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Hubungan Kepadatan Tumor-Associated-Macrophages dan TumorAssociated-Neutrophils dengan Karakteristik Klinikohistopatologi pada Pasien Limfoma Hodgkin Nadya Virana Putri; Neti; Riana Sari Puspita Rasyid; Krisna Murti
Majalah Patologi Indonesia Vol 30 No 2 (2021): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Indonesia (IAPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (457.287 KB) | DOI: 10.55816/mpi.v30i2.471

Abstract

BackgroundThe development and aggressiveness of tumor cells were influenced by tumor microenvironment. Tumor-Associated-Macrophages(TAMs) and Tumor-Associated-Neutrophils (TANs) are components of tumor microenvironment, contribute to development and growthof tumor cells. The aim of this research was to analyse correlation of TAMs and TANs densities with clinicohistopathologiccharacteristics of patients i.e. age, gender, location, and subtype.MethodsA case series was conducted. The samples were paraffin blocks of Hodgkin lymphoma patients at Anatomic Pathology DepartmentFaculty of Medicine Universitas Sriwijaya/RSUP Dr. Mohammad Hoesin Palembang. Among 44 cases of Hodgkin lymphomadiagnosed from 1stJanuari 2015 to 30th October 2019, only 31 cases were included. Immunohistochemistry was performed by usinganti-CD163 antibody and neutrophils were identified by morphologic appearances. The results were correlated to characteristicfactors. Statistical analysis was performed using Spearman and Lambda test with significant consideration if p<0.05.ResultsThe study results showed 30 cases of classical Hodgkin lymphoma (CHL) and 1 case of NLPHL. CHL has only 3 variants LR(lymphocyte-rich) (60%), MC (mixed-cellularity) (26.7%), and NS (nodular sclerosis) (13.3%). Hodgkin lymphoma is most commonlyfound in males (61.3%). Tumor were mostly found in the head and neck, and patient ages were majority in the age group 20-29 years,40-49 years, and over 50 years. Spearman test showed there was a significant correlation between density of TAMs with ages(p=0.043).ConclusionHigh density of TAM was correlated with age, however, there was no correlation between TAN and clinicohistopathologiccharacteristics of Hodgkin lymphoma.
DIVERSITY AND BIOMASS POTENTIAL OF UNDERWATER PLANTS AMPUPU PLANTATION FOREST (Eucalyptus urophylla) IN TOKOLULI, RAILAKO DISTRICT ERMERA MUNICIPALITY, TIMOR-LESTE Leopoldino V. Martins; Mohammad Ali Mahmudi; Neti; Abdul Mukti; Muhammad Rizky Pratama
Jurnal Cakrawala Akademika Vol. 2 No. 1 (2025): Edisi Juni 2025
Publisher : PT. Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70182/jca.v2i1.788

Abstract

The objective of this study is to determine the composition and diversity of vegetation in the forest planted in Ampupu and determine the biomass and carbon storage of vegetation in the village of Tokoluli, district of Railako, Ermera regency. The population in this study is composed of all types of undergrowth found under teak stands in the village of Tokoluli, Railako district, Ermera regency. The samples in this study are all types of undergrowth contained in the plot or observation plot. The results of the research obtained the highest value of the density parameter from the results of the analysis, the iber, Langur feathers (Rubiaceae) with a total density of 8.466 Ha individual, For the highest relative density value was found in langur feathers (Rubiaceae) of 423.33%, the highest frequency value of all types of subplant plants,     namely langur feathers (Rubiaceae) with a value of 8.47, a high important value index shows that the species has the largest number of individuals, the density and frequency of its species found in the community are also high of the 29 species identified, there are several types of undergrowth that have the highest NPI, including langur feathers (Rubiaceae) of 846.7 and caterpillar (Brachiaria decumbens) 193.3, From the results of the analysis of the data, specimens with the highest value of SDR are of the property of the female (Mimosa pudica) 98% and of the Tembelekan (Lantana chambera Linn.) At 98.9%.  Some of the types that are also the most valuable SDRs after Tembelekan and Putri Malu with 86.7%, Grass Teki with 83.3% and Alang-Alang with 63.3%. Meanwhile, the species that have the lowest SDR values are Bitter Grass and Manon with 90% and 30%, respectively. The total value of H' de vegetation rasteira en forestestas protegidas na vila de Railako, municipal town of Gleno, is 3153.