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PENGARUH EKSTRAK KUNYIT PUTIH TERHADAP HISTOPATOLOGI GINJAL PADA TIKUS JANTAN DENGAN MODEL NEPHROPATHY DIABETICUM Aulia, Rumi; Damanik, Marco Frans Hernandes; Tandanu, Erny; Ferdinand, Sahna
(Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Vol 6, No 1 (2021): JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat)
Publisher : Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37887/jimkesmas.v6i1.16375

Abstract

Abstrak DiabetesXmellitusX (DM) XmerupakanXsuatuXpenyakitXkronisXyangXditandaiXoleh peningkatan kadar guladarah dalam tubuh akibatXgangguanXpadaXsekresiXinsulin, XhormonXinsulinXyangXtidakXbekerja sebagaimanaXmestinyaXatauXkeduanya. XKondisi hiperglikemia yang berlangsung kronis akan menimbulkankomplikasi pada berbagai organ salah satunya adalah organ ginjal. PenelitianXiniXbertujuanXuntuk mengetahuipengaruhXpemberianXekstrak kunyit putih (Curcuma zedoaria) terhadap gambaran histopatologi ginjal padatikus jantan dengan model nephropathy diabeticum. Rancangan penelitian ekperimental ini bersifat OneGroupPretest PostTest Design menggunakan sampel 30 ekor tikus jantan (Rattus norvegicus L.) galur Wistar,dimana tikus diinduksiXdengan penyuntikkan aloksanXdenganXdosis 180mg/KgBBXsecara intraperitoneal.Kemudian tikus dibagi menjadi 6 kelompokXyaitu 1 kelompok normal dan 5 kelompok tikus modelhiperglikemia yang diberi ekstrak kunyit putih denganXdosis 250, 500 dan 750mg/KgBB selama 14 hari,kelompok kontrol positif (glibenclamid 0,45mg/KgBB) dan kelompok kontrol negatif (tikus model hiperglikemiatanpa perlakuan). PadaXhariXke-14 tikus dikorbankan dan diambil darah untuk pemeriksaan kadar gula darahdan ginjalnya untuk pemeriksaanXhistologi denganXpewarnaan menggunakan HematoksilinEosin (H-E). HasilpenelitianXmenunjukanXbahwaXpemberianXekstrakXkunyit putih (Curcuma zedoaria) memiliki aktivitasnefroprotektif.KataXKunciX: Diabetes Melitus, Kunyit Putih, Nefroprotektif
Hospital Preparedness and Resilience in Public Health Emergencies at Royal Prima Medan Hospital Aulia, Rumi; Ginting, Chrismis Novalinda; Chiuman, Linda
Eduvest - Journal of Universal Studies Vol. 5 No. 1 (2025): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i1.1787

Abstract

Hospitals have a very important role in public health, because hospitals are places where people can get maximum health services to support the health of these patients. With the importance of the role of hospitals for the community, it is necessary to have preparedness and resilience on the part of the hospital to always be ready to receive emergencies that come from the community, such as when a disaster occurs where the role of the hospital is very important in helping victims affected by disasters. . The aim of this research is to determine the preparedness and resilience of hospitals in public health emergencies at RSU Royal Prima Medan. This type of research is quantitative research with a cross sectional approach. The population in this study was all medical and non-medical employees at RSU Royal Prima Medan, totaling 822. The sampling method used in this research was systematic sampling. The sampling technique in this research used Proportional Random Sampling so that the number of samples in this research was 134 samples. Data analysis in this study used univariate analysis. The results showed that the majority of respondents in this study were aged 36-45 years, 73 people, the majority were female, 91 people, the majority had worked < 5 years, 74 people and the majority worked as nurses, 50 people. The preparedness of RSU Royal Prima Medan in facing public health emergencies is good, the resilience of RSU Royal Prima Medan in facing public health emergencies is good.