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All Journal Jurnal Kedokteran Indonesia Preventif Journal Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Aisyah : Jurnal Ilmu Kesehatan Respiratory Science The Avicenna Medical Journal Cermin Dunia Kedokteran

Faisal Yunus

Universitas Indonesia

Author-ID : 425973

Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Korelasi Penilaian Asma Terkontrol Pada Penderita Asma Persisten Sesudah Pemberian Kortikosteroid Inhalasi dengan Menggunakan Asthma Control Scoring System dan Asthma Control Test Widysanto, Allen; Surjanto, Eddy; Suradi, .; Yunus, Faisal
Jurnal Kedokteran Indonesia Vol 1, No 1 (2009)
Publisher : Jurnal Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.434 KB)

Background: The individual parameters to define asthma severity and asthma control overlap significantly. Validated measures, such as ACT, ACS, ACQ, for assessing asthma control are now available, but no comparison among the existing measures has been performed. This study aimed to assess the correlation between ACT and ACS either before of after inhaled corticosteroid ( ICS ).Methods: This was a cohort study. Samples were collected by consecutive sampling. Two asthma control questionnaires, ACS and ACT, must be filled-up by the patients. Spirometry was performed after asthma control questionnaires were completely filled-up. The certain dose of inhaled corticosteroid (ICS ) was given for 2 months, and patients have to repeat the same procedure as they have done after 2 months inhaled corticosteroid administered.Results: The correlation of ACS score based on ACT category score before ICS showed no agreement. In contrary, the correlation of ACS score based on ACT category score after ICS showed significantly moderate agreementConclusion: There was a moderate correlation statistically significant agreement between ACS and ACT assessment when ACS score of 60% was used as the cut off point. Jurnal Kedokteran Indonesia: 1 (1): 56-63Keywords: asthma, persistent, ACS, ACT

HUBUNGAN ANTARA LAMA MEROKOK DAN JUMLAH ROKOK DIHISAP PERHARI DENGAN PPOK (STUDI KASUS: RS PERSAHABATAN JAKARTA) Kolewora, Yusuf Musafir; Ratnawati, Ratnawati; Yunus, Faisal
Preventif Journal Vol 3, No 2 (2019): Preventif Journal
Publisher : Universitas Halu Oleo

ABSTRAKPenyakit Paru Obstruksi Kronik (PPOK) merupakan penyebab utama angka kesakitan dan kematian di seluruhdunia termasuk di Indonesia. Hasil Riset Kesehatan Dasar (RISKESDAS) tahun 2013 menunjukkan bahwaprevalens PPOK di Indonesia sebanyak 3,7% dan menduduki peringkat ke-6 dari 10 penyebab kematian diIndonesia. Penelitian ini merupakan studi awal untuk mengetahui prevalens PPOK di RSUP Persahabatan.Penelitian ini menggunakan desain studi potong lintang dengan metode consecutive sampling pada pasienrawat jalan yang berkunjung di RSUP Persahabatan Jakarta pada bulan April-September 2018. Diagnosis PPOKdilakukan dengan menggunakan COPD Diagnostic Questionnaire (CDQ) dan pemeriksaan spirometri. Hasilpenelitian ini menunjukkan bahwa faktor lama merokok (nilai-p = 0,012) dan jumlah rokok yang dihisap perhari (nilai-p = 0,000) yang berhubungan dengan PPOK.Kata kunci: COPD diagnostic questionnaire, PPOK, spirometri,.

Tatalaksana Tuberkulosis Resistensi Ganda (MDR-TB) pada Anak. Syah Putra Yahya, Wiendo; Agustin, Heidy; Yunus, Faisal; B Setyanto, Darmawan
Cermin Dunia Kedokteran Vol 43, No 5 (2016): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Prevalensi MDR-TB pada anak meningkat cepat dibandingkan dengan dekade sebelumnya. Regimen pengobatan MDR-TB pada anak menggunakan OAT lini kedua yang kurang efektif, lebih banyak efek samping, rasio toksisitas dengan terapeutik yang lebih sempit dan waktu pengobatan yang lebih lama. Pemantauan pasien MDR-TB anak dilakukan secara ketat terhadap gejala klinis, foto toraks, biakan M.tb, sputum BTA dan pemeriksaan darah secara teratur.

The Prevalence of Diabetes Mellitus in Chronic Obstructive Pulmonary Disease Patients Mariska Pangaribuan; Faisal Yunus; Triya Damayanti; Rochsismandoko Rochsismandoko
Jurnal Respirologi Indonesia Vol 40, No 1 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Backgrounds: Type 2 diabetes mellitus (DM) is a common comorbidity of COPD. COPD may be considered as a risk factor for new onset type 2 DM via multiple pathophysiological alterations such as systemic inflammation, smoking, oxidative stress, obesity and inhaled corticosteroid use. Exact prevalence of DM in COPD patients in Indonesia still unclear. Co-morbid conditions like DM have great impact on the outcome of COPD in the form of severity, morbidity and mortality. Methods: A cross sectional study was done in Asthma-COPD clinic Persahabatan Hospital from February to March 2017 to screen COPD patients for DM. Sixty-four subjects were recruited. Interview, physical examination and laboratory testing were performed in all subjects. Results: A total of 64 patients with COPD (Males=60, Female=4) with mean age 65±8.7 were screened for DM. Patients with known history of DM were 12 subjects (18.8%) and were enrolled as known DM cases. Remaining 52 subjects (81.3%) whose DM status was unclear were screened by random or fasting blood sugar and HbA1c. Two subjects (3.1%) were considered as newly diagnosed DM cases. Prevalence of DM in present study was 21.9%. Number of patients with pre-diabetes was 16 subjects (25%). There was no significant relationship between gender, age, smoking, nutritional status, airflow limitation and inhaled corticosteroid use in occurrence of DM among COPD patients. Conclusions: Prevalence of DM in COPD patients in the present study is 21.9%. It is important to screen all COPD patients for DM routinely. (J Respir Indo. 2020; 40(1): 48-57)

Longitudinal Study Of BODE Index As Predictive Factor of COPD In Persahabatan Hospital Jakarta Isep Supriyana; Faisal Yunus; Budhi Antariksa; Aria Kekalih
Jurnal Respirologi Indonesia Vol 39, No 4 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v39i4.75

Background: The BODE index is generally used for predicting mortality risk of COPD patients. The BODE index included the body mass index, degree of airflow obstruction (FEV1), dyspnea (MMRC questionnaire), and exercise capacity (6-minute walk test). Exacerbation of COPD associated with decreased health related quality of life (HRQoL). HRQoL has become an important outcome in respiratory patients as proved by St.George’s Respiratory Questionnaire (SGRQ). This study aim to find the correlation between BODE index with exacerbation and quality of life of COPD patients. We hypothesized that the higher BODE index score, the more frequent exacerbation occurrence and HRQoL decreased. Methods: Prospective cohort study of COPD patients was conducted in Persahabatan Hospital in November 2010 till June 2011. This study assessed the BODE index (at baseline) and followed at 3, 6, 9 and 12 months. Patient were also examined with SGRQ at baseline and followed at 6 and 12 months. We monitored the occurrence of exacerbation every month by telephone, observed their medical record, or visited the COPD’s clinic and emergency departement. Results: Eighty-five patients were examined at baseline with mean of BODE index 4.29 and SGRQ total score 41.42%. After one year follow up 52 patients have completed examination, 29 patients have not complete examination and 4 patients died. Using t-test analysis the correlation of BODE index between single and frequent exacerbation was significant (P

The Correlations Between Measurement of Lung Diffusing Capacity for Carbon Monoxide and The Severity Group of Asthma Patients in Persahabatan Hospital Jakarta Bulkis Natsir; Faisal Yunus; Triya Damayanti
Jurnal Respirologi Indonesia Vol 42, No 1 (2022)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v42i1.296

Introduction: Airway remodeling in asthma which involve small airway can affect until alveoli and cause abnormalities in the lung parenchyma. This study tries to find lung parenchymal abnormalities in patients with asthma through the examination diffusion capacity with a single breath DLCO method.Methods: A cross-sectional study by dividing asthma based on the degree of severity into two major groups, namely mild asthma (intermittent and mild persistent) and severe (persistent moderate and severe). The amount of each group is 31 subjects and 29 subjects, which are taken consecutively from stable asthma patients without comorbid who are seeking treatment in Persahabatan Hospital in December 2015 - May 2016.Results: The average value of DLCO /predictions in mild asthma group is 92,74 ± 15,70% and decreased in the severe asthma group is 77,45 ± 16,78%. Some spirometry value showed significant positive correlation with the value of DLCO/prediction, namely: FVC/prediction, FEV1 /prediction and FEF25-75 % / prediction with p < 0.05. Correlation analysis showed FVC/prediction could dramatically affect the diffusion capacity of asthmatic patients. There is a significant relationship between abnormalities in lung function (p=0,004) and severity of asthma (p=0.000) with a corresponding decrease DLCO / prediction (DLCO/ prediction ≤75 %).Conclusion: The severity of asthma has a relationship with the diffusion capacity of the lungs, increased severity will decrease the diffusion capacity in asthma patients. Decreasing diffusion capacity showed that abnormalities in asthma not only occur in the respiratory tract but also in the lung parenchyma.

Risk Factors Affecting Respiratory Symptoms and Impaired Lung Function of Palm Oil Mill Workers in the District of Kandis Surya Hajar Fitria Dana; Indi Esha; Faisal Yunus; Adrianison Adrianison; Azizman Saad; Ridha Restilla
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.194

Background: Air pollution that exposed to human have been a problem all over the world and caused a variety of lung disease. Gases and particles emitted from industry including sulfur oxide, nitrogen oxide, and particulate matter may lead to decreasing lung function. Sulfur dioxide is one of the highest causes of air pollution at the highest level. Workers exposure to gases were vulnerable to respiratory function abnormality. Methods: A study on the effect of risk factors and sulfur dioxide exposure on lung function of palm oil workers in the district of Kandis was carried out in December 2019–January 2020. The research aim at describing sulfur dioxide air ambient in palm oil mill as well as respiratory state of palm oil workers and analyzing sulfur dioxide exposure and lung function relationship. Result: The result showed that sulfur dioxide concentration in outdoor 25.7 µg/Nm3 and indoor 20.6 µg/Nm3. The result of spirometry showed obstruction in 13% of the workers. Breathlessness and productive cough are the most common symptoms. Several factors that correlated with lung function namely as personal protective equipment (p=0.001), length of working (p=0.003), and smoking habit (p=0.004). From multivariate analysis, personal protective equipment has a significant correlation with lung function (p=0.038). Conclusion: Increasing the concentration of sulfur dioxide may cause decreased of lung function but other factor like personal protective equipment showed a significant correlation with lung function.

Proportion of Patients Pulmonary Cancer With History of Slow Diagnosis Due to Diagnosis as Lung Tuberculosis Cut Yulia Indah Sari; Faisal Yunus; Elisna Sjahruddin
Jurnal Respirologi Indonesia Vol 39, No 2 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Background: In tuberculosis (TB) endemic countries, the diagnosis delay in lung cancer is due to initially misdiagnosed as pulmonary tuberculosis. The major concern that rose since early diagnosis of lung cancer could improve survival by tumor resectability chance and chemo-radiotherapy modality options. This study objective was to find out the proportion of lung cancer diagnosis delay due initially to misdiagnosed as pulmonary TB. Method: The cross-sectional study was held in Persahabatan Hospital and the subjects were histopatologically proven lung cancer patients between September 2012 to February 2013 involving totally 100 patients. The diagnosis delay were determined as whether the patients had been diagnosed as pulmonary tuberculosis and received anti-tuberculosis treatment (ATT) more than one month since current symptoms onset. All patients were interviewed and all chest X-rays were documented. Results: Fourty one of 100 patients were diagnosed as pulmonary TB and 29 of 41 patients received ATT more than one month. It consisted of 21 men and 8 women with the mean age of 51.5 years old. The cytology and histopatological biopsy revealed 28 Non Small Cell Lung Cancer (NSCLC) cases, and One Small Cell Lung Cancer (SCLC) case with all case were in end stage condition (6 cases in stage III and 22 cases in stage IV). Pre-referral sputum Acid Fast Bacilli (AFB) was conducted in only 9 cases with all negative results. Mean duration of ATT taken was 4.5±0.4 months. The ATT were given by 13 general practitioners, 12 pulmonologists and 4 internists. Discussion: Similar radiological findings in highly incidence of pulmonary TB could cause a large number of diagnosis delay in lung cancer due to initially diagnosed as pulmonary tuberculosis. Without proper investigation based on International Standard of TB Care, starting ATT with inadequate evaluation leads to diagnosis delay and lung cancer progression. (J Respir Indo 2019; 39(2): 92-102)

Lung Diffusion Capacity of X Fighter Pilot in Madiun Ririn Astuty Ningsih; Faisal Yunus; Triya Damayanti; Flora Ekasari; Sita Laksmi Andarini; Dicky Soehardiman; Ratnawati Ratnawati; Fathiyah Isbaniah; Erlang Samoedro
Jurnal Respirologi Indonesia Vol 40, No 1 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Background: Pilot works in the high environment that exposed by G force. Increasing G force led to linear decreases in cardiac output and blood oxygenation of the brain. Thus, likely due to decreased lung gas exchange capacity in hypergravity. This study aims to investigate the pulmonary diffusing capacity test among Fighter pilots in Madiun. Methods: This study used cross sectional method conducted on February 2019 in Madiun. The total subjects consist of 44 Fighter pilots based on total sampling. Interview was done to fill out question about sociodemografic and smoking habit, flight hour data and physical fitness. Lung function measurement was done using portable spirometry and DLCO equipment (Easyone TM Pro Lab). Result: Spirometri result was found in the standard normal range in 41 subjects (93,2%) only 3 subject (6,8%) get obstruction abnormalities and none of them get restriction result. Average VEP1 prediction was 103,3±10,60 % and median range for VEP1/KVP was 84,5(63,5-92,5) %. Lung diffusion capacity measurement was found to be normal in 41 subject (93,2%) and to be deficient in 3 subject (6,8%) in smoker. Conclusion: This study demosntrated that diffusion capacity and spirometry test in Fighter pilots generally in normal range. Lung diffusion capacity has no association with age, BMI, flight hour, physical fitness, Brinkman index and spirometry parameters. (J Respir Indo. 2020; 40(1): 39-47)

Lung Function and Respiratory Symptoms of Petrol Station Attendants in Central and North Jakarta and Its Contributing Factors Putri Suci Ramadhany; Faisal Yunus; Agus Dwi Susanto
Respiratory Science Vol. 1 No. 1 (2020): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v1i1.7

Background: To satisfy growing needs of petrol consumption in big city many new petrol stations has been built. Petrol station attendant is considered to have high risk exposure to dangerous pollutant from motor vehicle emission and petrol fumes, especially while filling up petrol tanks. Combination of those exhaust and petrol fumes is suspected to cause the reduction of lung function. Methods: This research is a cross sectional study in petrol station in Central Jakarta and North Jakarta region between August 2017 and February 2018. A total of 97 petrol station attendants were taken in this research using consecutive sampling technique. The subjects were interviewed with questionnaires, spirometry and chest radiograph. Measurements of sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), ozone (O3), particulate matter 2,5 (PM 2,5) and steam gasoline (benzene) concentrations were performed at the study sites. Results: In this study, 56.7% normal spirometry results, 42.3% abnormalities in the form of restriction, 1% obstruction and none of which experienced mixed disorders of restriction and obstruction. Most subjects (84.6%) did not experience respiratory complaints, 10.3% had a dry cough and 5.1% complained of cough with phlegm. There was a statistically significant association between peak expiratory flow and duration of work (p=0.011), but no significant association with other parameters such as forced vital capacity (FVC), %FVC, forced expiratory volume in the first second (FEV1), %FEV1 and the ratio of FEV1/FVC. Conclusion: Prevalence of lung function abnormalities of petrol station attendant is 43,3% and respiratory symptoms at 15,4% subject.

Co-Authors . Suradi Adang Bachtiar Adityo Wibowo, Adityo Adrianison Adrianison Adrianison, Adrianison Agus D. Susanto Agus Dwi Susanto Agustin, Heidy Allen Widysanto Amien, Bagus Radityo Amira P Tarigan, Amira P Angela BM Tulaar Anita Ratnawati Antalia K.M. Katili Antono, Wahyu Anwar Jusuf Aria Kekalih Arifin Nawas Arifin, Arief Riadi Aryana, Wayan Ferly Astari Pranindya Sari Azizman Saad B Setyanto, Darmawan Barmawi Hisyam Basalamah, Muhammad Abbas Brahmantyo, Adhimas Budhi Antariksa Bulkis Natsir Cut Yulia Indah Sari Damayanti, Triya Dewantoro, Luhur Dwi Handoko Eddy Surjanto Ekawati, Diyan Elhidsi, Mia Elisna Sjahruddin Endang Purwaningsih Esha, Indi Fachrucha, Fanny Faisal, Hana Khairina Putri Fariz, Nurwidya Febrihartati, Isura Flora Ekasari Gozali, Achmad Gurning, Andi Sarikawan Hadiarto Mangunnegoro Hana Khairina Putri Faisal Harahap, Makrup E Helena Turnip Idrus Alwi Indi Esha INDRA YOVI Indriani, Sri Indah Isbaniah, Fathiyah Isep Supriyana Joko Riyadi Jordy Oktobiannobel Kirana, Widya Tria Kitagawa, Hiroki Kolewora, Yusuf Musafir Laras, Sekar Lientje S. Maurits, Lientje S. Lindra, Derallah A Listiandoko, Raden Dicky Wirawan Marisa Afifudin Mariska Pangaribuan Meirissa, Tria Menaldi Rasmin Moelamsyah, Yandi Noer Mohammad Farid Neni Sawitri Nury Nusdwinuringtyas Patrama, Satria Pinaka Baladika, Dimas Trend Putra, Muhammad Ryan Adi Putri Suci Ramadhany Putri, Maharani Ratnawati Antaria Ratnawati Ratnawati Ratnawati Ratnawati Ridha Restilla Ririn Astuty Ningsih Risa Febriana Rochsismandoko Rochsismandoko Rochsismandoko Rochsismandoko Roxanne, Olivia Geraldine Sabarina Prasetyo Samoedro, Erlang Saroyo, Yudianto Budi Setiawan, Gigih Sinaga, Fransisca TY Sita Laksmi Andarini Soehardiman, Dicky Soemarwoto, Retno Ariza Soeprihatini Soemarwoto, Retno Ariza Soerjanto Soerjanto Sri Melati Munir Suradi Suradi Surya Hajar Fitria Dana Suwarno, Sukarti San Syafruddin A.R. Lelosutan Syah Putra Yahya, Wiendo Syazili Mustofa Tamsil Syafiuddin, Tamsil Triya Damayanti Utomo, Ahmad Rusdan H Wahju Aniwidyaningsih Wicaksono, Muhammad Bimo Adi Widjajalaksmi Widjajalaksmi Widjanantie, Siti Chandra Wiwien H. Wiyono Wiwien Heru Wiyono Yulino Amrie Zaini, Jamal Zarfiardy Aksa Fauzi Zulhadji, Harry Agustio Zulkarnain Barasila

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