Syahrom, Ardiyansyah
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Simulasi Prediksi Tekanan Kontak pada Permukaan Acetabular Cup dengan Aplikasi Permukaan Bertekstur pada Total Hip Arthroplasty Ammarullah, Muhammad Imam; Saad, Amir Putra Md; Syahrom, Ardiyansyah; Basri, Hasan; Jamari, Jamari
Jurnal Rekayasa Mesin Vol 15, No 3 (2020): Volume 15, Nomor 3, Desember 2020
Publisher : Jurusan Teknik Mesin - Politeknik Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32497/jrm.v15i3.1993

Abstract

Kajian ini bertujuan untuk menganalisa tekanan kontak pada permukaan acetabular cup dengan dan tanpa paplikasi permukaan bertekstur. Kontribusi utama dari studi ini adalah mempelajari efek penambahan dimple terhadap tekanan kontak yang berkorelasi terhadap keausan yang terjadi. Pendekatan dengan menggunakan perangkat lunak dilakukan dengan melakukan pemuatan fisiologis sambungan tulang pinggul secara 3D dalam kondisi berjalan normal. Analisa tekanan kontak dilakukan secara kontak langsung dan deskritasi elemen hingga dengan metode dua kutub dilakukan untuk memberikan hasil tekanan kontak yang akurat. Hasil menunjukkan bahwa model total hip arthroplasty dengan penambahan dimple dapat mengurangi tekanan kontak untuk seluruh fase dalam satu siklus penuh yang menjelaskan bahwa penambahan dimple pada permukaan acetabular cup di total hip artroplasti dapat mengurangi tekanan kontak dan mengurangi keausan.
The compressive strength and static biodegradation rate of chitosan-gelatin limestone-based carbonate hydroxyapatite composite scaffold Rianti, Devi; Purnamasari, Alqomariyah Eka; Putri, Rifayinqa Ruyani; Salsabilla, Noor Zain; Faradillah; Munadziroh, Elly; Agustantina, Titien Hary; Meizarini, Asti; Yuliati, Anita; Syahrom, Ardiyansyah
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p160-165

Abstract

Background: One of the main components in tissue engineering is the scaffold, which may serve as a medium to support cell and tissue growth. Scaffolds must have good compressive strength and controlled biodegradability to show biological activities while treating bone defects. This study uses Chitosan-gelatin (C–G) with good flexibility and elasticity and high-strength carbonate hydroxyapatite (CHA), which may be the ideal scaffold for tissue engineering. Purpose: To analyze the compressive strength and static biodegradation rate within various ratios of C–G and CHA (C–G:CHA) scaffold as a requirement for bone tissue engineering. Methods: The scaffold is synthesized from C–G:CHA with three ratio variations, which are 40:60, 30:70, and 20:80 (weight for weight [w/w]), made with a freeze-drying method. The compressive strengths are then tested. The biodegradation rate is tested by soaking the scaffold in simulated body fluid for 1, 3, 7, 14, and 21 days. Data are analyzed with a one-way ANOVA parametric test. Results: The compressive strength of each ratio of C–G:CHA scaffold 40:60 (w/w), 30:70 (w/w), and 20:80 (w/w), consecutively, are 4.2 Megapascals (MPa), 3.3 MPa, 2.2 MPa, and there are no significant differences with the p= 0.069 (p>0.05). The static biodegradation percentage after 21 days on each ratio variation of C–G:CHA scaffold 40:60 (w/w), 30:70 (w/w), and 20:80 (w/w) is 25.98%, 24.67%, and 20.64%. One-way ANOVA Welch test shows the result of the p-value as p<0.05. Conclusion: The compressive strength and static biodegradation of the C–G:CHA scaffold with ratio variations of 40:60 (w/w), 30:70 (w/w), and 20:80(w/w) fulfilled the requirements as a scaffold for bone tissue engineering.