Alnaz, Ahmad Razi Maulana
Unknown Affiliation

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Faktor yang Memengaruhi Penggunaan Pengobatan Herbal pada Pasien di Puskesmas Pekan Labuhan tahun 2023 Alnaz, Ahmad Razi Maulana; Nasution, Rizki Fauzan Ghali; Nasution, Abdul Hakim; Fauzi, Muhammad Rado; Annisa, Dinda; Alifa, Cut Safira; Amelia, Rina
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 1 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i1.13656

Abstract

ABSTRAK Latar Belakang. Indonesia kaya akan keanekaragaman hayati terutama di bidang pertanian, yang menyebabkan tingginya angka pemanfaatan herbal untuk pengobatan tradisional. Praktik tersebut dipengaruhi oleh banyak faktor terutama faktor sosio-demografis, ekonomi, pendidikan dan lainnya.Tujuan. Untuk menganalisis  jumlah dan tipe-tipe dari pengobatan herbal di Puskesmas Pekan labuhan dan juga faktor yang memengaruhi penggunaan obat-obatan herbal.Metode.Penelitian ini merupakan penelitian deskriptif dan analitik observasional dengan desain potong lintang, pada 119 pasien dewasa di Puskesmas Pekan Labuhan pada rentang waktu penelitian. Sampel diambil dengan metode purposive sampling pada pasien yang datang ke puskesmas. data dikumpulkan menggunakan kuesioner. Data di analisis secara univariat dan bivariat menggunakan tes pearson χ2  atau Fischer's Exact test menggunakan Statistical Package for Social Science (SPSS) versi ke-21 untuk windows pada interval kepercayaan 95%.Hasil. Penggunaan pengobatan herbal pada masyarakat sekitar Puskesmas Pekan Labuhan sebesar 49%. Umumnya pengobatan herbal digunakan sebagai obat komplementer, dengan jamu sebesar 39% dan pil ekstrak 23.7%. Penggunaan pengobatan herbal tersebar merata diantara kelompok demografis dan faktor pengobatan. Terdapat 2 faktor yang paling memengaruhi yaitu kepercayaan terhadap keamanan dari pengobatan herbal (PR 3.58, p<0.001) dan persepsi akan mahalnya pengobatan konvensional (PR 1.69, p=0.013). Kesimpulan : Penggunaan pengobatan herbal umum digunakan di lingkungan Puskesmas Pekan Labuhan, yang tersebar secara merata dalam berbagai factor latar belakang sosiodemografis. Oleh karena itu, dibutuhkan penelitian lebih lanjut yang lebih detail dan dengan cakupan yang lebih luas   Kata Kunci: Pusat Kesehatan Masyarakat, Pengobatan alternatif, Pengobatan herbal, Pengobatan komplementer, Pengobatan tradisional   ABSTRACT Background. Indonesia rich in biodiversity mainly in agriculture, causing high number of herbal utilization for medication among local traditional medication. The practice was affected by many factors mainly sociodemographic, economic, education, and other factors. Objectives. To analyze numbers and types of herbal medication in Pekan Labuhan Primary Health Centre and factors affecting the utilization.Methods. This is a descriptive and analytic observational study which is conducted in cross sectional design, on 119 selected adult in the Pekan Labuhan Primary Health Care Center visiting during research time range. Samples were obtained by purposive sampling on patient presenting to the PHC. Data were collected using questionnaires. Data were analyzed with univariate, bivariate analysis was using Pearson χ2 test or Fischer’s Exact test using Statistical Package for Social Science (SPSS) version 21 for windows on Confidence Interval of 95%.Results. Utilization of herbal medication among public around Pekan Labuhan PHC were approximately 49% of total. Most of herbal medication were used as complementary medicine using jamu for 39% and extract pills for 23.7%.  The use of herbal medication were similar among groups of demographic and medication factors, however we reported 2 main affecting factors which were local belief on safety of herbal medication (PR 3.58, p<0.001) and expensive perception of conventional medication (PR 1.69, p=0.013)Conclusion : Utilization of herbal medication is common around Pekan Labuhan PHC, which were similar on most factors. Hence, further detailed and larger research will be required to be conducted Keywords: Alternative Medicine, Complementary Medicine, Herbal Medication, Traditional medicine, Primary Healthcare Center
Potency of Various MicroRNA as Sputum Biomarker in Lung Cancer Alnaz, Ahmad Razi Maulana; Abdillah, Aqyl Hanif; Ridha, Rasyid
Smart Medical Journal Vol 5, No 1 (2022): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v5i1.54585

Abstract

Introduction: Lung cancer is one the deadliest cancer known. Current method using low-dose CT scan to screen lung cancer applied are proved to reduce mortality, but lack in accuracy leading to overdiagnosis. Current researches are mostly seeking for a non-invasive and cost-effective method, hence biomarkers such as microRNA has a potency to screen and diagnose lung cancer. This literature review aimed to discuss the potency of microRNA in sputum as a biomarker in screening lung cancer.Methods: The study is conducted by literature searching for related journals in search engines such as PubMed, Science Direct, and Google Scholar with keywords. 35 articles were included with relevance and within 10 years publication.Result: MicroRNA is a short non-coding RNA which regulates gene expression. It acts in an oncogene or tumor suppressor gene regulation. DNA mutations or defects occurred in cancer particularly in lung cancer causes increase or decrease of microRNA expression. Alterations of microRNA expression in sputum detected by rt-PCR may represent progressions of lung cancer from a cell cycle dysregulation and provides better sensitivity and specificity among other biomarkers. Combinations of miRNA species offer increase of  sensitivity and specificity. Particular types of microRNA are able to classify the types of lung cancer in progress.Conclusion: MicroRNA has the promising potency and strong accuracy with a non-invasive and cost-effective procedure in detecting early signs of lung cancer occurrence and can be further applied as biomarker used in lung cancer.Keywords: Biomarker; Lung Cancer; microRNA; Screening; Sputum