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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Cendekia Medika : Jurnal Stikes Al-Ma`arif Baturaja Bioscientia Medicina : Journal of Biomedicine and Translational Research
Thia Prameswarie
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Hematologic profiles of Plasmodium vivax Malaria patients Gita Dwi Prasasty; Thia Prameswarie; Muhaimin Ramdja; Dwi Handayani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 2 No. 2 (2018): Bioscientia Medicina: Journal of Biomedicine and Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v2i2.44

Abstract

Abstract Background: Malaria infections cause various symptoms ranging from asymptomatic infections to severe disease complications. Plasmodium vivax malaria has been recognized as a disease that attacks blood cells, causing various hematologic changes, especially anemia, leukopenia, leukocytosis, neutropenia, neutrophilia, and thrombocytopenia with different percentages. Plasmodium vivax, formerly known to cause mild malaria, was later proven to cause severe malaria, even cerebral malaria such as Plasmodium falciparum. This study aims to determine the hematologic profile in patients with Plasmodium vivax malaria. Method: This research use descriptive cross sectional design. This research was conducted in Puskesmas (PKM; Primary Health Care) Sukamaju and Puskesmas (PKM; Primary Health Care) Karang City in August until December 2017. Samples were taken by consecutive sampling. A total of 37 samples expressed positive Plasmodium vivax, examined their hematologic profiles specifically hemoglobin, erythrocytes, leucocytes, platelets, lymphocytes, neutrophils, monocytes and hematocrit using automatic hematology cell counter. Results: Based on the results of this study, 56.76% of patients had anemia, 45.90% of patients had leukopenia, 89.20% thrombocytopenia, 2.70% neutrophilia, 10.80% neutropenia, 2.70% lymphocytosis, 35.10% lymphopenia, and 13.50% pancytopenia. Conclusion: In patients with Plasmodium vivax malaria infection there may be a change in hematologic profiles, this change may be affected by the acute phase of infection and host immune system. Keywords: Plasmodium vivax malaria, hematologic profiles
Hematologic profiles of Plasmodium vivax Malaria patients Gita Dwi Prasasty; Thia Prameswarie; Muhaimin Ramdja; Dwi Handayani
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 2 No. 2 (2018): Bioscientia Medicina: Journal of Biomedicine and Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v2i2.44

Abstract

Abstract Background: Malaria infections cause various symptoms ranging from asymptomatic infections to severe disease complications. Plasmodium vivax malaria has been recognized as a disease that attacks blood cells, causing various hematologic changes, especially anemia, leukopenia, leukocytosis, neutropenia, neutrophilia, and thrombocytopenia with different percentages. Plasmodium vivax, formerly known to cause mild malaria, was later proven to cause severe malaria, even cerebral malaria such as Plasmodium falciparum. This study aims to determine the hematologic profile in patients with Plasmodium vivax malaria. Method: This research use descriptive cross sectional design. This research was conducted in Puskesmas (PKM; Primary Health Care) Sukamaju and Puskesmas (PKM; Primary Health Care) Karang City in August until December 2017. Samples were taken by consecutive sampling. A total of 37 samples expressed positive Plasmodium vivax, examined their hematologic profiles specifically hemoglobin, erythrocytes, leucocytes, platelets, lymphocytes, neutrophils, monocytes and hematocrit using automatic hematology cell counter. Results: Based on the results of this study, 56.76% of patients had anemia, 45.90% of patients had leukopenia, 89.20% thrombocytopenia, 2.70% neutrophilia, 10.80% neutropenia, 2.70% lymphocytosis, 35.10% lymphopenia, and 13.50% pancytopenia. Conclusion: In patients with Plasmodium vivax malaria infection there may be a change in hematologic profiles, this change may be affected by the acute phase of infection and host immune system. Keywords: Plasmodium vivax malaria, hematologic profiles
MULTIBACILLARY LEPROSY IN TWO ADULT PATIENTS: A CASE REPORT WITH PERIPHERAL NERVE INVOLVEMENT Rilliani Hastuti; Indri Widya Sari; Nurita Bangun Hutahean; Lilis Khairani; Ghiffari, Ahmad; Thia Prameswarie
Cendekia Medika: Jurnal Stikes Al-Ma`arif Baturaja Vol. 11 No. 2 (2026): April - June
Publisher : LPPM STIKES Al-Ma'arif Baturaja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52235/cendekiamedika.v11i2.748

Abstract

Multibacillary leprosy remains a significant public health issue due to its potential to cause progressive nerve damage, disability, and ongoing transmission if not detected and treated early. This case report highlights two cases that underscore key lessons in leprosy management. In Case 1, despite the patient completing multidrug therapy (MDT) and being declared cured, the re-emergence of skin lesions raised the possibility of relapse, reinfection, or leprosy reaction, emphasizing the importance of post-MDT follow-up for patients. Meanwhile, Case 2 illustrates the need for early detection of peripheral neuropathy in patients with neuropathic ulcers without pain, leading to the loss of protective sensation. Peripheral nerve involvement in both cases underscores the need for thorough neurological evaluation to prevent permanent disability. The specific clinical lesson is that in-depth neurological evaluation and continuous post-MDT monitoring are crucial for preventing nerve complications and early relapse detection, thereby improving patient quality of life.
Co-Authors Ahmad Ghiffari Dwi Handayani Gita Dwi Prasasty Indri Widya Sari Lilis Khairani Muhaimin Ramdja Nurita Bangun Hutahean Rilliani Hastuti