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All Journal JKG (Jurnal Keperawatan Global) Folia Medica Indonesiana
Othman, Zulhabri
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Nursing

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Effectiveness Of Psychoeducation And Assertive Training (PEAT) Combined For Improving Medication Adherence In Patients With Schizophrenia Insiyah, Insiyah; Abdul Karim, Sairah; Othman, Zulhabri
JKG (JURNAL KEPERAWATAN GLOBAL) (JKG) Jurnal Keperawatan Global Volume 9 Number 1 Year 2024
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkg.v9i1.914

Abstract

Background: Non-adherence behaviors have a variety of causes, from suffering negative drug side effects to having scepticism regarding the effectiveness of recommended treatments. Recognising these complex relationships is essential to creating strategies that effectively manage the psychosocial as well as medical components of schizophrenia. The purpose of this study is to investigate how a combination of psychoeducation and assertive training can improve medication adherence in people with schizophrenia. Methods: A pretest-posttest quasi-experiment design was employed in this study as part of a quantitative research technique. Demographics and the Morisky Medication Adherence Questionnaire were used in conjunction with observation to collect data. Based on room-based simple random sampling, 80 patients with schizophrenia who met the inclusion criteria were split into two groups. Of these, 38 patients in the intervention group and 36 responders in the control group finished the study. This study made use of the five-stage Psychoeducation and Assertive Training (PEAT) module. Results: A combination of psychoeducation and assertiveness training (PEAT) was found to have an effect on medication adherence in this study. Following PEAT, patients with schizophrenia had a mean medication adherence of 5.92±1.29. The statistical test findings showed that the mean medication adherence of schizophrenic patients receiving PEAT differed significantly (p value <0x7E>0.001) from those who did not. Conclusion: Studies show that putting more of an emphasis on PEAT can help hospitals treat patients with schizophrenia more consistently by helping them take their medications as prescribed. Additionally, patients with schizophrenia should have a treatment plan that includes PEAT.
Analysis of Spatial Working Memory Using the Y-Maze on Rodents Treated with High-Calorie Diet and Moderate-Intensity Exercise Melbiarta, Rezy Ramawan; Kalanjati, Viskasari P.; Herawati, Lilik; Salim, Yusuf; Othman, Zulhabri
Folia Medica Indonesiana Vol. 59, No. 1
Publisher : Folia Medica Indonesiana

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Highlights: • This article reports the use of the Y-maze as a simple yet effective method to measure spatial working memory in mice. • The Y-maze method can be used safely without exposing the animals to additional stressors, as evidenced by the absence of mortality following the test. Abstract: Spatial working memory (SWM) in humans and animal models with impaired cognitive functions has been analyzed through a number of methods. However, this is still understudied in animal models treated with a high-calorie diet (HCD) and moderate-intensity exercise (MIE). The Y-maze was utilized as the assessment method in this study. A 40 x 9 x 9 cm3 Y-maze was employed to observe the animal models' spontaneous alternation (SA) as the representation of their SWM. This was done by calculating the total alternation percentage divided by total entry minus two. A total of 17 female Mus musculus mice aged 8 weeks were tested in the Y-maze to investigate their SWM using SA calculations. Each mouse was analyzed for eight minutes and recorded in a dark and quiet room to minimize bias due to environmental noise and lighting. Comparing the treatment group's (HCD+MIE) SA to the control group's SA revealed no statistically significant difference (p=0.451). Seven mice in the treatment group performed similarly to the mice in the control group in the Y-maze test, with no significant difference in their ability to complete the task. The mice in the treatment group exhibited no motor impairment, as indicated by complete movements of all their extremities while exploring the Y-maze within the allotted time. In conclusion, the Y-maze can be used as a reliable method to analyze SWM in overweight/obese Mus musculus animal models treated with moderate-intensity physical exercise.
High Calorie Diet with a Combination of Intermittent Restriction Affects the Reproductive Cycle and The Uterine Weight of Mice (Mus Musculus) Kumalasari, Anggraeni Dyah; Herawati, Lilik; Argarini, Raden; Lukitasari, Lina; Othman, Zulhabri; Ningrum, Astika Gita
Folia Medica Indonesiana Vol. 57, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

Highlight: • High-calorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice were analyzed. • Calories balance impact for female reproductive health. Abstract : Balanced calories affected for body health and daily activities. Lose of energy can disturb the health and daily activities, while over calorie for diets also causes disorders such as metabolic. When there are excess calories in the body will be involved. It can be an obesity risk, diabetes mellitus, fertility disorder, cancer, and cardiovascular disease. Furthermore, in women there can be an increase in menstrual disorders and fertility disorder risk (Silvestris et al., 2018). This study aims to analyze highcalorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice. Experimental laboratory is a mouse (mus musculus) female's balb/c as object population. Sampling techniques using probability sampling with simple random sampling type. The study results on fisher's exact test gave a result of p > 0.05 so there was no significant difference between control group, high calorie diet group, and high calorie diet with interval restrictions group on the results of vaginal swabs /post-treatment reproductive cycle. The study outcome on robust tests between control, high calorie diet, and high calorie diet with interval restrictions groups. Obtained results (p < 0.05) that mean there are some significant discrepancies in the weight of uterine organ between groups. Calories balance in the body can impact female reproductive health.
Co-Authors Abdul Karim, Sairah HERAWATI, LILIK Insiyah Insiyah Kumalasari, Anggraeni Dyah Lukitasari, Lina Melbiarta, Rezy Ramawan Ningrum, Astika Gita Raden Argarini Salim, Yusuf Viskasari P. Kalanjati