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All Journal International Journal of Public Health Science (IJPHS) Majalah Kedokteran Bandung Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Medical Journal of Indonesia Folia Medica Indonesiana Jurnal NERS Biomedika The Indonesian Journal of Public Health Buletin Farmatera Jurnal Respirasi (JR) Journal Orthopaedi and Traumatology Surabaya (JOINTS) Majalah Biomorfologi (Biomorphology Journal) AKSONA Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing)

Viskasari P. Kalanjati

Departemen Anatomi Dan Histologi, Fakultas Kedokteran Universitas Airlangga

Author-ID : 3484462

Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Other

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PENGARUH EKSTRAK BAYAM MERAH (AMARANTHUS GANGETICUS) TERHADAP MORFOLOGI STRATUM HIPOKAMPUS MODEL ANAK MENCIT PASCASAPIH INDUK YANG TERPAPAR TIMBAL SELAMA MASA KEHAMILAN Kalanjati, Viskasari; Pratiwi, Made Pury; Syakdiyah, Noer Halimatus; Widiasi, Etha Dini; Anggraeni, Mayang Rizki; Pratiwi, Intan Anggun; Argarini, Raden
Majalah Kedokteran Bandung Vol 46, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1418.333 KB)

Kandungan antioksidan ekstrak bayam merah (Amaranthus gangeticus) diduga dapat melawan efek toksik timbal asetat pada sistem saraf pusat. Penelitian ini bertujuan untuk mengamati pengaruh pemberian ekstrak bayam merah terhadap morfologi hipokampus model anak mencit (Mus musculus) pascasapih yang induknya terpapar timbal asetat per oral selama masa kehamilan. Penelitian dilakukan di Laboratorium Hewan Coba Fakultas Kedokteran, Universitas Airlangga (FKUA) pada bulan April?Juni 2013. Dua puluh tujuh ekor anak mencit pascasapih dibagi dalam 3 kelompok: M0 (sodium carboxymethyl cellulose atau CMC Na 0,5%), M1 (CMC Na 0,5%+timbal asetat 1,16 mg/10 g BB/hari) dan M2 (CMC Na 0,5%+timbal asetat 1,16 mg/10 g BB/hari+ekstrak bayam merah 382,2 mg/10 g BB/hari). Sediaan otak diambil untuk dibuat preparat histologi dengan pewarnaan hematoxylin-eosin (HE). Lebar stratum granulare girus dentatus (GD), stratum oriens-piramidale (SOP) CA1, CA2, dan CA3 dianalisis dengan analysis of variance (ANOVA) dan least significant different (p<0,05). SOP CA1 dan CA2 pada kelompok M2 lebih lebar dibandingkan dengan kelompok M1 (p<0,05). SOP CA1 kelompok M2 lebih lebar pula bila dibandingkan dengan M0 (p=0,001). Lebar SG dari GD dan SOP CA3 kelompok M2 menunjukkan nilai yang lebih tinggi (p>0,05). Simpulan, pemberian ekstrak bayam merah dapat mengurangi efek negatif timbal asetat yang merusak struktur hipokampus model anak mencit pascasapih yang induknya terpapar timbal selama kehamilan. Kata kunci: Bayam merah, hipokampus, timbal asetatEffect of Red Spinach (Amaranthus gangeticus) Extract on Hippocampus Morphology of Post-Weaning Mice Infant Model from Lead-Acetate Exposed Pregnant Mice Antioxidants in red spinach (Amaranthus gangeticus) extract are proposed to combat the toxicity of lead acetate in the central nervous system. The effect of red spinach extract to the morphology of post weaning mouse hippocampus model (Mus musculus) in pregnant mice that received oral lead acetate during pregnancy was analyzed. Twenty seven post-weaning mice offsprings were grouped into 3 groups: M0 (sodium carboxymethyl cellulose or CMC Na 0.5%), M1 (CMC Na 0.5%+lead acetate 1.16 mg/10 g of body weight/day) and M2 (CMC Na 0.5%+lead acetate 1.16 mg/10 g of body weight/day+red spinach extract 382.2 mg/10 g of body weight/day). Brains were histologically processed and stained with hematoxylin-eosin (HE). Width of stratum granulare (SG) of the dentate gyrus (GD) and each of stratum oriens-pyramidale (SOP) of CA1, CA2, CA3 from each mouse hippocampus were obtained and analyzed statistically using analysis of variance (ANOVA) and least significant difference (LSD) (p<0.05). The CA1 and CA2 SOPs in M2 were significantly wider compared to those of M1 (p<0.05). Meanwhile, the SOP of CA1 in M2 was significantly wider compared to that of M0 (p=0.001). The SG width of GD and the CA3 SOP in M2 were wider than those of M0 and M1 (p>0.05). In conclusion, red spinach extract might dampen the adverse effects of oral lead acetate in post-weaning mouse hippocampus model from pregnant mice orally exposed to lead acetate during pregnancy. Key words: Hippocampus, lead acetate, red spinach DOI: 10.15395/mkb.v46n3.116

Cardiovascular disease risk factors and anthropometry features among seemingly healthy young adults Viskasari P. Kalanjati; Rury T. Oktariza; Bambang E. Suwito; Krisnawan A. Pradana; Dzanuar Rahmawan; Abdurachman Abdurachman
International Journal of Public Health Science (IJPHS) Vol 10, No 1: March 2021
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v10i1.20554

We explored association between the levels of total cholesterol (TC) and uric acid (UA) to the middle upper arm circumference (MUAC), waist circumference (WC) and hip circumference (HC) amongst seemingly healthy university students in Kediri, Indonesia aged 17-23 years (n=150); no history of major previous diseases were found (i.e. metabolic syndrome). TC and UA measured from the capillary blood; standardised anthropometry measurements were done by trained medical doctors. Correlation, linear regression, independent t-test or Mann-Whitney analysis were performed with the level of significance of p<0.05. We found higher TC (p=0.053), UA (p<0.001), MUAC (p=0.009), HC (p=0.865) and WC (p=0.001) among males than among females. TC was significantly correlated to the UA with prevalence of hypercholesterolemia of 46.7% and hyperuricemia of 30% of all participants. All anthropometry was significantly correlated to the TC and UA among males (p<0.001); TC and UA were strongly corresponded to all anthropometry parameters among males. Hypercholesterolemia and hyperuricemia could be found amongst the seemingly healthy young adults in Indonesia; among males these are strongly correlated to the higher MUAC, WC and HC. Daily physical activity and proper healthy diet might help to decrease these cardiovascular disease risk factors.

PENGARUH SHIELDING ALUMINIUM FOIL TERHADAP PERUBAHAN KETEBALAN LAPISAN EPITEL KORNEA AKIBAT PAPARAN RADIASI GELOMBANG ELEKTROMAGNETIK PADA TIKUS WISTAR JANTAN Dion Krismashogi Dharmawan; Viskasari P Kalanjati; Abdurachman Abdurachman
JURNAL KEDOKTERAN DAN KESEHATAN Vol 7, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V7I2.11100

Ponsel telah diketahui memancarkan radiasi gelombang elektromagnetik (RGEM) yang digunakan sebagai media dalam telekomunikasi. Dampak buruk akibat paparan RGEM dapat terjadi pada lapisan epitel kornea mata yang secara anatomis terletak pada bagian anterior. Kami melakukan penelitian potensi aluminium foil (AF) sebagai perisai terhadap RGEM yang diukur dengan membandingkan ketebalan lapisan epitel kornea mata tikus kelompok kontrol dan perlakuan. Masing-masing tikus dimasukkan ke masing-masing kandang paparan secara terpisah. Sumber paparan RGEM berupa ponsel GSM 2100 (Taiwan) dengan SAR 0,84 – 1,86 W/kg yang tersambung wifi yang diletakkan di bagian bawah setiap kandang paparan tikus dengan paparan 4 jam /hari. Sejumlah 32 tikus dengan usia 2-3 bulan diacak dan dibagi menjadi 4 kelompok. Kelompok kontrol tanpa paparan RGEM terbagi menjadi K1 (tanpa pemberian AF) dan K2 (dengan pemberian AF). Sedangkan kelompok perlakuan yang diberi paparan RGEM terbagi menjadi P1 (tanpa pemberian AF) dan P2 (dengan pemberian AF). Hasil yang didapatkan bahwa kelompok P1 memiliki ketebalan lapisan epitel kornea paling tipis dibandingkan kelompok lainnya, namun secara statistik tidak signifikan (uji Kruskal Wallis; p value 0,147). Dari penelitian ini dapat disimpulkan bahwa, AF kemungkinan dapat menurunkan stres oksidatif yang memicu apoptosis pada lapisan epitel kornea mata dengan proses shielding sumber paparan RGEM.

Body Mass Index, Waist-Hip Ratio and Fasting Blood Glucose Levels amongst the University Students Rury Tiara Oktariza; Viskasari Pintoko Kalanjati; Ni Wajan Tirthaningsih
Folia Medica Indonesiana Vol. 57 No. 1 (2021): March
Publisher : Universitas Airlangga

Overweight and obesity have been correlated to the higher risk for developing metabolic diseases in later life, i.e. DM type 2. We study the body mass index (BMI), the waist to hip ratio (WHR) and the fasting blood glucose levels (FBG) in the seemingly healthy male and female university students to comprehend these variables amongst the youth in Indonesia in 2019. The BMI and WHR of 150 male and female students aged 18-22 years old of the IIKBW, Kediri were measured by standardised anthropometry. The FBG was measured after 8 hours-minimum of fasting from the capillary blood drop using glucometer. Data was then analysed using SPSS 17 with level of significance of p<0.05. According to Asia-Pacific BMI classification, students were 30.7% obese with males significantly higher than females (p=0.016), 18% overweight (significantly higher in females, p=0.04), 36% normal and 15.3% underweight.When compared between genders, the WHR is significantly higher in males (p<0.001); whilst no significant differences in FBG (p=0.6). Four males and 5 females with FBG ≥ 100 mg/dl, whereas others were within normal limits. There are positive significant correlations between BMI and WHR in males and females (r=0.777, p<0.001; r=0.54, p<0.001, respectively). There is a significant positive correlation between the BMI and FBG with r=0.217, p=0.008; and between the WHR and FBG with r=0.21, p=0.01 amongst all students. In this study, male students have significantly higher BMI and WHR than females. Higher FBG was well observed in students with either higher BMI or WHR.

Case report: Dentigerous Cyst and Canine Impaction at the Orbital Floor Ferdian rizky Hutomo; Ellen Satya Pratiwi; Viskasari P Kalanjati; Andra Rizqiawan
Folia Medica Indonesiana Vol. 55 No. 3 (2019): September
Publisher : Faculty of Medicine, Universitas Airlangga

Dentigerous cysts are cysts of the epithelial lining of the jaws derived from the dental follicle of unerupted teeth. These cysts are often found during routine radiographic examination along with unerupted teeth. Dentigerous cysts are usually asymptomatic unless the size becomes large, thus causing swelling. This case report describes the management of dentigerous cyst in the upper left canine region with canine impaction to the orbital floor. Dentigerous cyst was treated with cyst enucleation but the impacted canine was not taken because of the magnitude of risk that can occur which was a disruption to the eye muscle. Conclusion. Treatment of dentigerous cysts can be performed by enucleation technique and management related the impacted tooth at the orbital floor needs a further evaluation consideration.

PROFIL PENDERITA GASTRO ESOPHAGEAL REFLUX DISEASE (GERD) DAN NON-EROSIVE REFLUX DISEASE (NERD) DI RSUD DR. SOETOMO SURABAYA Irvinia Septarizka Putri Radjamin; Iswan Abbas Nusi; Viskasari Pintoko Kalanjati
Majalah Biomorfologi Vol. 29 No. 1 (2019): Majalah Biomorfologi
Publisher : Universitas Airlangga, Surabaya, Indonesia

Background: Gastro Esophageal Reflux Disease (GERD) is a condition when food that had been ingested moves back up from the stomach to the esophagus periodically, causing heartburn. GERD cases that are followed up by esophagogastroduodenoscopy (EGD) can be diagnosed as Non-Erosive Reflux Disease (NERD) if there are no findings of mucosal damage at the esophagus. Objective: The objective is to study the overall prevalence of GERD and NERD patients on January until December of 2015, categorizing them according to age groups, gender, grade of esophageal mucosal damage according to Los Angeles grading, and also other EGD findings. Material and method: This is a descriptive research using secondary data collected from patients' medical record. Patients that are diagnosed as GERD or NERD are included as sample. Data are collected and processed by Microsoft Office Excel 2007. Result: A total of 122 medical records were collected, with 116 GERD patients and 6 NERD patients. There was increase of prevalence of GERD patients shown following the increase of age groups, while prevalence of NERD patients between age groups fluctuate. Both GERD and NERD patients are dominated by women, that is 62 patients (53.4%) and 5 patients (83.3%) respectively, compared to male, that is 54 GERD patients and 1 NERD patient. According to Los Angeles grading, the patients are mostly categorized as grade A (14.7%). However, there were 88 unclassified cases found so the result arguably needed a bigger sample and/ or data written in the medical record might not be clearly stated. The most dominant EGD finding in GERD patients was erosive gastritis (24.8%). Conclusion: There were 95% GERD patients and 5% NERD patients discovered in this study. The profile of GERD patients in this case was dominantly found in the age group of more than 50 years old, women, grade A, and with erosive gastritis in the EGD findings. The profile of NERD patients was not specific to a certain age group, but mostly found in women.

PROFIL PASIEN ENSEFALOKEL ANAK USIA 0 -18 TAHUN DI DEPARTEMEN BEDAH SARAF RSUD DR. SOETOMO SURABAYA Avida Marisa Ilmi; Viskasari Pintoko Kalanjati; Wihasto Suryaningtyas
Majalah Biomorfologi Vol. 29 No. 2 (2019): Majalah Biomorfologi
Publisher : Universitas Airlangga, Surabaya, Indonesia

Background: Data of encephalocele patient is rarely found in Indonesia, especially in East Java. Researcher conducted an observation aboutprofile of encephalocele patient age 0–18 years old at Department of Neurosurgery, Dr. Soetomo Hospital, Surabaya, Indonesia.Objective: To observe profile of encephalocele patient age 0–18 years at Department of Neurosurgery, Dr. Soetomo Hospital, Surabaya, Indonesia. Material and method: This is cross sectional observation research observing medical record of encephalocele patient age 0–18 years at Department of Neurosurgery, Dr. Soetomo Hospital, Surabaya, Indonesia from 2010 to 2012.This study also observeage groups, gender, address, and types of encephalocele. Results: 27 male and 23 female patients were included. From 5 types based on the defect location, 30 patients are diagnosed as nasofrontal encephalocele, nasoorbita is found at 17 patients, while nasofrontoorbita, maxilonasoorbita and nasoethmoorbita is found at 1 patient each. The most dominant age group is 0 – 3.5 years old (n=15). From 50 patients, 43 patients were from outside Surabaya.Conclusions: The number of male patients diagnosed with encephalocele were slightly higher compared to female patients. Nasofrontal type was the predominant type amongst other types. The majority of encephalocele patients were 0 – 3.5 years old. These patients mostly were from outside of Surabaya city.

BODY MASS INDEX (BMI) OF CHILDREN WITH TETRALOGY OF FALLOT (TOF) Ovin Nada Saputri; Viskasari P. Kalanjati; Mahrus A. Rahman
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Background: Malnutrition is a common cause of morbidity and mortality amongst children with TOF. Objective: To analyze the BMI profile of children with TOF aged 0 – 18 years at Pediatric Department, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Materials and Methods: A cross-sectional study of the BMI from the medical record of TOF patients aged 0 – 18 years at the Pediatric Department, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, since January 2016 to December 2017 was conducted. The data included gender, age group, demographic distribution, weight, and height. BMI was calculated by WHO formula reference; body weight (kg) divided by body height squared (m2), which was converted into z-score histogram. BMI classification was guided by the Government’s Anthropometry Standards for Nutritional Status Assessment. Result: From 84 TOF patients, there were 43 males (51%) and 41 females (49%). The most dominant age group was 0 – 4 years old (n=47;56%). The majority of patients were from outside of Surabaya (n=64;76.2%). Based on their BMI, 36 patients (42.9%) had severe underweight, 10 patients (11.9%) were underweight, and 35 patients (41.7%) were normal, whilst the rests (3.6%) were overweight. Conclusion: The number of male patients was slightly higher than female patients. The majority of TOF patients were 0 – 4 years old and resided out town of Surabaya. The predominant BMI found was the underweight and severe underweight below normal BMI.

PROFILE OF EPILEPSY PATIENTS IN PEDIATRIC WARD AT DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA IN THE PERIOD OF JANUARY-DECEMBER 2017 Dewi Sekarsari; Viskasari P. Kalanjati; Abdulloh Machin; Prastiya I. Gunawan
Majalah Biomorfologi Vol. 30 No. 2 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i2.2020.34-38

Background: Various risk factors of epilepsy in children had been reported although differences were found amongst regions. Objective: To identify the profile of epilepsy patients and previous febrile seizure history in children aged 0-17 years at Pediatric Ward, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2017. Materials and Methods: This was a cross-sectional retrospective study, using secondary data from medical records of epilepsy patients with febrile seizure history in children aged 0-17 years old at Pediatric Ward, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in the period of January-December 2017. Data analysis was done using t-test and Chi- Square test (Microsoft Excel 2007 and SPSS 22). The level of significance was p<0.05. Results: Seventy-four male and 38 female patients were included. Febrile seizure history was observed in 42 patients and there was no significant difference between febrile seizure history and prevalence of epilepsy. The general type of seizure was found in 79 patients; mostly from Surabaya, Indonesia and the parents’ occupation was private employee. The most observed type of seizure was general type. Conclusion: In this study, epilepsy was predominantly found in males than females; and a significant number of the patients were without febrile seizure history. General type of seizure was the most common type amongst others. These patients were mostly from Surabaya, Indonesia, whose parents' occupation was private employees.

COMORBIDITIES OF MYASTHENIC CRISIS PATIENTS ACCORDING TO AGE AND GENDER IN DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA IN 2017-2019 Andi Muh Rahul Alfaidin; Viskasari P Kalanjati; Mudjiani Basuki
Majalah Biomorfologi Vol. 32 No. 1 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i1.2022.1-5

Highlight:1. Patients with myasthenia gravis (MG) can have both autoimmune and non-autoimmune comorbidities.2. MG patients were predominantly aged >50 years, females and the commonest comorbidity are hypertension and diabetes mellitus.3. Age and comorbidities were found to have significant correlation among these patients, but not between gender and comorbidities.Abstract:Background: There are limited studies on the comorbidities of myasthenic crisis (MC) associated with age and gender, specifically from Indonesia. These data might be valuable for treatment to improve the outcome of these patients. Objective: To analyze the correlation between age and gender with the comorbidities amongst the MC patients admitted in the ICU of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2017-2019. Materials and methods: A retrospective cross-sectional analytic study was conducted on 25 medical records of MC patients who fulfilled the inclusion and exclusion study criteria. Descriptive statistics and Chi-square tests were done to determine the potential correlation between variables (significant level of p<0.05). Results: The age of MC patients was £50 years (80%) and >50 years (20%) while the gender predominantly found were females (68%) with 32% males. A significant correlation was found between age and comorbidities (p=0.002) whilst not between gender and comorbidities (p=0.115). The most common comorbidities observed were hypertension (30%) and diabetes mellitus (20%). Conclusion: There were 40% of patients found with comorbidities. There was a significant association between age and comorbidities found amongst myasthenic crisis patients, whilst no significant association was found between gender and comorbidities.

Co-Authors Abdurachman Abdurachman Abdurachman Abdurachman Abdurachman Aditya, Dwi Martha Nur Akbar, Ghifar Al Muqsith Alfi Amelinda Andi Muh Rahul Alfaidin Andra Rizqiawan Anna Lewi Santoso Annette dÃ¢Â€Â™Arqom, Annette Anung Putri Illahika Arlia Ayu Damayanti Arsyi, Danial Habri Avida Marisa Ilmi Azlin Muhammad Mohd Yasin Balogun, Olubunmi Bambang E. Suwito Bambang E. Suwito Bambang Edi Suwito Brilianti, Natasya Nurvita Damayanti, Arlia Ayu Desy Purwidyastuti Dewi Ratna Sari Dewi Sekarsari Dewi, Arni Kusuma Dion K. Dharmawan Dion Krismashogi Dharmawan Dzanuar Rahmawan Dzanuar Rahmawan Ellen Satya Pratiwi Etha Dini Widiasi Farabi, Moh. Reza Ferdian rizky Hutomo Fidiana H. Hoediyanto Haryanto Alimsardjono HERAWATI, LILIK Hidayaturrahmi, Hidayaturrahmi Ida Lestari Harahap Intan Anggun Pratiwi Irmawan Farindra Irvinia Septarizka Putri Radjamin Iswan Abbas Nusi Jason Lefranda Jocelino Siswanto Jongky H. Prajitno Joni Wahyuhadi, Joni Krisnawan A. Pradana Krisnawan A. Pradana Kurniawaty, Yuni Kusuma E. Purwantari Kusuma Eko Purwantari Lucky Prasetiowati Machin, Abdulloh Made Pury Pratiwi Mahdi, Rayhan B Mahrus A Rahman, Mahrus A Mariana Wahjudi Mayang Rizki Anggraeni Meutia Maulina Nasution, Muhammad Husni Fansury Noer Halimatus Syakdiyah Nurina Hasanatuludhhiyah Oktariza, Rury Tiara Ovin Nada Saputri Pamungkas, Dimas Bathoro Bagus Peppy Nawangsasi Permana, Putu Bagus Dharma Pradana, Krisnawan Andy Prastiya I. Gunawan Prastiya Indra Gunawan Pratiwi, Octaviana Galuh Raden Argarini Rahadian I Susilo Rahmawan, Dzanuar Reza Maulana Rezy R. Melbiarta Rezy Ramawan Melbiarta Rimbun Rimbun Risdiansyah Risdiansyah Rury T. Oktariza Sakina Sakina Soetjipto Soetjipto Susila, I Made Dwi Yudiartana Putra Syamhadi, Maya Rahmayanti Taya Elsa Savista Tirthaningsih, Ni Wajan Visuddho Warda Elmaida Rusdi Wardhana, Teddy Heri Winnie Nirmala Santosa Yudhono, Anggit Satriyo Yusuf Salim Yusuf Salim Zulhabri Othman

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