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All Journal Jurnal Inovasi Farmasi Indonesia Medfarm: Jurnal Farmasi dan Kesehatan
prabowo, pulung
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Chemistry Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Analisis Profil Terapi dan Evaluasi Kualitas Peresepan Pada Pasien COVID-19 Rawat Inap di Rs X Jawa Tengah: Therapeutic Profile Analysis and Prescription Quality Assessment for COVID-19 Inpatients Hospital X in East Java Mawarni, Okky Intan; winartiana, Winartiana; Putri, Elsa Mahardika; Pratiwi, Maharani Dwi; Prabowo, Pulung; Ratnanigrum, Elly Rakhmawati
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 6 No. 2 (2025): Volume 6, No.2 Juni 2025
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v6i2.6530

Abstract

COVID-19, caused by SARS-CoV-2, has a high transmission and mortality rate, The variability in therapies administered to patients necessitates an evaluation of treatment patterns among COVID-19 patients to ensure effective therapeutic outcomes. This study aims to analyze the therapy profiles and evaluate prescription patterns of hospitalized patients at General Hospital X, Central Java, based on the COVID-19 Management Protocol, 2nd edition (January 2021). A retrospective descriptive method with purposive sampling was applied to 100 hospitalized COVID-19 patients in 2022. The results showed that the majority of patients were male (55%), aged 40–59 years (45%), had moderate disease severity (77%), a treatment duration of 1–10 days (89%), and a recovery rate of 62%. The most frequently used drug therapies included respiratory medications (19%), gastrointestinal drugs (17%), vitamins (16%), antibiotics (11%), and antivirals (11%). Prescription evaluation revealed 100% drug suitability, 100% correct dosage, 97% appropriate dosing intervals, and 92% correct duration of administration.
Analysis of Drug Use and Potential Interactions in Type 2 Diabetes Inpatients at a Type C Hospital, Kediri (2024) dhafin, anis akhwan; Wiryani, Luh Santhi Utami; Putri, Elsa Mahardika; Herman, Herman; Prabowo, Pulung; Yuniarto, Prayoga Feri; Winartiana, Winartiana
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.641

Abstract

Bachelor of Pharmacy, Universitas Mahasaraswati Denpasar, Indonesia Corresponding Author: anisdhafin13@unik-kediri.ac.id ABSTRACT Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a high prevalence and frequent comorbidities, particularly hypertension, which often require multidrug therapy and increase the risk of drug interactions. This study aimed to analyze the pattern of antidiabetic drug use and the potential for drug interactions in hospitalized patients with T2DM at a type C hospital in Kediri City during June–December 2024. The research employed a retrospective descriptive design using medical record data of 44 patients who met the inclusion criteria. Data were analyzed descriptively and presented in frequency distribution tables. Results showed that the most commonly prescribed drug class was biguanides (26.25%), followed by sulfonylureas (21%), insulin (21%), and α-glucosidase inhibitors (12.5%). Combination therapy was widely used, particularly the combination of two oral antidiabetic agents. Potential drug interactions were identified in 72.73% of patients, with moderate interactions being the most frequent (78.13%), followed by minor (12.5%) and major (9.38%) interactions. The most common interactions included metformin with amlodipine or ramipril (moderate severity), captopril with hydrochlorothiazide (minor severity), and simvastatin with amlodipine (major severity). However, in this study polypharmacy was defined as the concomitant use of ≥5 medications. These findings indicate that such polypharmacy in T2DM patients with hypertension substantially increases the likelihood of drug interactions, underscoring the importance of careful monitoring and rational prescribing to improve patient safety
Co-Authors Anis Akhwan Dhafin Mawarni, Okky Intan Pratiwi, Maharani Dwi Putri, Elsa Mahardika Ratnanigrum, Elly Rakhmawati Winartiana, Winartiana Wiryani, Luh Santhi Utami Yuniarto, Prayoga Feri