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Alam, Ilham Putera
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Religion Humanities Health Professions Medicine & Pharmacology Public Health Social Sciences

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Intracerebral Hemorrhage-Grading Scale (ICH-GS) Score as a Prognosis Prediction of Spontaneous Intracerebral Hemorrhage at Rumah Sakit Islam Surabaya Jemursari Aulia, Nurlisa Naila; Syifak, Shobihatus; Yuniati, Dyah; Alam, Ilham Putera; Surya, Prima Ardiansyah
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4153

Abstract

Background: Spontaneous intracerebral hemorrhage or hemorrhagic stroke is one of the leading causes of mortality and disability in Indonesia, but until now there is no specific therapy for this disease. The intracerebral hemorrhage (ICH) score is a widely used predictive tool for the prognosis of death 30 days after spontaneous intracerebral hemorrhage, but the intracerebral hemorrhage-grading scale (ICH-GS) score has a more specific interval to assess the prediction of the prognosis after intracerebral hemorrhage. Rumah Sakit Islam (RSI) Jemursari Surabaya has not carried out data collection related to the ICH-GS score with the outcome (death) of patients with spontaneous intracerebral hemorrhage, especially while still receiving hospital treatment. Objective: To identify the number of ICH-GS scores in patients with spontaneous intracerebral hemorrhage as a predictor of prognosis at RSI Jemursari Surabaya. Method: The type of this research is retrospective research. The population comprised of all patients with spontaneous intracerebral hemorrhage hospitalized at RSI Jemursari Surabaya in 2017-2019, with affordable population of all patients with spontaneous intracerebral hemorrhage diagnosed by a neurologist. Results: The data showed that 5.5% (6 people) had an ICH-GS score of 5; 38.2% (42 people) had an ICG-GS score of 6; 21.8% (24 people) had an ICH-GS score of 7; 20 % (22 people) had an ICH-GS score of 8; 5.5% (6 people) had an ICH-GS score of 9; 4.5% (5 people) had an ICH-GS score of 10; 3.6% (4 people) had an ICH-GS score of 11; and 0.9% (1 patient) had an ICH-GS score of 12. Conclusions: The results of the ICH-GS score can be used to facilitate communication both with fellow health workers and with the patient's family. Trend of the data showed that ICH-GS score is not consistent in showing the prognosis of spontaneous intracerebral hemorrhage (the smaller the ICH-GS score should have better prognosis than the higher score), while the information based only on volume and location can predict the prognosis more consistently`.
Antidepressant Effects of Mitragyna Speciosa Korth Extract on Diabetic Rats Putra, Reza Hery Mahendra; Awwaliyah, Evi Sylvia; Salim, Hotimah Masdan; Alam, Ilham Putera; Rofiq, Ainul
Jurnal Ilmu Kesehatan dan Kesehatan Vol 8 No 02 (2024): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v8i02.5919

Abstract

Background: Diabetes mellitus is most common associated with neurological complications, including depressive symptoms, so this study investigated whether mitragyna may provide benefits in reducing depressive symptoms in animal models of diabetes. This study aims to evaluate the effect of mitragyna as a potential antidepressant agent in animal models of diabetes mellitus using the Force Swimming Test (FST). Methods: In this study, diabetes mellitus rats were induced by administering streptozotocin and then divided into four groups: control group (Control), Group Diabetes (DM), Mitragyna treatment group (DM+EMS 15mg) and (DM+EMS 30mg). After the treatment period, the rats were then tested with the FST, which is used to measure immobility behavior which can be used as an indicator of depressive symptoms. Results: The results showed that the treatment group that received mitragyna showed shorter immobility times compared to the control group (P<0.01), indicating an increased active response in facing FST stressors. Conclusion: These results indicate that mitragyna has potential as an antidepressant agent in reducing depressive symptoms in rats models of diabetes mellitus.
Co-Authors Aulia, Nurlisa Naila Awwaliyah, Evi Sylvia Putra, Reza Hery Mahendra rofiq, ainul Salim, Hotimah Masdan Surya, Prima Ardiansyah Syifak, Shobihatus Yuniati, Dyah