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Buschke-Lowenstein tumour (BLT)/giant condyloma acuminatum (GCA): an immunopathogenesis insight Christopher, Paulus Mario; Kosim, Hartono; Wijaya, Ratna Sari; Suhardi, Silvi; Wijayadi, Linda Julianti
Bali Dermatology and Venereology Journal Vol 3, No 1 (2020)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v%vi%i.27

Abstract

Buschke Lowenstein tumor (BLT)/giant condyloma acuminatum is a rare variant of a sexually transmitted infection caused by human papillomavirus (HPV) type 6 and 11. HPV has its viral factors that exist to avoid immune surveillance and control through 1) infecting only the basal layer of the epithelium, 2) downregulation of host immunity, 3) suppression of proinflammatory proteins essential for viral clearance. The incidence of BLT/GCA is estimated to be 0.1% in the general population, with males having 2.7 times increased risk than females. A BLT/GCA is characterized by verrucous tumor or palpable cauliflower-likemass, exophytic growth, flesh-colored, and uneven surface. The definitive diagnosis of BLT/GCA is typical morphology along with histopathological examination, and/or viral serotyping. Treatment of BLT/GCA requires a multidisciplinary approach, determined based on age, the extent of the lesion, organ involvement, and organ location.
The Relationship Between Big Five Personality Traits and Academic Performance of Asian Medical Students Lauren, Stefani; Nathania, Jocelyn; Wijayanto, Rhendy; Wijaya, Ratna Sari
Medicinus Vol. 14 No. 1 (2024): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v14i1.9198

Abstract

Introduction : Personality traits have been shown to influence the individual’s critical thinking, learning strategies, and motivation, resulting in the overall student’s academic performance. Academic performance is an important factor among medical students to ensure their success in long-term medical education, training and work performance as medical doctors. This study aims to evaluate the relationship between personality traits and academic performance among medical students. Methods : The study was conducted among preclinical medical students from the Medical Schools of Pelita Harapan University, Indonesia. The personality traits were assessed using the NEO Five-Factor Inventory-3 (NEO-FFI-3), which consists of 60 items assessing the five personality traits (neuroticism, extraversion, openness, agreeableness, and conscientiousness). The academic performance was evaluated using the cumulative grade point average (CGPA) score. Results : A total of 224 participants were included in this study. The mean age of the participants was 19.8 years old (SD±1.3). Neuroticism was the predominant personality trait among medical students and was found to be negatively associated with CGPA in univariable and multivariable analyses (p<0.05). Conclusion : This study reveals that neuroticism personality traits are prevalent among preclinical medical students and adversely affect their academic performance. Understanding the general personality traits present among medical students and its relationship with academic performance can provide valuable input for further medical education programme development.