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All Journal Dental Journal (Majalah Kedokteran Gigi) Journal of Indonesian Dental Association
Harsas, Nadhia Anindhita
Department Of Periodontia, Faculty Of Dentistry, Universitas Indonesia
Dentistry

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Combination of Platelet-rich Fibrin (PRF) in Advanced Periodontitis Stage Treatment Harsas, Nadhia Anindhita; Tadjoedin, Fatimah Maria; Sulijaya, Benso; Hutomo, Dimas Ilham; Purba, Melinda Rabekka; Sasri, Cahyaning Wulan
Journal of Indonesian Dental Association Vol 6 No 2 (2023): October
Publisher : Indonesian Dental Association

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Abstract

Introduction: The treatment of advanced periodontitis has been a challenge for clinicians. Platelet-rich fibrin (PRF) is a second-generation platelet concentrate that contains various growth factorss and cytokines that promote tissue regeneration. The use of PRF in combination with other regenerative materials and techniques has been shown to be effective in the treatment of intrabony defects. This case series aims to evaluate the efficacy of PRF combinations in the regenerative treatment of patients with advanced periodontitis. Case report: Two patients diagnosed with advanced periodontitis (stage III/IV grade C) were selected for this study. After the completion of periodontal initial therapy, there were still pockets with a probing depth ≥ 5 mm (5–10 mm). Therefore, surgical interventions were planned. The first case used the combination of PRF with bone graft and guided tissue regeneration (GTR), while open flap debridement (OFD) with the addition of PRF and bone graft to create sticky bone was done in the second case. Three to five months of follow-up showed favorable outcomes, as evidenced by reductions in probing depth (PD), gains in clinical attachment level, and filling of bone defects, as well as improvements in patient comfort and rapid wound healing. Conclusion: The combination of PRF with grafting material and/or GTR has been shown to be a beneficial therapeutic approach for periodontal regenerative therapy. Platelet-rich fibrin in periodontal surgery may accelerate the tissue healing process.
Curettage Treatment on Stage III and IV Periodontitis Patients Harsas, Nadhia Anindhita; Safira, Dhia; Aldilavita, Hanli; Yukiko, Ingetiarani; Alfarikhi, Mochamad Prabu; Saadi, Muhammad Tsany; Feria, Qonita; Kiranahayu, Rarasih; Muchlisya, Shabrina
Journal of Indonesian Dental Association Vol 4 No 1 (2021): April
Publisher : Indonesian Dental Association

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Introduction: Periodontitis is an inflammatory disease of teeth supporting tissue caused by a group of specific microorganism that causes progressive damage to the periodontal ligament and alveolar bone. Periodontal pocket is one of the most important clinical features of periodontal disease. This case report aims to evaluate the results of curettage in periodontitis cases with different stages and grades. Case reports: This report consists of two cases. The first case is a 41-year-old female patient with a chief complaint of gum bleeding during brushing and tooth mobility. Intraoral examination showed gingival redness and swelling, positive papillary bleeding index (PBI) in all regions, and an OHI-S score of 3.16 (poor). A probing depth of 4-5 mm was present on the upper right canine and the lower left central incisor. Gingival recession of 1 mm was also present on the upper right canine. Radiographic examination showed horizontal bone defect that reached the cervical third of the root on the upper right canine and the middle third of the root on the lower left central incisor. The second case is a 61-year-old female patient with a chief complaint of tooth hypersensitivity and tooth mobility since three years ago. Intraoral examination showed gingival redness and swelling with positive PBI in all regions. Oral Hygiene Index- Simplified (OHI-S) score was 3.6 (poor). A probing depth of 4-5 mm and gingival recession was present on both lower left incisors. Grade 1 tooth mobility was also present on the lower left central incisor. Radiographic examination showed horizontal bone defect reaching the apical third of the root. Curettage was performed for both cases after a thorough scaling and root planing. Conclusion: Curettage as a treatment for patients with chronic periodontitis after 4 weeks shows an improvement of patient’s Oral Hygiene Index - Simplified (OHI-S) score and reduced probing depth.
Relationship between the levels of awareness and knowledge of periodontitis in diabetic patients at a Dental Hospital during the COVID-19 pandemic Nathania, Irene; Harsas, Nadhia Anindhita; Natalina; Tadjoedin, Fatimah Maria
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p243-250

Abstract

Background: Diabetes mellitus (DM) and periodontitis are the most prevalent human diseases. Diabetes worsens the periodontal condition, but periodontitis also hampers glycemic control in diabetic patients. Based on staging and grading, the latest periodontitis classification puts DM as one of the grade modifiers. Periodic periodontal maintenance prevents reinfection and could help people with diabetes maintain effective glycemic control. Dental health education and periodontal disease awareness are crucially needed for diabetic patients, especially during the pandemic. Purpose: This study aimed to examine the relationship between levels of awareness and knowledge of periodontitis in diabetic patients during the COVID-19 pandemic. Methods: A closed-ended questionnaire was distributed to new patients referred to the Periodontology Clinic of the Dental Hospital of Universitas Indonesia. Patients' data were collected during the COVID-19 pandemic from January to June 2021. Results: Eighty-four patients participated, of which 34.5 % were diabetic patients with periodontitis. Statistically, significant differences (P < 0.05) were found between levels of awareness and knowledge of periodontitis among diabetic patients and nondiabetic patients (both groups are suffering periodontitis). Awareness and knowledge of periodontitis are inversely correlated with their current clinical periodontal status, therefore patients with less awareness and knowledge have more severe periodontitis. Conclusion: Lack of awareness and knowledge of periodontitis was found among both nondiabetic and diabetic periodontitis patients. Dental health education is required to improve understanding and awareness of the relationship between periodontitis and DM.
Curettage Treatment on Stage III and IV Periodontitis Patients Nadhia Anindhita Harsas; Dhia Safira; Hanli Aldilavita; Ingetiarani Yukiko; Mochamad Prabu Alfarikhi; Muhammad Tsany Saadi; Qonita Feria; Rarasih Kiranahayu; Shabrina Muchlisya
Journal of Indonesian Dental Association Vol. 4 No. 1 (2021): April
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v4i1.501

Abstract

Introduction: Periodontitis is an inflammatory disease of teeth supporting tissue caused by a group of specific microorganism that causes progressive damage to the periodontal ligament and alveolar bone. Periodontal pocket is one of the most important clinical features of periodontal disease. This case report aims to evaluate the results of curettage in periodontitis cases with different stages and grades. Case reports: This report consists of two cases. The first case is a 41-year-old female patient with a chief complaint of gum bleeding during brushing and tooth mobility. Intraoral examination showed gingival redness and swelling, positive papillary bleeding index (PBI) in all regions, and an OHI-S score of 3.16 (poor). A probing depth of 4-5 mm was present on the upper right canine and the lower left central incisor. Gingival recession of 1 mm was also present on the upper right canine. Radiographic examination showed horizontal bone defect that reached the cervical third of the root on the upper right canine and the middle third of the root on the lower left central incisor. The second case is a 61-year-old female patient with a chief complaint of tooth hypersensitivity and tooth mobility since three years ago. Intraoral examination showed gingival redness and swelling with positive PBI in all regions. Oral Hygiene Index- Simplified (OHI-S) score was 3.6 (poor). A probing depth of 4-5 mm and gingival recession was present on both lower left incisors. Grade 1 tooth mobility was also present on the lower left central incisor. Radiographic examination showed horizontal bone defect reaching the apical third of the root. Curettage was performed for both cases after a thorough scaling and root planing. Conclusion: Curettage as a treatment for patients with chronic periodontitis after 4 weeks shows an improvement of patient’s Oral Hygiene Index - Simplified (OHI-S) score and reduced probing depth.
Combination of Platelet-rich Fibrin (PRF) in Advanced Periodontitis Stage Treatment Nadhia Anindhita Harsas; Fatimah Maria Tadjoedin; Benso Sulijaya; Dimas Ilham Hutomo; Melinda Rabekka Purba; Cahyaning Wulan Sasri
Journal of Indonesian Dental Association Vol. 6 No. 2 (2023): October
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v6i2.1075

Abstract

Introduction: The treatment of advanced periodontitis has been a challenge for clinicians. Platelet-rich fibrin (PRF) is a second-generation platelet concentrate that contains various growth factorss and cytokines that promote tissue regeneration. The use of PRF in combination with other regenerative materials and techniques has been shown to be effective in the treatment of intrabony defects. This case series aims to evaluate the efficacy of PRF combinations in the regenerative treatment of patients with advanced periodontitis. Case report: Two patients diagnosed with advanced periodontitis (stage III/IV grade C) were selected for this study. After the completion of periodontal initial therapy, there were still pockets with a probing depth ≥ 5 mm (5–10 mm). Therefore, surgical interventions were planned. The first case used the combination of PRF with bone graft and guided tissue regeneration (GTR), while open flap debridement (OFD) with the addition of PRF and bone graft to create sticky bone was done in the second case. Three to five months of follow-up showed favorable outcomes, as evidenced by reductions in probing depth (PD), gains in clinical attachment level, and filling of bone defects, as well as improvements in patient comfort and rapid wound healing. Conclusion: The combination of PRF with grafting material and/or GTR has been shown to be a beneficial therapeutic approach for periodontal regenerative therapy. Platelet-rich fibrin in periodontal surgery may accelerate the tissue healing process.
Co-Authors Aldilavita, Hanli Alfarikhi, Mochamad Prabu Benso Sulijaya, Benso Cahyaning Wulan Sasri Dhia Safira Dimas Ilham Hutomo Fatimah Maria Tadjoedin Feria, Qonita Hanli Aldilavita Hutomo, Dimas Ilham Ingetiarani Yukiko Kiranahayu, Rarasih Melinda Rabekka Purba Mochamad Prabu Alfarikhi Muchlisya, Shabrina Muhammad Tsany Saadi Natalina Nathania, Irene Purba, Melinda Rabekka Qonita Feria Rarasih Kiranahayu Saadi, Muhammad Tsany Safira, Dhia Sasri, Cahyaning Wulan Shabrina Muchlisya Tadjoedin, Fatimah Maria Yukiko, Ingetiarani