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All Journal Universa Medicina Jurnal Pengabdian Masyarakat: Humanity and Medicine CRJIM (Clinical and Research Journal in Internal Medicine)
Permata, Mega
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Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Edukasi penyakit HIV pada masyarakat di Kelurahan Sukamaju, Palembang, Sumatera Selatan Hudari, Harun; Aprilia Salim, Nelda; Fathurrachman, Alif; Permata, Mega
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 5 No 3 (2024): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V5I3.147

Abstract

. Human Immunodeficiency Virus (HIV) is a disease caused by the HIV virus and transmitted through sexual contact. The spread of HIV in the community continues to occur. Palembang is the highest city in South Sumatra for HIV cases. From January to July 2022, there were 185 HIV cases in Palembang. Many people still do not know about HIV disease and its transmission. There is a lot of confusing news about HIV disease, which can lead to misunderstanding in the community. Good and appropriate education can be a means for people to understand the dangers and transmission. Therefore, it is necessary to increase public knowledge about HIV and its transmission, in order to reduce the incidence of HIV disease and avoid the risk of transmission in the community. Through community service activities by educating the community about HIV, which is done with material presentations and face-to-face meetings and discussions. Measuring the level of knowledge of participants through questionnaires before and after counseling, an increase in understanding of HIV was obtained, with a mean score before 45, and a mean score after 85. This activity increases the understanding score of the prevention and transmission of HIV disease.
Correlation Between Serum Testosterone Levels and CD4 T Lymphocyte Counts in Naive HIV-Infected Men at dr. Mohammad Hoesin General Hospital Palembang Fahrenheit, Fahrenheit; Kusnadi, Yulianto; Hudari, Harun; Bahar, Erial; Shahab, Alwi; Anggraini, Ratna Maila Dewi; Permata, Mega; Salim, Nelda Aprilia; Yuniza; Bakrie, Muhammad
Clinical and Research Journal in Internal Medicine Vol. 6 No. 2 (2025): Volume 6 No 2, November 2025
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2025.006.02.07

Abstract

Background: HIV infection often leads to endocrine complications, including hypogonadism which characterized by low serum testosterone, potentially affects quality of life and contributes to metabolic issues, such as muscle weakness, depression, osteoporosis, and cardiovascular disease. Some studies have indicated a connection between testosterone levels and CD4 T lymphocyte counts.   Aim: To evaluate the correlation between total serum testosterone levels and CD4 T lymphocyte counts in naive HIV-infected men. Methods: A cross-sectional analitycal study was conducted at Dr. Mohammad Hoesin General Hospital, Palembang, from April to October 2024. Involving 64 naive HIV-infected men. Total serum testosterone and CD4 T cell counts were measured and analyzed. Results: Participants mean age is 36.52 ± 11.03 years with BMI of 19.52 ± 3.71 kg/m². Most subject (62.5%) are reported men who had sex with other men. Poor sleep quality was found in 81%, mild depressive symptoms in 38.1%, and mild erectile dysfunction in 28.6%. Hypogonadism occurred in 32.8% of subjects (28.1% secondary and 4.7% primary). Mean number of testosterone level was 446.75 ± 260.95 ng/dL, with a median CD4 count of 23.5 cells/µL. A significant positive correlation was observed between testosterone levels and CD4 counts (r = 0.313; p = 0.012) although testosterone levels did not significantly differ across HIV clinical stages (p = 0.464). Conclusion: There is a significant positive correlation between serum testosterone levels and CD4 T lymphocyte counts in naive HIV-infected men. Hormonal disturbances may arise in early infection. Hence, testosterone assessment is recommended during the initial evaluation on HIV patients.
Higher uric acid serum levels are associated with sarcopenia among elderly in a community health center Farista, A. Deza; Rivianti, Nur; Bahar, Erial; Permata, Mega; Reagan, Muhammad; Indah, Crisnah; Artini, Ika
Universa Medicina Vol. 44 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2025.v44.335-344

Abstract

BackgroundAs people age, skeletal muscle mass and strength decrease, leading to sarcopenia, diagnosed through calf circumference, muscle mass, strength, and physical performance. Uric acid (UA), with both pro-oxidant and antioxidant properties, is an indicator of oxidative stress and may contribute to sarcopenia. This study aimed to determine the correlation between serum uric acid levels and sarcopenia in elderly in a community health center. MethodsA cross-sectional study was conducted involving 42 subjects aged ≥60 years, consisting of 37 female and 5 male participants. We applied Asian Working Group for Sarcopenia (AWGS) 2019 criteria to define sarcopenia. Muscle mass was measured using skeletal muscle index (SMI) based on bioimpedance analysis (BIA). Handgrip strength (HGS), physical performance, calf circumference, and blood test data were collected. A backward regression analysis was performed to investigate the relationship between UA and SMI, HGS, physical performance, and calf circumference after adjusting for gender, smoking history, upper arm circumference, and body mass index.Results After adjusting for potential confounding variables, uric acid remained significantly associated with muscle strength (β=0.326; p=0.023) and calf circumference (β=0.264; p=0.010), but not with muscle mass (β=0.046; p=0.727) or physical performance (β=–0.171; p=0.279).ConclusionThere is a significant correlation between uric acid levels and muscle strength, physical performance, and calf circumference in sarcopenia among the elderly in the community health center. Higher uric acid serum levels might slow down the progression of sarcopenia.
Co-Authors Anggraini, Ratna Maila Dewi Aprilia Salim, Nelda Artini, Ika Bakrie, Muhammad Erial Bahar, Erial Fahrenheit, Fahrenheit Farista, A. Deza Fathurrachman, Alif Hudari, Harun Indah, Crisnah Muhammad Reagan Nelda Aprilia Salim Rivianti, Nur Shahab, Alwi Yulianto kusnadi Yuniza