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All Journal Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Respiratory Science Indonesian Journal of Cancer
Faisal, Hana Khairina Putri
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Indonesia – Persahabatan National Respiratory Hospital, Jakarta
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Pediatric Hemoptysis Hana Khairina Putri Faisal; Faisal Yunus; Nastiti Rahajoe
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.189

Abstract

Hemoptysis or expectoration of blood is one of the respiratory symptoms in children, hemoptysis is hard to detect because it is often swallowed. The common causes of hemoptysis in adults include bronchiectasis, tuberculosis, pulmonary mycosis, and lung cancer. On the other hand, hemoptysis in children is often caused by tracheobronchitis, pneumonia, bronchiectasis in cystic fibrosis, and foreign body aspiration. Bleeding of the pulmonary artery or bronchial artery is the cause of hemoptysis. Upper airway examination is important to rule out epistaxis as the cause of hemoptysis. The primary objectives of hemoptysis management are asphyxia management, bleeding cessation, and treatment of the underlying disease. When all other treatments fail to stop the bleeding, surgery is recommended.
A COVID-19 Ringan Pada Tenaga Medis: Evaluasi Temuan Klinis dan Risiko Transmisi Mahrani; Hana Khairina Putri Faisal; Paramita Khairan; Iffa Mutmainah; Fitriana Nur Rahmawati; Sarah Shafa Marwadhani; Gadistya Novitri Adinda; Uti Sari; Pukovisa Prawirohardjo
Majalah Kedokteran Indonesia Vol 70 No 4 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.4-2020-223

Abstract

Objective: Since December 2019, COVID-19 has become a global concern causing more than thousands of deaths worldwide. The major challenge in fighting against this new emerging disease is the limited data regarding the heterogeneity of its clinical and epidemiological features. We aim to fill this knowledge gap by evaluating a mild case of COVID-19 infecting a health worker in Indonesia.Method: We report a 31-year-old male doctor who was hospitalized for mild pneumonia with positive SARS-CoV-2 swab testResult: This case presents an estimated incubation period of 2 days. The patient showed mild upper respiratory symptoms without significant pneumonia symptoms, however mild pneumonia was confirmed by the presence of fever and pulmonary infiltrates on imaging. Despite the seemingly mild symptoms, there was a complex systemic reaction as thrombocytopenia and elevated aminotransferase enzyme occurred. The patient is a health worker susceptible to SARS-CoV-2 transmission with a close contact history with a suspected COVID-19 patient, without wearing an adequate personal protective equipment (PPE).Conclusion: Patients with mild presentation of COVID-19 could exhibit a complex systemic reaction and organ injury. The use of an appropriate PPE among health workers is crucial to prevent patient-to-doctor transmission.
Primary Pulmonary Sarcoma Coinfected with Pulmonary Tuberculosis: A Case Report Dea Putri Audina; Sita Laksmi Andarini; Hana Khairina Putri Faisal; Prasenohadi Prasenohadi; Jamal Zaini; Herawati Hidajat
Indonesian Journal of Cancer Vol 17, No 3 (2023): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v17i3.991

Abstract

Introduction: Pulmonary tuberculosis (TB) and malignancy are conditions with similar respiratory diseases and they are even known to coexist simultaneously. Therefore, accurate diagnosis of each disease is crucial to ensure precise treatment. This case study showed the coexistence of pulmonary TB and primary pulmonary sarcoma.Case Presentation: A 62-year-old male presented with a 3-month history of dyspnea, which worsened within 3 days. Before hospitalization, there were complaints of left chest pain, fatigue, loss of appetite, weight loss within 5 months, and night sweats. The patient who was a heavy smoker had experienced hemoptysis in the past 5 months. Upon physical examination, an increased respiratory rate and decreased oxygen saturation level. Furthermore, there were asymmetrical thorax movements, dull percussion on the left side, and decreased vesicular breathing sound on the left hemithorax, with no rhonchi or wheezing. A chest x-ray showed a destroyed left lung, while scanning confirmed left lung atelectasis and indicated a suspected mass within or around the left bronchus causing total obstruction in the main left bronchus. The bronchoscopy procedure identified a mass blocking the left main bronchus. However, a biopsy yielded inconclusive results. A rapid molecular test of TB detected Mycobacterium tuberculosis, which was discovered to be Rifampicin sensitive. As a result, the patient was treated daily with 4 fixed drug combinations for anti-TB. Despite the treatment, the complaint was not resolved within the next 3 months, as there was still a disease of cough in the form of mass-like phlegm, which uncovered a malignancy focus cell with differential diagnosis of pleomorphic sarcoma and sarcomatoid carcinoma.Conclusions: Lung malignancy not only overlapped with but also occurred simultaneously alongside lung TB. Therefore, it was crucial to establish a clear diagnosis in patients with chronic respiratory disease.
Fungal Profile in Patients with Lung Cancer Receiving First-Line Chemotherapy Faisal, Hana Khairina Putri; Aziziah, Aziziah; Pane, Irene Audrey Davalynn; Hasyim, Ammar Abdurrahman; Zaini, Jamal; Rozaliyani, Anna
Jurnal Respirasi Vol. 11 No. 3 (2025): September 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.3.2025.250-255

Abstract

Introduction: Patients with lung cancer are vulnerable to opportunistic infections, particularly fungal pulmonary infections such as those caused by Aspergillus spp., due to immunosuppression from both the disease and chemotherapy. Despite the clinical significance of these infections, data on their prevalence and associated factors in patients with lung cancer remain limited. This study aimed to determine the prevalence of Aspergillus spp. and identify associated factors in patients with lung cancer who underwent first-line chemotherapy at a national respiratory referral hospital in Indonesia. Methods: A cross-sectional study was conducted among 50 patients with lung cancer who had completed at least three cycles of chemotherapy. Sputum cultures were performed using Sabouraud dextrose agar (SDA), and serum immunoglobulin G (IgG) antibodies were tested using immunochromatographic assays. Demographic, clinical, and radiological data were collected. Bivariate and multivariate logistic regression analyses were used to identify factors associated with Aspergillus spp. infection. Results: Aspergillus spp. was detected in 92.0% of patients via sputum culture, with A. niger and A. fumigatus as the most common isolates. Over 30% showed co-colonization with other fungal species, such as Candida. Multivariate analysis revealed that a high Brinkman Index was independently associated with Aspergillus spp. colonization (p<0.05). Serum IgG antibody positivity was low (4%). Conclusion: There was a high prevalence of Aspergillus spp. colonization among patients with lung cancer undergoing chemotherapy, with smoking history emerging as a key risk factor. Targeted fungal screening is recommended, especially in heavy smokers, to facilitate early detection and improve outcomes.
Pulmonary Aspergilloma Co-Existing with Pulmonary Tuberculosis: A Case Report in Type 1 Diabetes Mellitus (T1DM) Patient Kirana, Widya Tria; Faisal, Hana Khairina Putri; Kitagawa, Hiroki; Setiawan, Gigih; Yunus, Faisal
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.213-219

Abstract

Introduction: Pulmonary aspergilloma is a disease frequently found in immunocompromised patients. In Indonesia, around 18% of diabetes mellitus (DM) patients suffer from chronic pulmonary aspergilloma. However, data on type 1 DM (T1DM) are still limited. Case: We presented the case of a 22-year-old male admitted to the emergency room due to hemoptysis of approximately 200 ml within six hours before admission, nonspecific chest pain during cough, fever, night sweats, and weight loss of 3 kg over the last months. The patient had a history of T1DM and no prior history of respiratory diseases. Physical examination showed tachycardia, tachypnoea, subfebrile, normal body mass index, and rhonchi on the left thorax. Routine laboratory tests revealed increased blood sugar level (503 mg/dL) and HbA1c 16.4%. Chest X-ray and high-resolution computed tomography (HRCT) showed a cavity with an opaque lesion, crescent sign, consolidation, and reticulonodular infiltrate on the left lung. Rapid molecular tests, tuberculosis (TB), and serum galactomannan (GM) were negative. The patient was diagnosed with pulmonary aspergilloma, T1DM, and clinical TB. He was treated with fluconazole, insulin, and a fixed-dose combination of anti-TB. The patient refused the surgery procedure. Immediately, the hemoptysis stopped, blood glucose level was normal, and concomitant with weight gain. Conclusion: Due to innate and acquired immunity impairment, T1DM is a risk factor for pulmonary infections, including TB and pulmonary aspergilloma. Chest HRCT may help diagnose fungal balls. Though the patient refused to undergo surgery, administering antifungal, anti-TB drugs, and glucose control as initial treatment presented a good prognosis in the patient.
Malignant Pleural Effusion: A Contemporary Approach to Diagnosis and Personalized Management Theresia Rasta Karina; Hana Khairina Putri Faisal; Mia Elhidsi
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.214

Abstract

Malignant pleural effusion (MPE) is a manifestation of advanced malignancy characterized by abnormal accumulation of pleural fluid due to tumor cell infiltration. It most commonly originates from lung, breast cancer, or lymphoma and is associated with dyspnea, chest pain, and impaired quality of life. Diagnosis of MPE is established through pleural fluid cytology or histopathological confirmation, supported by radiological imaging. Liquid biopsy offers a minimally invasive approach for detecting molecular alterations. Although diagnostic and therapeutic modalities have improved, management remains primarily palliative. Therapeutic thoracentesis, chemical pleurodesis using talc, and indwelling pleural catheter (IPC) placement are the main palliative strategies. Combination therapy of IPC with talc slurry demonstrates higher rates of spontaneous pleurodesis and shorter hospital stays. Systemic therapies such as chemotherapy, targeted therapy, and immunotherapy provide additional disease control in selected patients. Although current approaches have improved diagnostic and therapeutic outcomes, most treatments remain palliative. Therefore, a multidisciplinary and personalized strategy is essential to optimize patient quality of life. This review underscores the importance of early diagnosis and management of malignant pleural effusion, including cytology, pleural biopsy, imaging, and liquid biopsy, as well as therapeutic approaches such as thoracentesis, pleurodesis, indwelling pleural catheter, systemic therapy, and palliative care.
Abses Paru pada COVID-19 Adi Kurniawan; Paramita Khairan; Nurfanida Librianty; Mahrani Mahrani; Hana Faisal; Iffa Mutmainah; Fitriana Nur Rahmawati; Sarah Shafa Marwadhani; Gadistya Novitri Adinda; Uti Nilam Sari; Pukovisa Prawirohardjo
Majalah Kedokteran Indonesia Vol 70 No 8 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.8-2020-255

Abstract

Objective: COVID-19 is a new emerging disease since December 2019 that later was announced by WHO as a global pandemic. Radioimaging appearance of COVID-19 is varied yet dominantly showed as a ground glass appearance in CT-imaging. Lung abscess in COVID-19 is an extremely rare case, therefore it needs further discussion. Method: We report a 39 year-old male patient of COVID-19 with lung abscess.Result: This case report describe a COVID-19 patient who showed a very rare clinical manifestation; lung abscess. The patient showed negative result of TB molecular test. Chest tube insertion procedure was performed in this patient who showed an improvement after abscess being drained. Conclusion: Lung abscess may occur in COVID-19. Abscess drainage procedure may improve clinical condition of COVID-19 patient.
Co-Authors Adi Kurniawan Anna Rozaliyani Aziziah, Aziziah Dea Putri Audina Elhidsi, Mia Faisal Yunus Faisal Yunus Fitriana Nur Rahmawati Fitriana Nur Rahmawati Gadistya Novitri Adinda Gadistya Novitri Adinda Hasyim, Ammar Abdurrahman Herawati Hidajat Iffa Mutmainah Kirana, Widya Tria Kitagawa, Hiroki Librianty, Nurfanida Mahrani Mahrani Mahrani Nastiti Rahajoe Pane, Irene Audrey Davalynn Paramita Khairan Prasenohadi Pukovisa Prawirohardjo Pukovisa Prawiroharjo Sarah Shafa Marwadhani Sarah Shafa Marwadhani Setiawan, Gigih Sita Laksmi Andarini Theresia Rasta Karina Uti Nilam Sari Uti Sari Zaini, Jamal