrative analysis of the socio-demographic - law enforcement process. The Spearman correlation analysis was used for investigating correlation among variables. Spearman correlation test smoking exposure per day in minutes (rho= -0.595, p<0.001) and the number of smokers (rho= -0.621, p<0.001) for Hospital A, and smoking exposure per day in minutes (rho= -0.681, p<0.001) and the number of smokers (rho= -0.613, p<0.001) for Hospital G. It implied a strong correlation of inverse relationship among those variables. Smoke-free law enforcement is a key point to address, aiming at vulnerable group protection, including pregnant mothers and babies. The local government should consider the effects affected by smoking behavior in the community.