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Penanda Infeksi Pada Pemeriksaan Darah Rutin Syafina, Ikhfana
BEST Journal (Biology Education, Sains and Technology) Vol 7, No 2 (2024): September 2024
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v7i2.9802

Abstract

Penyakit infeksi adalah gangguan yang disebabkan oleh organisme, biasanya dalam ukuran mikroskopis, seperti bakteri, virus, jamur, atau parasit yang ditularkan, langsung atau tidak langsung, dari satu orang ke orang lain. Manusia juga dapat terinfeksi setelah terpapar dengan hewan yang terinfeksi yang memiliki organisme patogen yang mampu menginfeksi manusia. Tubuh manusia selalu terpapar terhadap bakteri, virus, parasit dan jamur. Dimana banyak dari agen infeksius ini dapat menimbulkan gangguan fungsi fisiologis dan penyakit. Pemeriksaan darah merupakan pemeriksaan laboratorium yang cepat, simpel dan efektif dalam menilai respon terhadap infeksi. Pemeriksaan darah terdiri dari leukosit, eritrosit, hemoglobin, hematokrit, indeks eritrosit dan trombosit dimana pemeriksaan leukosit ditambah leukosit diferensial. Parameter laboratorium reaktan fase akut yang lazim diperiksa, yaitu laju endap darah (LED), C-Reactive Protein (CRP), dan procalcitonin (PCT).
Penanda Infeksi Pada Pemeriksaan Darah Rutin Syafina, Ikhfana
BEST Journal (Biology Education, Sains and Technology) Vol 7, No 2 (2024): September 2024
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v7i2.9802

Abstract

Penyakit infeksi adalah gangguan yang disebabkan oleh organisme, biasanya dalam ukuran mikroskopis, seperti bakteri, virus, jamur, atau parasit yang ditularkan, langsung atau tidak langsung, dari satu orang ke orang lain. Manusia juga dapat terinfeksi setelah terpapar dengan hewan yang terinfeksi yang memiliki organisme patogen yang mampu menginfeksi manusia. Tubuh manusia selalu terpapar terhadap bakteri, virus, parasit dan jamur. Dimana banyak dari agen infeksius ini dapat menimbulkan gangguan fungsi fisiologis dan penyakit. Pemeriksaan darah merupakan pemeriksaan laboratorium yang cepat, simpel dan efektif dalam menilai respon terhadap infeksi. Pemeriksaan darah terdiri dari leukosit, eritrosit, hemoglobin, hematokrit, indeks eritrosit dan trombosit dimana pemeriksaan leukosit ditambah leukosit diferensial. Parameter laboratorium reaktan fase akut yang lazim diperiksa, yaitu laju endap darah (LED), C-Reactive Protein (CRP), dan procalcitonin (PCT).
Tingkat Kepatuhan Minum Obat Anti Tuberkulosis (OAT) Berhubungan Terhadap Kesembuhan Pasien Tuberkulosis Paru Di Rumah Sakit Umum Daerah Rokan Hulu Pratiwi, Dea Destyamanda; Syafina, Ikhfana
JURNAL PANDU HUSADA Vol 6, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v6i3.22027

Abstract

Abstrak : Tuberkulosis (TB) ialah suatu penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Pengobatan pada pasien penyakit tuberkulosis, yaitu dengan obat Anti-Tuberkulosis (OAT). Kepatuhan minum obat merupakan faktor penting yang berpengaruh langsung terhadap kesembuhan pasien TB paru. Pengobatan TB paru membutuhkan durasi setidaknya 6 bulan, hal ini dapat mengakibatkan ketidakpatuhan pasien dalam menjalani pengobatan. Penelitian ini bertujuan menganalisis hubungan tingkat kepatuhan minum OAT terhadap kesembuhan pasien TB paru di Rumah Sakit Umum Daerah Rokan Hulu dilakukan pada Oktober-Desember 2023. Penelitian ini merupakan penelitian observasional analitik dengan desain cross sectional. Jumlah sampel 31 orang. Teknik pengambilan sampel adalah purposive sampling. Pengolahan data menggunakan aplikasi statistika SPSS dengan menggunakan Chi-Square (p0,05). Hasil penelitian ini mayoritas pasien tingkat kepatuhan tinggi dinyatakan sembuh 26 orang (83,9%) pasien tingkat kepatuhan tinggi dinyatakan tidak sembuh 2 orang (6,5%), sedangkan tingkat kepatuhan sedang dinyatakan sembuh 1 orang (3,2%) pasien tingkat kepatuhan sedang dinyatakan tidak sembuh 2 orang (6,5%). Berdasarkan analisis data terdapat hasil yang signifikan (p=0,003) yang menunjukkan bahwa adanya hubungan tingkat kepatuhan minum OAT terhadap pasien TB paru di Rumah Sakit Umum Daerah Rokan Hulu. 
Vitamin C Consumption Affects the Treatment Period of Covid-19 Patients at Dr. Pirngadi Regional General Hospital Mahardika, Virani; Syafina, Ikhfana; Hapsah, Hapsah; Arbaningsih, Sri Rezeki
Buletin Farmatera Vol 10, No 1 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i1.23946

Abstract

Abstract: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) or what we now know as Coronavirus disease (COVID-19) is a viral infection that has hit the world in the last three years. The management of patients confirmed with COVID-19 continues to be researched. Vitamin C is one of the therapies that can be given to COVID-19 patients from mild to severe or critical degrees. Vitamin C is an antioxidant whose function can reduce oxidative inflammation and greatly affect the human immune system. The dose of vitamin C administration in COVID-19 patients can be given up to high doses. Due to the protective properties of vitamin C, it can affect the treatment period of COVID-19 patients. This study aims to determine the relationship between vitamin C consumption and the length of treatment of COVID-19 patients at DR Pirngadi General Hospital. This study is an observational analytical study with a cross-sectional design. A total of 66 samples were obtained divided into low and high doses of vitamin C which were then analyzed using Chi Square. The results of the study found that there was a significant result (P=0.039) in the relationship between vitamin C consumption and the treatment period of COVID-19 patients. Vitamin C consumption affects the treatment period. 
Edukasi Rasionalisasi Penggunaan Antibiotik pada Kasus Pneumonia di Masyarakat Syafina, Ikhfana
Mitra Abdimas: Jurnal Pengabdian kepada Masyarakat Vol 5 No 1 (2025)
Publisher : Medan Resource Center

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pneumonia remains a major public health concern, often treated improperly with antibiotics. This study aims to explore the impact of community-based education on the rational use of antibiotics for pneumonia. Using a qualitative descriptive approach, data were collected through participatory observation, in-depth interviews, and focus group discussions. The findings reveal that most participants initially misunderstood antibiotic functions and frequently used them without prescriptions. After interactive educational sessions, participants showed improved understanding and expressed a strong commitment to responsible antibiotic use. The involvement of local health workers and community leaders played a vital role in enhancing program effectiveness. This study highlights the importance of structured, community-oriented education in promoting rational antibiotic practices and preventing antimicrobial resistance. The success of this initiative suggests its potential to be scaled up and replicated in other communities facing similar health behavior challenges.
Knowing and Understanding the Tuberculosis (Tb) Disease of the Lung (Literature Review) Arsyad, M. Hatadi; Syafina, Ikhfana; Hapsah, Hapsah; Hervina, Hervina
International Journal of Natural Science Studies and Development (IJOSS) Vol. 1 No. 2 (2024): IJOSS
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijoss.v1i2.15

Abstract

Tuberculosis is a highly prevalent disease among individuals. The bacteria may enter the human body with inhaled air, after which they will be taken into the lungs, and then might disseminate from the lungs into the other parts of the body via the circulatory system, lymphatic system, respiratory tract-bronchi, or by direct passage to other areas. The most affected organs with tuberculosis are the lungs, but it may also affect other organs, including the meninges, bones, superficial glands, and other organs. They include: India, 26%; Indonesia, 8.5%; China, 8.4%; the Philippines, 6%; Pakistan, 5.7%; Nigeria, 4.4%; Bangladesh, 3.6%; and South Africa, 3.6%. These eight countries account for two-thirds of the global cases put together. 8.2% of tuberculosis cases are co-infected with HIV. Targeted by the national tuberculosis control program is the elimination of tuberculosis by 2035 and attainment of a tuberculosis-free status by 2050. Methods: This study is based on a review of general clinical practice guidelines, research publications, websites, and textbooks on pulmonary tuberculosis. Findings and Analysis: There are various research writings about the clinical presentations of the condition, confirmatory investigations for Mycobacterium tuberculosis, the epidemiology of the patients, and risk conditions that predispose a patient to getting infected by the bacteria. Therapeutic interventions and pharmacological adverse effects. Conclusion Pulmonary tuberculosis is a communicable disease, and Indonesia still has a population that carries this infection. Thus, prevention of the disease should be done by every single individual in society by understanding and knowing the character of the disease.