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All Journal Bali Dermatology and Venereology Journal PAEDAGOGY : Jurnal Ilmu Pendidikan dan Psikologi HEALTHY: Jurnal Inovasi Riset Ilmu Kesehatan
Kosim, Hartono
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Biochemistry, Genetics & Molecular Biology Languange, Linguistic, Communication & Media Medicine & Pharmacology Social Sciences Other

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Buschke-Lowenstein tumour (BLT)/giant condyloma acuminatum (GCA): an immunopathogenesis insight Christopher, Paulus Mario; Kosim, Hartono; Wijaya, Ratna Sari; Suhardi, Silvi; Wijayadi, Linda Julianti
Bali Dermatology and Venereology Journal Vol 3, No 1 (2020)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v%vi%i.27

Abstract

Buschke Lowenstein tumor (BLT)/giant condyloma acuminatum is a rare variant of a sexually transmitted infection caused by human papillomavirus (HPV) type 6 and 11. HPV has its viral factors that exist to avoid immune surveillance and control through 1) infecting only the basal layer of the epithelium, 2) downregulation of host immunity, 3) suppression of proinflammatory proteins essential for viral clearance. The incidence of BLT/GCA is estimated to be 0.1% in the general population, with males having 2.7 times increased risk than females. A BLT/GCA is characterized by verrucous tumor or palpable cauliflower-likemass, exophytic growth, flesh-colored, and uneven surface. The definitive diagnosis of BLT/GCA is typical morphology along with histopathological examination, and/or viral serotyping. Treatment of BLT/GCA requires a multidisciplinary approach, determined based on age, the extent of the lesion, organ involvement, and organ location.
Update on scrofuloderma Marianto, Marianto; Kosim, Hartono; Agung Mahariski, Pande; Christopher, Paulus Mario
Bali Dermatology and Venereology Journal Vol 2, No 2 (2019)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v2i2.20

Abstract

Tuberculosis is one of the most significant diseases which causes death worldwide. TB infection is assumed to infect the lungs only from a general perspective. In fact, TB infection also causes lesions on the skin. Scrofuloderma, as one of the most common types of cutaneous tuberculosis, often misdiagnosed and managed improperly due to its similarity with abscess. In addition, there were still no national and international guidelines for scrofuloderma. This review to give insights and review about an update in the basic principle of scrofuloderma and management.
PERAN TERAPI SPIRITUAL (LOGOTERAPI DAN ALCOHOLIC ANONYMUS ) PADA PASIEN GANGGUAN MENTAL DAN PERILAKU AKIBAT PENGGUNAAN ZAT MULTIPEL (ALKOHOL DAN NIKOTIN) ARYANI, LUH NYOMAN ALIT; KOSIM, HARTONO
HEALTHY : Jurnal Inovasi Riset Ilmu Kesehatan Vol. 3 No. 3 (2024)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/healthy.v3i2.3438

Abstract

Rehabilitation is a recovery process for patients with drug use disorders, either in the short or long term, which aims to change their behavior so that they are ready to return to society. Drug users also need to be saved so they can return to living a healthy and productive life. One approach given is spiritual therapy. The aim of this case report is to evaluate the effectiveness of spiritual interventions that can improve the quality of life and improve existing symptoms in addiction patients. Spiritual therapy was analyzed for its effect on general symptoms and improvement of perception and motivation in these patients. The patient is male, 59 years old, Dutch citizen, no religion, married status, last degree, experiences discomfort and restlessness, it is very difficult to be fully conscious, when he wants to walk the patient is very easy to fall, vomit and has levator pain ani. With spiritual approaches, namely logotherapy and alcoholic anonymus, which are added to standard treatment, patients become calm and no longer hopeless and the motivation appears to continue treatment and psychotherapy. Currently, the patient is much better and can begin to carry out activities and work as before. ABSTRAKRehabilitasi adalah suatu proses pemulihan pasien gangguan penggunaan NAPZA baik dalam jangka waktu pendek ataupun panjang yang bertujuan mengubah perilaku mereka agar siap kembali ke masyarakat. Pengguna narkoba juga perlu diselamatkan agar dapat kembali menjalani hidup dalam keadaan sehat dan produktif. Salah satu pendekatan yang diberikan adalah dengan terapi spiritual. Tujuan dari laporan kasus ini adalah untuk mengevaluasi efektivitas intervensi spiritual yang dapat meningkatkan kualitas hidup dan memperbaiki gejala yang ada pada pasien adiksi. Terapi spiritual dianalisis pengaruhnya terhadap gejala umum dan perbaikan persepsi dan motivasi pada pasien ini. Pasien laki-laki, 59 tahun warga negara Belanda, tidak beragama, status menikah, pendidikan terakhir sarjana, mengalami rasa tidak nyaman dan gelisah, sulit sekali untuk bisa sadar sepenuhnya. Ketika dia berjalan, pasien sangat mudah untuk terjatuh, ada muntah dan memiliki sakit levator ani. Dengan pendekatan spiritual yaitu logoterapi dan alcoholic anonymus yang ditambahkan pada pengobatan standar, pasien menjadi tenang dan tidak putus asa lagi serta motivasinya muncul untuk melanjutkan pengobatan dan psikoterapi. Saat ini pasien sudah jauh lebih baik serta mulai bisa beraktivitas dan bekerja seperti semula.
GANGGUAN CAMPURAN CEMAS DAN DEPRESI PADA PASIEN PEMFIGUS FOLIACEUS: LAPORAN KASUS DENGAN PENDEKATAN PSIKIATRI LIAISON Kosim, Hartono; Wardani, Ida Aju Kusuma; Ariani, Ni Ketut Putri; Mahardika, I Komang Ana
PAEDAGOGY : Jurnal Ilmu Pendidikan dan Psikologi Vol. 5 No. 1 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia (P4I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/paedagogy.v5i1.5120

Abstract

Pemphigus foliaceus is a chronic autoimmune disease that attacks the superficial layers of the epidermis, causing painful and aesthetically disturbing skin lesions. In addition to physical impacts, this disease can also trigger psychological disorders such as mixed anxiety and depressive disorders, which are often unrecognized by medical personnel. This report discusses the case of a 45-year-old female patient with active pemphigus foliaceus, who presented with complaints of excessive anxiety, depressed mood, insomnia, and decreased social function. The diagnosis was made as mixed anxiety and depressive disorder (F41.2, PPDGJ III). The Consultation-Liaison Psychiatry (CLP) approach was applied, including pharmacological interventions in the form of selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines, as well as non-pharmacological interventions such as supportive psychotherapy, relaxation techniques, and psychoeducation. The CLP approach emphasizes collaboration between dermatologists and psychiatrists for comprehensive treatment. This multidisciplinary management has been proven effective in improving the clinical prognosis and quality of life of patients with dermatological and psychiatric comorbidities. Early detection and integration of mental health services are essential for optimal therapy outcomes. ABSTRAKPemfigus foliaceus merupakan penyakit autoimun kronis yang menyerang lapisan superfisial epidermis, menyebabkan lesi kulit yang nyeri dan mengganggu penampilan. Selain dampak fisik, penyakit ini juga dapat memicu gangguan psikologis seperti gangguan campuran cemas dan depresi, yang sering tidak dikenali oleh tenaga medis. Laporan ini membahas kasus seorang pasien perempuan berusia 45 tahun dengan pemfigus foliaceus aktif, yang datang dengan keluhan cemas berlebihan, suasana hati depresif, insomnia, serta penurunan fungsi sosial. Diagnosis ditegakkan sebagai gangguan campuran cemas dan depresi (F41.2, PPDGJ III). Pendekatan Consultation-Liaison Psychiatry (CLP) diterapkan, mencakup intervensi farmakologis berupa selective serotonin reuptake inhibitor (SSRI) dan benzodiazepin, serta intervensi nonfarmakologis seperti psikoterapi suportif, teknik relaksasi, dan psikoedukasi. Pendekatan CLP menekankan kolaborasi antara spesialis dermatologi dan psikiatri untuk penanganan komprehensif. Penatalaksanaan multidisipliner ini terbukti efektif dalam meningkatkan prognosis klinis dan kualitas hidup pasien dengan komorbiditas dermatologis dan psikiatris. Deteksi dini dan integrasi layanan kesehatan jiwa sangat penting untuk hasil terapi yang optimal.
Co-Authors Agung Mahariski, Pande Ariani, Ni Ketut Putri Christopher, Paulus Mario Luh Nyoman Alit Aryani, Luh Nyoman Alit MAHARDIKA, I KOMANG ANA Marianto Marianto Silvi Suhardi, Silvi Wardani, Ida Aju Kusuma Wijaya, Ratna Sari Wijayadi, Linda Julianti