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Desianti, Ginanjar Arum
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The Evolution of Transbronchial Lung Biopsy Guidance Alatas, Mohammad Fahmi; Bies, Asri Liqditta; Prasenohadi, Prasenohadi; Soehardiman, Dicky; Aniwdyaningsih, Wahju; Elhidsi, Mia; Desianti, Ginanjar Arum; Reisa, Tina; Rasmin, Menaldi
Respiratory Science Vol. 5 No. 2 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i2.170

Abstract

Histological confirmation of lung lesions is necessary prior to determining further management. Imaging preparation is needed to find the biopsy site such as a computed tomography scan. Imaging helps to trace the position of lung lesions that are peripheral and not visualized by bronchoscope. However, along with the discovery of small lesions and peripheral location, two-dimensional imaging alone remains suboptimal. Therefore, to reach lung lesions peripherally would need to a guide through the bronchial. Subsequently, the method of guiding transbronchial biopsy evolved. Namely, real-time fluoroscopy, radial-probe endobronchial ultrasound, virtual bronchoscopy navigation and electromagnetic bronchoscopy navigation are guiding modalities with each of their advantages and disadvantages. Several biopsy modalities are used in combination to increase the accuracy of diagnosis. Careful analysis in planning and an understanding of the limitations and advantages of diagnostic modalities must be considered in deciding which method to choose.
Oxygen Therapy in Exacerbation of Interstitial Lung Disease Aritonang, Rachel S; Fachrucha, Fanny; Elhidsi, Mia; Desianti, Ginanjar Arum
Respiratory Science Vol. 4 No. 3 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i3.129

Abstract

Interstitial lung diseases (ILD) are a group of diseases that involve damage in the interstitial tissue, causing diffusion disorders which ultimately lead to hypoxemia. One of the conditions that aggravate hypoxemia in ILD patients is acute exacerbation. Acute exacerbation is a condition of deterioration of ILD that can occur in less than 1 month. During an acute exacerbation, there will be a worsening of the HRCT pattern with increased ground glass opacities and a worsening of the clinical picture including hypoxemia. Acute exacerbations are closely related to increased mortality rates. Oxygen administration is one of the supportive therapies that can be given to acute exacerbations. The provision of oxygen therapy is adjusted to the patient's needs using a high-flow nasal cannula, non-invasive ventilation, invasive mechanical ventilation, and extracorporeal membrane oxygenation.