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All Journal Global Medical and Health Communication Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Indonesian Journal of Cancer
Agustina, Amilya
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Relationship Between C-Reactive Protein-Albumin Ratio and Metastasis in Breast Cancer Hazmi, Mohammad Zul; Panigoro, Sonar Soni; Yulian, Erwin Danil; Nugroho, Nyityasmono Tri; Agustina, Amilya
Indonesian Journal of Cancer Vol 19, No 1 (2025): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i1.1224

Abstract

Background: Breast cancer is a type of malignancy with the highest number of cases in the world and Indonesia. The C-reactive protein-albumin ratio (RCA) is a simple, feasible, and objective breast cancer serum marker representing inflammatory and nutritional status. There are not many studies regarding the relationship between RCA and breast cancer metastasis, especially in the advanced-stage case population in Indonesia.Method: Study with a cross-sectional design in 180 breast cancer patients stage III and IV at Cipto Mangunkusumo Hospital, who were diagnosed in 2018 until 2023. Comparative analysis of the RCA values between the groups with and without metastasis was carried out using the Chisquare test. All statistical test results are considered significant if the p-value is 0.05.Results: A receiver-operating characteristic curve (ROC) is a graphical analytical technique used to assess the effectiveness of a binary diagnostic classification method. The ROC area under the curve (AUC) value was 0.713 (IC 95%; 0.638–0.789) and significance 0.001, with the RCA cut-off value was 0.515 with sensitivity 74.4% and specificity 67.8%. The high RCA proportion was 53.3%. There is a significant relationship (p-value 0,001) between RCA level and the risk of metastasis in breast cancer patients. Liver and lung metastases of breast cancer are the most frequent locations. Conclusion: The CRP-albumin ratio has a significant relationship with the incidence of metastasis in breast cancer
Effect of Structured Workers Physical Exercise, Individual Factors, and Work-related Factors on Physical Fitness of Security Officers Rosady, Dony Septriana; Mirtha, Listya Tresnanti; Agustina, Amilya; Soemarko, Dewi Sumaryani; Sugiharto, Agus
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.13722

Abstract

Security officers require good physical fitness to perform their duties effectively. Maintaining this level of fitness often involves structured exercise programs that consider the frequency, intensity, duration, and type of activity. This study aims to examine the relationship between a structured physical exercise program, individual factors, and work-related factors on the physical fitness of security officers. This study was conducted in July 2023 and utilized company program data from March to June 2023, focusing on 67 security officers at PT X. Physical fitness data was collected using the Cooper test method and analyzed using SPSS. Data normality was assessed using the skewness/standard error method, with values <2 considered normally distributed. A paired sample t-test revealed a significant relationship between Cooper test distances before and after participation in the structured exercise program (p<0.001). Further analysis demonstrated relationships between changes in physical fitness and several factors: work fatigue (p<0.001), work stress dimensions (specifically work overload, role conflict, quantitative and qualitative workload excess, career development, and responsibility to others, all with p<0.014), and sleep quality (p<0.001). The coefficient of determination (r2) was 0.496, indicating that work fatigue, role conflict, and sleep quality collectively explain 49.6% of the variance in physical fitness changes. The remaining variance is likely influenced by factors not included in the model. Multivariate analysis confirmed that work fatigue (p<0.001), role conflict (p=0.036), and sleep quality (p=0.015) were predictors of changes in physical fitness. In conclusion, a structured physical exercise program has a positive influence on the physical fitness of security officers. Furthermore, work fatigue, work stress (particularly role conflict), and sleep quality are associated with changes in physical fitness among these officers.
Upaya Pengelolaan Fatigue Pada Penerbang Dengan Aktivitas Fisik, Latihan Fisik Dan Waktu Tidur Wibawanti, Retno; Agustina, Amilya; Muda, Maria Melania; Werdhani, Retno Asti
Majalah Kedokteran Indonesia Vol 69 No 12 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, V
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.12-2019-169

Abstract

Fatigue is defined as a physiological state of reduced mental or physical performance capability resulting from sleep loss or extended wakefulness, circadian phase, or workload (mental and/or physical activity) that can impair a crew member’s alertness and ability to safely operate an aircraft or perform safety-related duties. An aircraft incident or accident may arise as a result of an error at an individual level (aviator or other crew), where fatigue is one of the main contributing factors.The International Civil Aviation Organization (ICAO) has recommended Fatigue Risk Management System (FRMS) to its member States, including Indonesia. This FRMS is a monitoring system and risk factors management related to fatigue-based burnout, which is carried out continuously. In Indonesia, there are currently few airlines that implement FRMS. It takes practical steps to manage fatigue risk factors in the aviator, especially concerning physical activity, activity in leisure or resting time and time management Sleep.A practical guideline of Fatigue Management for aviators with physical activity, physical exercise and sleeping arrangement is targeted to become a reference to the Fatigue management for pilots, airline management and can be a recommendation for policy stakeholders to become part of the flight safety procedures in Indonesia.
Co-Authors Agus Sugiharto Dewi Sumaryani Soemarko Hazmi, Mohammad Zul Listya Tresnanti Mirtha, Listya Tresnanti Muda, Maria Melania Nugroho, Nyityasmono Tri Retno Asti Werdhani Retno Wibawanti Rosady, Dony Septriana Sonar Soni Panigoro Yulian, Erwin Danil